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Synthesis and characterization of polymeric modified scaffold with a bioactive molecule

Grant number: 19/05566-9
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): May 01, 2019
Effective date (End): April 30, 2020
Field of knowledge:Engineering - Biomedical Engineering
Principal Investigator:Carla dos Santos Riccardi
Grantee:Ananda Beatriz Passeto de Oliveira
Home Institution: Faculdade de Ciências Agronômicas (FCA). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil

Abstract

Tissue engineering provides a prospective new strategic by clinical applications to promote the regeneration of damaged or diseased tissues using biomaterials. In this work, a biocompatible polymer scaffold will be developed by solvent evaporation process. The scaffolds will be obtained under planar membrane mold and tubular prototypes. The project aims to obtain a device with antimicrobial, hemostatic properties and optimize aspects of flexibility. Therefore, morphological, physic-chemical, mechanical and biological properties will be characterized. The device is expected to exhibit distinct mechanical properties for suture fixation and application as vascular grafts.