Self-assembly of thermo- and magneto-responsive building blocks for the fabrication of novel biomarkers

• Grant number: 18/16330-3
• Support type: Scholarships abroad - Research Internship - Post-doctor
• Effective date (Start): November 30, 2018
• Effective date (End): September 29, 2019
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Physical-Chemistry
• Principal researcher: Watson Loh
• Grantee: Aline Grein Iankovski
• Supervisor abroad: Jean-Francois Berret
• Home Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Research place: Université Paris Diderot - Paris 7, France
• Associated to the scholarship: 17/04571-3 - Magnetic Janus nanoparticles, BP.PD

Abstract

The proposed project aims the development of nanomaterials with specific and multiple functionalities. The idea is to prepare superparamagnetic iron oxide nanoparticles and functionalize their surfaces with different phosphonic acid-terminated polymers, combining the thermoresponsive PNIPAM (poly (N-isopropylacrylamide)) and PEO (poly(ethyleneoxide)) to modulate the nanoparticles interfacial and self-assembly properties. The co-addition of these two polymers would also fine tune the temperature-induced phase transition reversibility. The potential applicability of the prepared hybrid materials as biomarkers for biological applications will be investigated. The combination of a thermoresponsive polymer and a magnetic nanoparticle into a single material with intermediate wettability and possibly a surface organization (patchy or Janus) might pave the way to novel smart nanomaterials applications.

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

RADIOM, MILAD; HENAULT, ROMAIN; MANI, SALMA; IANKOVSKI, ALINE GREIN; NOREL, XAVIER; BERRET, JEAN-FRANCOIS. Magnetic wire active microrheology of human respiratory mucus. SOFT MATTER, v. 17, n. 32 JUL 2021. Web of Science Citations: 0.

GREIN-IANKOVSKI, ALINE; GRAILLOT, ALAIN; LOH, WATSON; BERRET, JEAN-FRANCOIS. Stimuli-responsive assembly of iron oxide nanoparticles into magnetic flexible filaments. EMERGENT MATERIALS, MAR 2021. Web of Science Citations: 0.

GREIN-IANKOVSKI, ALINE; GRAILLOT, ALAIN; RADIOM, MILAD; LOH, WATSON; BERRET, JEAN-FRANCOIS. Template-Free Preparation of Thermoresponsive Magnetic Cilia Compatible with Biological Conditions. Journal of Physical Chemistry C, v. 124, n. 47, p. 26068-26075, NOV 25 2020. Web of Science Citations: 0.

GREIN-IANKOVSKI, ALINE; LOH, WATSON. Modulating the interfacial properties of magnetic nanoparticles through surface modification with a binary polymer mixture towards stabilization of double emulsions. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, v. 586, FEB 5 2020. Web of Science Citations: 2.