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Genetic algorithms and convolutional neural networks for computer-aided diagnosis of spinal compression fractures

Grant number: 19/01219-2
Support Opportunities:Scholarships in Brazil - Master
Effective date (Start): October 01, 2019
Effective date (End): March 31, 2020
Field of knowledge:Physical Sciences and Mathematics - Computer Science - Computing Methodologies and Techniques
Principal Investigator:Renato Tinós
Grantee:Rafael Silva Del Lama
Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
Associated research grant:13/07375-0 - CeMEAI - Center for Mathematical Sciences Applied to Industry, AP.CEPID


Spinal Compression Fracture (SCF) occurs when the vertebral body is collapsed. SCFs can be caused by trauma (benign SCFs) or tumors (malignant SCFs), and the investigation of the etiology of an SCF is essential for the determination of the patient's treatment. In this work, images of vertebrae obtained by Magnetic Resonance will be classified using Machine Learning. Currently, there has been a great interest in using Convolutional Neural Networks for the classification of medical images. However, such networks often require large databases that are often not available in medical applications. In addition, such networks generally do not use additional clinical information that may be important for classification. Here, different characteristics will be used for classification. The classification will be made by an Artificial Neural Network, which will have as inputs features extracted from three different sources: i) intermediate layers of Convolutional Neural Networks; ii) image preprocessing; (iii) additional clinical information. Due to the large number of available features, a Genetic Algorithm will be used for feature selection. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DEL LAMA, RAFAEL SILVA; CANDIDO, RAQUEL MARIANA; CHIARI-CORREIA, NATALIA SANTANA; NOGUEIRA-BARBOSA, MARCELLO HENRIQUE; DE AZEVEDO-MARQUES, PAULO MAZZONCINI; TINOS, RENATO. Computer-Aided Diagnosis of Vertebral Compression Fractures Using Convolutional Neural Networks and Radiomics. JOURNAL OF DIGITAL IMAGING, v. 35, n. 3, p. 13-pg., . (19/07665-4, 19/01219-2, 21/09720-2)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
LAMA, Rafael Silva Del. Genetic algorithms and convolutional neural networks to aid the diagnosis of compression vertebral fractures. 2020. Master's Dissertation - Universidade de São Paulo (USP). Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (PCARP/BC) Ribeirão Preto.

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