Longitudinal association between biological maturation, body fatness and sports participation predicting the risk of metabolic syndrome and C-reactive protein: structural equation modelling (ABCD - growth study)

• Grant number: 17/27234-2
• Support Opportunities: Scholarships in Brazil - Master
• Effective date (Start): May 01, 2018
• Effective date (End): February 29, 2020
• Field of knowledge: Health Sciences - Physical Education
• Acordo de Cooperação: Coordination of Improvement of Higher Education Personnel (CAPES)
• Principal Investigator: Rômulo Araújo Fernandes
• Grantee: André de Oliveira Werneck
• Host Institution: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil
• Associated scholarship(s): 18/19183-1 - Lifestyle behaviors and health indicators throughout adolescence and emerging adulthood, BE.EP.MS

Abstract

Aim: To analyze after 12 months of follow - up the impact of advances in biological maturation on changes in components of the metabolic syndrome and inflammation among adolescents, as well as to identify the possible mediating role of adiposity and sports practice in such phenomenon. Methods: A longitudinal study started in 2017 (ABCD-GROWTH STUDY), in which data from 12-months follow-up will be collected in 2018. At least 236 adolescents aged 11 to 16 from the municipality of Presidente Prudente/Brazil will be evaluated. Participants will be contacted at 13 school units and sports clubs. Anthropometric measurements will be performed in order to estimate biological maturation (age at peak height velocity). Sports participation will be monitored throughout the 12 months of follow-up. Adiposity will be assessed by dual energy radiological densitometry. As outcome, the metabolic syndrome risk score (calculated by summing the z-scores of HDL-c, triglycerides, mean blood pressure and HOMA) and C-reactive protein will be adopted. For the statistics, will be conducted models of structural equation. Expected findings: It is expected to quantify the impact of maturational development on variables of cardiovascular risk of adolescents, as well as the roles assumed by the practice of physical activities and adipose tissue in such phenomenon. (AU)

Scientific publications

(29)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

AGOSTINETE, RICARDO R.; WERNECK, ANDRE O.; MAILLANE-VANEGAS, SANTIAGO; GRACIA-MARCO, LUIS; UBAGO-GUISADO, ESTHER; CONSTABLE, ANNIE M.; FERNANDES, ROMULO A.; VLACHOPOULOS, DIMITRIS. The Mediating Role of Lean Soft Tissue in the Relationship between Somatic Maturation and Bone Density in Adolescent Practitioners and Non-Practitioners of Sports. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, v. 18, n. 6, MAR 2021. (17/09182-5, 16/20354-0, 16/06920-2, 18/24164-6, 13/06963-5, 15/13543-8, 15/19710-3, 17/27234-2)

ANDRÉ O. WERNECK; RICARDO R. AGOSTINETE; MANOEL CARLOS S. DE LIMA; BRUNA C. TURI-LYNCH; ROMULO A. FERNANDES. The effects of physical activity during childhood, adolescence, and adulthood on cardiovascular risk factors among adults. Revista da Associação Médica Brasileira, v. 65, n. 11, p. 1337-1342, 2019-12-02. (17/09182-5, 17/27234-2)

WERNECK, ANDRE O.; CHRISTOFARO, DIEGO G. D.; RITTI-DIAS, RAPHAEL M.; CUCATO, GABRIEL G.; CONCEICAO, RAQUEL D. O.; SANTOS, RAUL D.; BITTENCOURT, MA'RCIO S.. Self-initiated changes in physical activity and incidence of Metabolic Syndrome: A longitudinal follow-up study. Diabetes Research and Clinical Practice, v. 165, JUL 2020. (17/27234-2)

SILVA, DANILO R.; MINDERICO, CLAUDIA S.; JUDICE, PEDRO B.; WERNECK, ANDRE O.; OHARA, DAVID; CYRINO, EDILSON S.; SARDINHA, LUIS B.. Agreement Between GT3X Accelerometer and ActivPAL Inclinometer for Estimating and Detecting Changes in Different Contexts of Sedentary Time Among Adolescents. JOURNAL OF PHYSICAL ACTIVITY & HEALTH, v. 16, n. 9, p. 780-784, SEP 2019. (17/27234-2)

ANDRÉ OLIVEIRA WERNECK; RÔMULO ARAÚJO FERNANDES; DANILO RODRIGUES SILVA. Economic crises, behavioral changes and hospitalization due to affective disorders in Brazil between 2003 and 2017: a nationwide cross-sectional study. São Paulo Medical Journal, v. 138, n. 2, p. 167-170, 2020-04-09. (17/27234-2)

WERNECK, ANDRE O.; VANCAMPFORT, DAVY; OYEYEMI, ADEWALE L.; SZWARCWALD, CELIA L.; STUBBS, BRENDON; SILVA, DANILO R.. Lifestyle behaviors among 4,343 Brazilian adults with severe mental illness and 55,859 general population controls: data from the Brazilian National Health Survey. Revista Brasileira de Psiquiatria, v. 42, n. 3, p. 245-249, MAY-JUN 2020. (17/27234-2)

WERNECK, ANDRE O.; OYEYEMI, ADEWALE L.; CYRINO, EDILSON S.; RONQUE, V, ENIO R.; SZWARCWALD, CELIA L.; COELHO-E-SILVA, MANUEL J.; SILVA, DANILO R.. Association between age at menarche and blood pressure in adulthood: is obesity an important mediator?. HYPERTENSION RESEARCH, v. 41, n. 10, p. 856-864, OCT 2018. (17/27234-2)

WERNECK, ANDRE OLIVEIRA; AGOSTINETE, RICARDO RIBEIRO; CAYRES, SUZIANE UNGARI; URBAN, JACQUELINE BEXIGA; WIGNA, ANDREA; DE MORAES CHAGAS, LUCAS GABRIEL; TORRES, WESLEY; FERNANDES, ROMULO ARAUJO. Association between Cluster of Lifestyle Behaviors and HOMA-IR among Adolescents: ABCD Growth Study. MEDICINA-LITHUANIA, v. 54, n. 6, DEC 2018. (15/04961-0, 17/09182-5, 15/19710-3, 17/27234-2)

WERNECK, ANDRE O.; OYEYEMI, ADEWALE L.; COLLINGS, PAUL J.; CYRINO, EDILSON S.; RONQUE, V, ENIO R.; SZWARCWALD, CELIA L.; SARDINHA, LUIS B.; SILVA, DANILO R. P.. Physical activity can attenuate, but not eliminate, the negative relationships of high TV viewing with some chronic diseases: findings from a cohort of 60 202 Brazilian adults. JOURNAL OF PUBLIC HEALTH, v. 43, n. 1, p. E7-E15, MAR 2021. (17/27234-2)

WERNECK, ANDRE O.; RONQUE, V, ENIO R.; FERNANDES, ROMULO A.. Structural equation model of the effect of biological maturation on metabolic syndrome risk and C-reactive protein: effect of trunk fat and sports participation. SCIENTIFIC REPORTS, v. 11, n. 1, SEP 10 2021. (15/19710-3, 18/22593-7, 17/27234-2)

LUIZ-DE-MARCO, RAFAEL; KEMPER, HAN; AGOSTINETE, RICARDO RIBEIRO; WERNECK, ANDRE OLIVEIRA; MAILLANE-VANEGAS, SANTIAGO; FAUSTINO-DA-SILVA, YURI DA SILVA; EXUPERIO, ISABELLA; FERNANDES, ROMULO ARAUJO. Sports participation and muscle mass affect sex-related differences in bone mineral density between male and female adolescents: A longitudinal study. São Paulo Medical Journal, v. 137, n. 1, p. 75-81, JAN-FEB 2019. (17/13003-9, 16/20354-0, 17/09182-5, 15/19710-3, 17/27234-2, 16/20377-0)

TAVARES, OSCAR M.; DUARTE, JOAO P.; WERNECK, ANDRE O.; COSTA, DANIELA C.; SOUSA-E-SILVA, PAULO; MARTINHO, DIOGO; LUZ, LEONARDO G. O.; MOROUCO, PEDRO; VALENTE-DOS-SANTOS, JOAO; SOLES-GONCALVES, RUI; et al. Composição corporal, força estática e isocinética, e saúde óssea: estudo comparativo entre adultos ativos e futebolistas amadores. Einstein (São Paulo), v. 17, n. 3, 2019. (17/27234-2)

CAYRES, SUZIANE UNGARI; WERNECK, ANDRE OLIVEIRA; URBAN, JACQUELINE BEXIGA; TURI-LYNCH, BRUNA CAMILO; BARBOSA, MAURICIO FREGONESI; FERNANDES, ROMULO ARAUJO. Sports participation is inversely associated with C-reactive protein levels in adolescents: ABCD Growth Study. SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS, v. 29, n. 7, p. 1000-1005, JUL 2019. (15/04961-0, 15/19710-3, 17/27234-2)

DANILO RODRIGUES PEREIRA DA SILVA; ANDRÉ OLIVEIRA WERNECK; PAUL COLLINGS; RÔMULO ARAÚJO FERNANDES; ENIO RICARDO VAZ RONQUE; LUÍS BETTENCOURT SARDINHA; EDILSON SERPELONI CYRINO. Identifying children who are susceptible to dropping out from physical activity and sport: a cross-sectional study. São Paulo Medical Journal, v. 137, n. 4, p. 329-335, 2019-10-31. (17/27234-2)

WERNECK, ANDRE O.; COLLINGS, PAUL J.; BARBOZA, LUCIANA L.; STUBBS, BRENDON; SILVA, DANILO R.. Associations of sedentary behaviors and physical activity with social isolation in 100,839 school students: The Brazilian Scholar Health Survey. GENERAL HOSPITAL PSYCHIATRY, v. 59, p. 7-13, JUL-AUG 2019. (17/27234-2)

ALESSANDRA MADIA MANTOVANI; ANDRÉ OLIVEIRA WERNECK; RICARDO RIBEIRO AGOSTINETE; MANOEL CARLOS SPIGUEL LIMA; JAMILE SANCHES CODOGNO; BRUNA CAMILO TURI-LYNCH; RÔMULO ARAÚJO FERNANDES. Impact of physical activity during weekdays and weekends on fat mass among adults: 12-month cohort study. São Paulo Medical Journal, v. 138, n. 3, p. 201-207, 2020-05-11. (15/20460-1, 17/50026-7, 17/27234-2, 17/09182-5)

WERNECK, ANDRE O.; OYEYEMI, ADEWALE L.; SZWARCWALD, CELIA L.; SARDINHA, LUIS B.; SILVA, DANILO R.. Body mass index trajectories and noncommunicable diseases in women: The role of leisure time physical activity. AMERICAN JOURNAL OF HUMAN BIOLOGY, v. 33, n. 3, SEP 2020. (17/27234-2)

BUENO, MARIA RAQUEL DE OLIVEIRA; ZAMBRIN, LIDYANE FERREIRA; PANCHONI, CAMILA; WERNECK, ANDRE OLIVEIRA; FERNANDES, ROMULO ARAUJO; SERASSUELO, HELIO; ROMANZINI, MARCELO; RONQUE, ENIO RICARDO VAZ. Association Between Device-Measured Moderate-to-Vigorous Physical Activity and Academic Performance in Adolescents. HEALTH EDUCATION & BEHAVIOR, v. 48, n. 1, p. 54-62, FEB 2021. (17/27234-2)

WERNECK, ANDRE O.; STUBBS, BRENDON; SZWARCWALD, CELIA L.; SILVA, DANILO R.. Independent relationships between different domains of physical activity and depressive symptoms among 60,202 Brazilian adults. GENERAL HOSPITAL PSYCHIATRY, v. 64, p. 26-32, MAY-JUN 2020. (17/27234-2)

AGOSTINETE, RICARDO RIBEIRO; VLACHOPOULOS, DIMITRIS; WERNECK, ANDRE OLIVEIRA; MAILLANE-VANEGAS, SANTIAGO; LYNCH, KYLE ROBINSON; NAUGHTON, GERALDINE; FERNANDES, ROMULO ARAUJO. Bone accrual over 18 months of participation in different loading sports during adolescence. ARCHIVES OF OSTEOPOROSIS, v. 15, n. 1, APR 25 2020. (17/27234-2, 15/13543-8, 17/09182-5, 13/06963-5, 18/24164-6, 16/20354-0, 16/06920-2, 16/20377-0)

WERNECK, ANDRE O.; VANCAMPFORT, DAVY; OYEYEMI, ADEWALE L.; STUBBS, BRENDON; SILVA, DANILO R.. Joint association of ultra-processed food and sedentary behavior with anxiety-induced sleep disturbance among Brazilian adolescents. Journal of Affective Disorders, v. 266, p. 135-142, APR 1 2020. (17/27234-2)

WERNECK, ANDRE O.; OYEYEMI, ADEWALE L.; SZWARCWALD, CELIA L.; SILVA, DANILO R.. Association between physical activity and alcohol consumption: sociodemographic and behavioral patterns in Brazilian adults. JOURNAL OF PUBLIC HEALTH, v. 41, n. 4, p. 781-787, DEC 2019. (17/27234-2)

WERNECK, ANDRE O.; SILVA, DANILO R.. Population density, depressive symptoms, and suicidal thoughts. Revista Brasileira de Psiquiatria, v. 42, n. 1, p. 105-106, JAN-FEB 2020. (18/19183-1, 17/27234-2)

WERNECK, ANDRE O.; SILVA, EVELYN C. A.; BUENO, MARIA R. O.; VIGNADELLI, LIDYANE Z.; OYEYEMI, ADEWALE L.; ROMANZINI, CATIANA L. P.; RONQUE, V, ENIO R.; ROMANZINI, MARCELO. Association(s) Between Objectively Measured Sedentary Behavior Patterns and Obesity Among Brazilian Adolescents. PEDIATRIC EXERCISE SCIENCE, v. 31, n. 1, p. 37-41, FEB 2019. (17/27234-2)

WERNECK, ANDRE O.; BALDEW, SE-SERGIO; JAIME MIRANDA, J.; DIAZ ARNESTO, OSCAR; STUBBS, BRENDON; SILVA, DANILO R.; ACTIVITY, SOUTH AMER PHYSICAL. Physical activity and sedentary behavior patterns and sociodemographic correlates in 116,982 adults from six South American countries: the South American physical activity and sedentary behavior network (SAPASEN). International Journal of Behavioral Nutrition and Physical Activity, v. 16, n. 1, AUG 20 2019. (17/27234-2)

AGOSTINETE, RICARDO RIBEIRO; FERNANDES, ROMULO ARAUJO; NARCISO, PEDRO HENRIQUE; MAILLANE-VANEGAS, SANTIAGO; WERNECK, ANDRE OLIVEIRA; VLACHOPOULOS, DIMITRIS. Categorizing 10 Sports According to Bone and Soft Tissue Profiles in Adolescents. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, v. 52, n. 12, p. 2673-2681, DEC 2020. (16/20354-0, 13/06963-5, 18/24164-6, 17/09182-5, 15/19710-3, 17/27234-2, 16/06920-2, 18/21935-1)

WERNECK, ANDRE O.; SILVA, DANILO R.; OYEYEMI, ADEWALE L.; FERNANDES, ROMULO A.; STEENE-JOHANNESEN, JOSTEIN; ANDERSEN, LARS BO; NORTHSTONE, KATE; SARDINHA, LUIS B.; ANDERSSEN, S.; CARDON, G.; et al. Physical activity attenuates metabolic risk of adolescents with overweight or obesity: the ICAD multi-country study. International Journal of Obesity, v. 44, n. 4, JAN 2020. (17/27234-2)

WERNECK, ANDRE OLIVEIRA; SILVA, DANILO RODRIGUES; COLLINGS, PAUL JAMES; FERNANDES, ROMULO ARAUJO; VAZ RONQUE, ENIO RICARDO; SARDINHA, LUIS BETTENCOURT; CYRINO, EDILSON SERPELONI. Fatores pré-natais, biológicos e ambientais associados à manutenção da atividade física da infância à adolescência. Ciênc. saúde coletiva, v. 24, n. 3, p. 1201-1210, MAR 2019. (17/27234-2)

ANDRADE-LIMA, ALUISIO; WERNECK, ANDRE O.; SZWARCWALD, CELIA L.; SCHUCH, FELIPE B.; STUBBS, BRENDON; BASTOS, AFRANIO A.; SILVA, DANILO R.. The role of physical activity in the association between multimorbidity and depressive symptoms: Data from 60,202 adults from the Brazilian National Health Survey. JOURNAL OF PSYCHOSOMATIC RESEARCH, v. 134, JUL 2020. (17/27234-2)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

WERNECK, André de Oliveira. Longitudinal association between biological maturation, body fat and sports practice in predicting metabolic syndrome risk and c-reactive protein: structural equation models (abcd: growth study). 2020. Master's Dissertation - Universidade Estadual Paulista (Unesp). Faculdade de Ciências e Tecnologia. Presidente Prudente Presidente Prudente.