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Role of TLR2 and TLR9-dependent signalling in epithelial or dendritic cells in lung inflammation during allergen reexposure and pneumococcal infection

Grant number: 19/09881-6
Support type:Scholarships in Brazil - Post-Doctorate
Effective date (Start): July 01, 2019
Effective date (End): June 30, 2022
Field of knowledge:Biological Sciences - Immunology - Cellular Immunology
Principal researcher:Vânia Luiza Deperon Bonato
Grantee:Thais Fernanda de Campos Fraga da Silva
Home Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
Associated research grant:17/21629-5 - Strategies to study pulmonary inflammation during comorbidities, AP.TEM

Abstract

Concerning asthma, the post-doctoral project entitled "Role of TLR2 and TLR9-dependent signalling in epithelial or dendritic cells in lung inflammation during allergen reexposureand pneumococcal infection" aims to determine the contribution of TLR2 and/or TLR9-dependent signalling in epithelial and/or myeloid cells for Th17 profile induction and neutrophil migration in asthma and pneumonia comorbidity.

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