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Spatial-temporal dynamics of yellow fever virus in the State of São Paulo, Brazil

Grant number: 18/23364-1
Support type:Scholarships abroad - Research Internship - Post-doctor
Effective date (Start): April 01, 2019
Effective date (End): August 31, 2019
Field of knowledge:Biological Sciences - Ecology
Principal Investigator:Jean Paul Walter Metzger
Grantee:Paula Ribeiro Prist
Supervisor abroad: Jonathan Rhodes
Home Institution: Instituto de Biociências (IB). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Local de pesquisa : University of Queensland, Brisbane (UQ), Australia  
Associated to the scholarship:17/11666-0 - Yellow fever: transmission risk due to landscape changes and climate alterations, BP.PD

Abstract

Yellow fever is a hemorrhagic fever that affects about 200,000 people annually in the endemic regions. It is transmitted in its wild cycle through the bite of infected Haemagogus spp. and Sabethes spp. mosquitos, which are arboreal and abundant in fragmented and degrades landscapes. Connectivity among habitats is important for a wide range of ecological processes, including disease transmission, once it describes the degree to which an environment´s spatial configuration facilitates or impedes vectors flows. However, our understanding of how landscape connectivity modulates yellow fever virus dispersion remains limited. To understand these effects, nonhuman primates constitute a privileged study element, once they are the main hosts of the virus and serve as an alert to the health agencies about the circulation of the agent. Here we will use circuit theory to model yellow fever virus flow in 30 municipalities of the state of São Paulo, Brazil. In the first step we will create a cost surface that represent permeability of the landscape to movement for yellow fever virus. For this we will use as basis the land use land cover map created by The Brazilian Sustainable Development Foundation, for the year of 2013, and which have six classes: water, urban, agricultural, forest, natural non-forest and forestry areas. Then we will use epizootic coordinates events through São Paulo state as nodes and circuit theory to connect pairs of nodes. The date of each event will be used in order to understand the temporality of the virus dispersal. With the resistance values generate by the Circuit Scape program, we will calculate the least expensive route between nodes, creating a map of connectivity. Evaluating contributions of these factors to yellow fever risk may enable predictions of future outbreaks and is critical to development of effective public health strategies.

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
METZGER, JEAN PAUL; BUSTAMANTE, MERCEDES M. C.; FERREIRA, JOICE; FERNANDES, GERALDO WILSON; LIBRAN-EMBID, FELIPE; PILLAR, VALERIO D.; PRIST, PAULA R.; RODRIGUES, RICARDO RIBEIRO; VIEIRA, IMA CELIA G.; OVERBECK, GERHARD E.; SIGNATORIES, 407 SCIENTIST. Why Brazil needs its Legal Reserves. PERSPECTIVES IN ECOLOGY AND CONSERVATION, v. 17, n. 3, p. 91-103, JUL-SEP 2019. Web of Science Citations: 2.

Please report errors in scientific publications list by writing to: cdi@fapesp.br.