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Population genomics of Pilocarpus spp. (Rutaceae)

Grant number: 18/17236-0
Support type:Scholarships in Brazil - Post-Doctorate
Effective date (Start): October 01, 2018
Effective date (End): April 30, 2019
Field of knowledge:Biological Sciences - Botany
Principal Investigator:Pedro Dias de Oliveira
Grantee:Otávio Luis Marques da Silva
Home Institution: Escola Superior de Agricultura Luiz de Queiroz (ESALQ). Universidade de São Paulo (USP). Piracicaba , SP, Brazil
Associated research grant:14/18002-2 - Sapindales: phylogeny and diversification in the Neotropical Region, AP.TEM


The genus Pilocarpus Vahl has 17 species and its distribution is restricted to the Neotropics. Economically, it is noteworthy by being the only natural source of the alkaloid pilocarpine, which is the key element commercialised by the pharmaceutical industry for glaucoma treatment. This project will focus on the four closely related, commercially exploited, and pilocarpine-producing species: P. alatus, P. jaborandi, P. microphyllus and P. trachylophus. This project will use Oxford Nanopore and Illumina sequencing technologies.

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