| Grant number: | 18/17831-6 |
| Support Opportunities: | Scholarships abroad - Research Internship - Post-doctor |
| Start date: | December 01, 2018 |
| End date: | November 30, 2019 |
| Field of knowledge: | Physical Sciences and Mathematics - Chemistry - Physical-Chemistry |
| Principal Investigator: | Lauro Tatsuo Kubota |
| Grantee: | Sergio Kogikoski Junior |
| Supervisor: | Ilko Bald |
| Host Institution: | Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil |
| Institution abroad: | University of Potsdam, Germany |
| Associated to the scholarship: | 16/14507-8 - Structural and Electrochemical Studies of Nanostructures films based on DNA, BP.PD |
Abstract Energy transfer processes are of fundamental interest for the development of devices for electronics, plasmonics, catalysis and correlated applications. Usually those processes occur in very organized systems, with well positioned functional materials, one classic example is the photosysthesis assembly, which converts light energy into chemical products through a process in which energy is transferred by a cascade of coupled metalloproteins. However, it is not easy to obtain such high level of organization and structuration, in that way the use of techniques that allow the precise orthogonal assembly of different components in 2D or 3D shapes is necessary. In the last decade, the technique of DNA origami is being used to overcome many limitations of microfabrication procedures reaching high precision and yields in the nanoscale. Herein we propose the use of DNA origami technique to precisely assemble metal nanoparticles for surface enhance Raman spectroscopy studies. The DNA assemblies will be self-assembled using the protocols developed by Dr. Ilko Bald's group in Potsdam. The DNA origami technique is not available yet in Brazil, but holds great promises for the advancement of many interdisciplinary applications, such as nanocircuits, nanomachines, nanoreactors, nanosensors, etc. Our projects in Brazil so far used nanoparticles modified with DNA, which due to the base pair complementarity self-assembled into crystalline superlattices. These films, however lack local fine control of the nanoparticle arrangement. DNA origami, on the other hand offers precise control over the orthogonal placement of different kinds of nanoparticles, ligands, biomolecules and DNA strands in almost any arbitrary 2D and 3D arrangements as well as over interparticle spacing and the exact local arrangement. The knowledge of this technique is of high interest since it could generate specific assemblies that are properly designed for novel bioanalytical interfaces, moreover the understanding of energy transfer processes can enhance its applicability, sensibility and detection limits obtaining a new generation of bioanalytical devices. | |
| News published in Agência FAPESP Newsletter about the scholarship: | |
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