Role of TLR2 and TLR9-dependent signalling in epithelial or dendritic cells in lung inflammation during allergen reexposure and pneumococcal infection

• Grant number: 19/09881-6
• Support type: Scholarships in Brazil - Post-Doctorate
• Effective date (Start): July 01, 2019
• Effective date (End): June 30, 2022
• Field of knowledge: Biological Sciences - Immunology - Cellular Immunology
• Principal researcher: Vânia Luiza Deperon Bonato
• Grantee: Thais Fernanda de Campos Fraga da Silva
• Home Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated research grant: 17/21629-5 - Strategies to study pulmonary inflammation during comorbidities, AP.TEM

Abstract

Concerning asthma, the post-doctoral project entitled "Role of TLR2 and TLR9-dependent signalling in epithelial or dendritic cells in lung inflammation during allergen reexposureand pneumococcal infection" aims to determine the contribution of TLR2 and/or TLR9-dependent signalling in epithelial and/or myeloid cells for Th17 profile induction and neutrophil migration in asthma and pneumonia comorbidity.