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Studies of mechanisms of activation and action of MMP2 and ADAM17: identification of regulatory proteins, oxidant production pathways, epigenetics and proteolytic targets

Grant number: 19/16089-7
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): September 01, 2019
Effective date (End): August 31, 2020
Field of knowledge:Biological Sciences - Biochemistry - Enzymology
Principal researcher:Raquel Fernanda Gerlach
Grantee:Lucas Pastore de Santana
Home Institution: Faculdade de Odontologia de Ribeirão Preto (FORP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Abstract

This project aims at learning how to produce and how to purify recombinant proteins, an important part of the work of Subprojects 3 and 4 of the Tematic Project. The student will carry out the kinetic analyses of each batch of recombinant protein.

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