Fluid-structure simulation of (DAV) InCor pulsatile pediatric ventricular assist device

• Grant number: 17/20994-1
• Support Opportunities: Scholarships in Brazil - Post-Doctorate
• Effective date (Start): November 01, 2017
• Effective date (End): June 30, 2019
• Field of knowledge: Engineering - Biomedical Engineering - Medical Engineering
• Principal Investigator: Idágene Aparecida Cestari
• Grantee: Mohammad Malekan
• Host Institution: Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil
• Associated research grant: 12/50283-6 - Circulatory support in pediatric patients: ventricular assist device and extracorporeal membrane oxygenation, AP.TEM

Abstract

In this research, we will address a set of computational techniques for fluid-structure interaction (FSI) that allow realistic simulations of fluid dynamics within the DAV INCOR pulsatile pediatric ventricular assist device. The simulations involve dynamic interaction between two compartments filled with air and blood and a thin membrane separating the two compartments.Heart failure is an important cause of morbidity and mortality and a survival of approximately 2 to 3 years after diagnosis. Although a small number of patients may qualify for heart transplants, this is limited by strict selection criteria and lack of availability of donor hearts. In industrialized countries, patients with advanced heart failure without response to pharmacological treatment have options for using mechanical circulatory assistance devices until waiting for heart transplantation. In Brazil, due to the high cost of imported systems, the use of ventricular assist devices is practically inexistent, justifying the development of a national technology. This work aims to contribute to the development of the pediatric VAD INCOR. The computational approach adopted in this work will include the large buckling movements of the DAV membrane and the need to employ strongly coupled FSI solution strategies due to the mass effect present. The FSI methods will help to study the behavior of the fluid and the structure of the DAV, and also their interaction with each other.

Scientific publications

(6)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

KHOSRAVI, ALI; MALEKAN, MOHAMMAD. Effect of the magnetic field on the heat transfer coefficient of a Fe3O4-water ferrofluid using artificial intelligence and CFD simulation. EUROPEAN PHYSICAL JOURNAL PLUS, v. 134, n. 3, MAR 4 2019. (17/20994-1)

KHOSRAVI, ALI; MALEKAN, MOHAMMAD; ASSAD, MAMDOUH E. H.. Numerical analysis of magnetic field effects on the heat transfer enhancement in ferrofluids for a parabolic trough solar collector. RENEWABLE ENERGY, v. 134, p. 54-63, APR 2019. (17/20994-1)

MALEKAN, MOHAMMAD; KHOSRAVI, ALI; ZHAO, XIAOWEI. The influence of magnetic field on heat transfer of magnetic nanofluid in a double pipe heat exchanger proposed in a small-scale CAES system. APPLIED THERMAL ENGINEERING, v. 146, p. 146-159, JAN 5 2019. (17/20994-1)

MALEKAN, MOHAMMAD; CARVALHO, HERMES. Analysis of a main fatigue crack interaction with multiple micro-cracks/voids in a compact tension specimen repaired by stop-hole technique. JOURNAL OF STRAIN ANALYSIS FOR ENGINEERING DESIGN, v. 53, n. 8, SI, p. 648-662, NOV 2018. (17/20994-1)

SANTANA, GUILHERME ANDRE; MALEKAN, MOHAMMAD; ARAUJO, ALEXANDRE MARTINS; DONADON, LAZARO VALENTIM; CIMINI JR, CARLOS ALBERTO. Finite element evaluation of the effects of curvature in Lamb waves for composites structural health monitoring. LATIN AMERICAN JOURNAL OF SOLIDS AND STRUCTURES, v. 15, n. 10, 2018. (17/20994-1)

MALEKAN, MOHAMMAD; KHOSRAVI, ALI; CIMINI JR, CARLOS A.. Deformation and fracture of cylindrical tubes under detonation loading: A review of numerical and experimental analyses. INTERNATIONAL JOURNAL OF PRESSURE VESSELS AND PIPING, v. 173, p. 114-132, JUN 2019. (17/20994-1)