Housing hygiene conditions affect postprandial profiles of amino acids and metabolites in pigs selected for low and high residual feed intake

• Grant number: 18/11807-6
• Support type: Scholarships in Brazil - Doctorate
• Effective date (Start): August 01, 2019
• Effective date (End): February 28, 2023
• Field of knowledge: Agronomical Sciences - Animal Husbandry - Animal Nutrition and Feeding
• Principal researcher: Luciano Hauschild
• Grantee: Alícia Zem Fraga
• Home Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil
• Associated research grant: 18/15559-7 - Precision nutrition for sanitary challenged pigs reared in hot climate areas, AP.JP2
• Associated scholarship(s): 19/23265-6 - Housing hygiene conditions affect postprandial profiles of amino acids and metabolites in pigs selected for low and high residual feed intake, BE.EP.DR

Abstract

The objective is to evaluate the effects of systemic inflammation induced by poor housing conditions on postprandial profiles of amino acids and metabolites in pigs divergently selected for Residual Feed Intake (RFI; a feed efficiency measure). Thirty-two growing pigs will be used in factorial planning 2x2 (n=8 pigs/group): two genetic lines (low-RFI and high-RFI) and two housing hygiene conditions (Good vs. Dirty). After a period of adaptation to the experimental conditions of three weeks, blood samples will be collected at 0, 15, 30, 45, 60, 75, 90, 105, 120, 150, 180, 210 e 240 min by an intravenous catheter fixed to each animal. Samples will be analyzed using commercial kits for estimate of plasma amino acid concentrations (essential and non-essential) and metabolites (glucose, urea, free fatty acids and insulin). After statistical analysis, the variations of the concentration of the different amino acids over time will be analyzed by the nonlinear regression model (Erlang Equation). The execution of this project will allow a better understanding of the effects of housing sanitary conditions on the metabolism of pigs. In addition, the expected results may be used in future projects in an attempt to mitigate the negative impacts of poor hygiene conditions on pig production. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ZEM FRAGA, ALICIA; LOUVEAU, ISABELLE; CAMPOS, PAULO HENRIQUE REIS FURTADO; HAUSCHILD, LUCIANO; LE FLOC'H, NATHALIE. Selection for feed efficiency elicits different postprandial plasma metabolite profiles in response to poor hygiene of housing conditions in growing pigs. PLoS One, v. 16, n. 3 MAR 29 2021. Web of Science Citations: 1.