Associations of maternal exposure to air pollution on birth outcomes: a prospective cohort study

• Grant number: 16/14433-4
• Support type: Scholarships in Brazil - Doctorate
• Effective date (Start): July 01, 2017
• Effective date (End): June 30, 2019
• Field of knowledge: Health Sciences - Medicine - Maternal and Child Health
• Cooperation agreement: Coordination of Improvement of Higher Education Personnel (CAPES)
• Principal researcher: Lisandra Stein Bernardes Ciampi de Andrade
• Grantee: Mariana Azevedo Carvalho
• Home Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Air pollution is the result of complex interactions that involve emissions of air pollutants and it causes adverse effects on human health. Some studies show that exposure to air pollution during pregnancy can cause low birth weight and prematurity, however it is not well understood which are the critical windows of exposure to air pollution during pregnancy. In order to investigate better the impact of air pollution on pregnancy and fetus, the aim of this project is to evaluate the influence of exposure to air pollution during pregnancy on birth outcomes, as the growth of the cephalic circumference. A prospective cohort study of 386 pregnant women, entitled ProcriAR, is being held in the city of São Paulo. Nitrogen dioxide (NO2) and ozone (O3) are measured during each trimester of pregnancy using passive personal samplers (APIs). At the same time, the analysis of carbon monoxide (CO), NO2 and particulate matter with an aerodynamic diameter less than 10 microns (PM10) are measured by the fixed monitoring station's Taboão da Serra of the Environmental Company of São Paulo State (CETESB), which is the nearest region where the pregnant women live. So, this project proposes to assess which are the critical windows of exposure to air pollution during pregnancy and which are the effects caused by air pollution on birth outcomes. Therefore, we could have consistent results in order to find more effective solutions to air pollution. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CARVALHO, MARIANA AZEVEDO; HETTFLEISCH, KAREN; RODRIGUES, AGATHA S.; BENACHI, ALEXANDRA; VIEIRA, SANDRA ELISABETE; SALDIVA, SILVIA R. D. M.; SALDIVA, PAULO HILARIO N.; FRANCISCO, ROSSANA PULCINELI VIEIRA; BERNARDES, LISANDRA STEIN. Association between exposure to air pollution during intrauterine life and cephalic circumference of the newborn. Environmental Science and Pollution Research, v. 28, n. 8, NOV 2020. (08/57717-6, 16/14433-4)

CARVALHO, MARIANA AZEVEDO; HETTFLEISCH, KAREN; RODRIGUES, AGATHA S.; BENACHI, ALEXANDRA; VIEIRA, SANDRA ELISABETE; SALDIVA, SILVIA R. D. M.; SALDIVA, PAULO HILARIO N.; VIEIRA FRANCISCO, ROSSANA PULCINELI; BERNARDES, LISANDRA STEIN. Association between maternal exposure to air pollution before conception and sex determination in the city of Sao Paulo. AIR QUALITY ATMOSPHERE AND HEALTH, v. 13, n. 10, JUL 2020. (08/57717-6, 16/14433-4)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

CARVALHO, Mariana Azevedo. Effects of maternal exposure to air pollution on birth outcomes. 2019. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Medicina (FM/SBD) São Paulo.