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Morbimortality related to Hospital de Câncer de Barretos sarcoma treatments

Grant number: 17/02437-8
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): February 01, 2018
Effective date (End): January 31, 2019
Field of knowledge:Health Sciences - Medicine - Surgery
Principal Investigator:Vinicius de Lima Vazquez
Grantee:Letícia Maria Modes da Costa
Home Institution: Hospital do Câncer de Barretos. Fundação Pio XII (FP). Barretos , SP, Brazil

Abstract

Sarcomas are a heterogeneous group of malignant neoplasms. They are divided in tumors of parts soft and bony. Histopathological diagnosis is often complex and regularized based on his own histological provenance or resemblance, and in case of undetermined, one denomination is made another, mainly the immunohistochemical examination. Its etiology can't be defined in most cases as a well-defined relationship between these tumors and radiation exposure, Stewart syndrome, Li Fraumeni syndrome, Gardner syndrome, neurofibromatosis type 1. Sarcomas are uncommon neoplasms, representing less than 1% of solid tumors in adults, being more frequent in children, corresponding to up to 15% of neoplasias in this group. The TNM classification influences strongly the survival of the carriers. The prognosis depends on the characteristics of the neoplasm, the patient's performance and the therapeutic options. Preferential treatment is surgical, may or not use adjuvant radiotherapy. Adjuvant chemotherapy is indicated in some specific cases. The research will do a characterization of sarcoma patients in the Hospital de Câncer de Barretos than had all their procedures within the institution. Focus will be given in the analysis of morbimortality data related to the patient and tumor, graded according to CTCAE (Common Criteria for Adverse Events Terminology) version 5.0. Such data should be used as an important tool for daily practice and future research. (AU)