Production of bounded interdigitated electrodes for biosensors for detection of cancer biomarkers

• Grant number: 17/12096-3
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: August 01, 2017
• End date: February 28, 2018
• Field of knowledge: Physical Sciences and Mathematics - Physics - Condensed Matter Physics
• Principal Investigator: Osvaldo Novais de Oliveira Junior
• Grantee: Roberto Hiroshi Matos Furuta
• Host Institution: Instituto de Física de São Carlos (IFSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil
• Associated research grant: 13/14262-7 - Nanostructured films from biologically-relevant materials, AP.TEM

Abstract

Diagnostic techniques for early cancers of different types of cancer are of great relevance, given that cancer is the third most common cause of death in developing countries. One of the strategies to identify the disease is to detect biomarkers with biosensors, such as those based on measurements of electrical impedance and capacitance. This type of biosensor allows the detection of analytes without using markers and with little treatment of the sample under analysis. This project intends to produce inexpensive printed interdigitated electrodes for capacitive biosensors used in the detection of cancer biomarkers. The electrodes will be produced with screen printing on cheap and flexible substrates, such as plastic and paper. To construct the biosensors, the electrodes will be covered with different nanomaterials aiming at the optimization of the electrical and analytical properties. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

IBANEZ-REDIN, GISELA; FURUTA, ROBERTO H. M.; WILSON, DEIVY; SHIMIZU, FLAVIO M.; MATERON, ELSA M.; REBOLHO BATISTA ARANTES, LIDIA MARIA; MELENDEZ, MATIAS E.; CARVALHO, ANDRE L.; REIS, RUI MANUEL; CHAUR, MANUEL N.; et al. Screen-printed interdigitated electrodes modified with nanostructured carbon nano-onion films for detecting the cancer biomarker CA19-9. Materials Science & Engineering C-Materials for Biological Applications, v. 99, p. 1502-1508, JUN 2019. (17/12096-3, 13/14262-7, 15/01770-0, 16/00991-5, 12/15543-7)