Visceral leishmaniasis in Birigui, SP, Brazil: evaluation of its occurrence in space and effectiveness of control measures

• Grant number: 16/25878-7
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: April 01, 2017
• End date: December 31, 2017
• Field of knowledge: Health Sciences - Collective Health - Epidemiology
• Principal Investigator: Eunice Aparecida Bianchi Galati
• Grantee: Patricia Marques Moralejo Bermudi
• Host Institution: Faculdade de Saúde Pública (FSP). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Visceral leishmaniasis (VL), a neglected disease, has three elements of important interaction in their epidemic process, for which the control measures are focused: the reservoir, through the identification and euthanasia of positive dogs; the vector, by chemical control; and the host, by the identification and treatment of human cases. There are doubts in Brazil, about the effectiveness of this control. The occurrence of the disease both in country and in the state of São Paulo (ESP), and in the city of Birigui-SP, has presented a dispersal process, with the increase of incidence. Birigui presented as higher rates in recent years in relation to its administrative region. Objectives: To describe and evaluate the epidemiological process of VL, its occurrence in space and time and the effectiveness of control measures in the city of Birigui-SP, during the period from 2006 to 2015. Methods: The study will occur in the urban area of Birigui. The coverage of canine and vector control activities will be estimated and evaluated, the human incidence rates standardized by age and sex will be estimated and the association of these with the coverage of the control activities will be evaluated. The results of these analyzes obtained for Birigui will be compared with those of Araçatuba, obtained in a previous study. Risk areas of occurrence of VL will be detected through the use of scanning statistics and the existence of spatial dependence between the distribution of canine and human cases will be verified, using the bivariate Ripley K function. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MORALEJO BERMUDI, PATRICIA MARQUES; CARNEIRO CASTRO COSTA, DANIELLE NUNES; NUNES, CANIS MARONI; TOLEZANO, JOSE EDUARDO; HIRAMOTO, ROBERTO MITSUYOSHI; COLEBRUSCO RODAS, LILIAN APARECIDA; CIPRIANO, RAFAEL SILVA; BLANGIARDO, MARTA; CHIARAVALLOTI-NETO, FRANCISCO. Canine serological survey and dog culling ant its relationship with human visceral leishmaniasis in an endemic urban area. BMC INFECTIOUS DISEASES, v. 20, n. 1, JUN 5 2020. (14/17764-6, 14/06518-4, 16/25878-7, 17/09671-6)