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Identification and characterization of spider Phoneutria nigriventer isolated venom, with chemotherapeutic effect on brain tumor cells

Grant number: 17/05402-0
Support type:Scholarships in Brazil - Technical Training Program - Technical Training
Effective date (Start): May 01, 2017
Effective date (End): April 30, 2019
Field of knowledge:Biological Sciences - Pharmacology - General Pharmacology
Principal researcher:Catarina Raposo Dias Carneiro
Grantee:Amanda Pires Bonfanti
Home Institution: Instituto de Biologia (IB). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Associated research grant:15/04194-0 - Identification of new molecules with chemotherapeutic effect in human glioma and characterization of the mechanism, AP.JP
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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
BARRETO, NATALIA; CABALLERO, MARCUS; BONFANTI, AMANDA PIRES; PINHEIRO DE MATO, FELIPE CEZAR; MUNHOZ, JAQUELINE; DA ROCHA-E-SILVA, THOMAZ A. A.; SUTTI, RAFAEL; VITORINO-ARAUJO, JOAO LUIZ; VERINAUD, LIANA; RAPOSO, CATARINA. Spider venom components decrease glioblastoma cell migration and invasion through RhoA-ROCK and Na+/K+-ATPase beta 2: potential molecular entities to treat invasive brain cancer. CANCER CELL INTERNATIONAL, v. 20, n. 1 DEC 17 2020. Web of Science Citations: 0.
BONFANTI, AMANDA PIRES; BARRETO, NATALIA; MUNHOZ, JAQUELINE; CABALLERO, MARCUS; CORDEIRO, GABRIEL; ROCHA-E-SILVA, THOMAZ; SUTTI, RAFAEL; MOURA, FERNANDA; BRUNETTO, SERGIO; RAMOS, CELSO DARIO; THOME, RODOLFO; VERINAUD, LIANA; RAPOSO, CATARINA. Spider venom administration impairs glioblastoma growth and modulates immune response in a non-clinical model. SCIENTIFIC REPORTS, v. 10, n. 1 APR 3 2020. Web of Science Citations: 1.
DOS SANTOS, NATALIA BARRETO; BONFANTI, AMANDA PIRES; ALVES DA ROCHA-E-SILVA, THOMAZ AUGUSTO; DA SILVA, JR., PEDRO ISMAEL; DA CRUZ-HOFLING, MARIA ALICE; VERINAUD, LIANA; RAPOSO, CATARINA. Venom of the Phoneutria nigriventer spider alters the cell cycle, viability, and migration of cancer cells. Journal of Cellular Physiology, v. 234, n. 2, p. 1398-1415, FEB 2019. Web of Science Citations: 1.

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