Advanced search
Start date

Study about sex chromosomes from Megaleporinus elongatus based in satellite DNA sequences

Grant number: 18/12906-8
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): October 01, 2018
Effective date (End): November 30, 2021
Field of knowledge:Biological Sciences - Genetics - Animal Genetics
Principal researcher:Patricia Pasquali Parise Maltempi
Grantee:Evelin Mariani Gonçalves
Home Institution: Instituto de Biociências (IB). Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Rio Claro , SP, Brazil


Sex chromosomes evolved independently during evolution of the vertebrate group, in a way that their pattern of evolution succeeds differently from the autosomal chromosomes. Regarding fish there is great diversity of sex chromosome systems, presenting both homomorphic and heteromorphic sex chromosomes throughout the group. In heteromorphic sex chromosomes, in one of the homologs, Y or the W, it may occur a vast presence of heterochromatin, rich in repetitive sequences. One example of these sequences, the satellite DNA class, may be related to the evolutionary process of sex chromosomes differentiation due to their highly dynamic characteristics. The genus Megaleporinus is an interesting model for the study of sex chromosomes evolution in fish, due to some of its species presenting female heterogamety (ZZ/ZW), with an elevated rate of repetitive sequences in their heteromorphic sex chromosomes. The function and organization of these repetitive sequences in the sex chromosomes of fish is not yet known, therefore, this project has the objective to study the genomic organization and possible evolutionary history of M. elongatus sex chromosomes through satellite DNA sequences isolation, amplification and probe hybridization in of both sexes of the species.

News published in Agência FAPESP Newsletter about the scholarship:
Articles published in other media outlets (0 total):
More itemsLess items