Multifactorial analysis of anxiety disorders and depression in patients with epilepsy and caregivers

• Grant number: 19/11457-8
• Support Opportunities: Scholarships in Brazil - Master
• Effective date (Start): September 01, 2019
• Effective date (End): April 30, 2021
• Field of knowledge: Health Sciences - Medicine
• Principal Investigator: Clarissa Lin Yasuda
• Grantee: Rafael Batista João
• Host Institution: Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 13/07559-3 - BRAINN - The Brazilian Institute of Neuroscience and Neurotechnology, AP.CEPID

Abstract

Epilepsy is one of the most common neurological conditions, affecting 2-3% of the world's population. Such disorder may be related to the impairment of quality of life, mainly in cases associated with psychiatric comorbidities. Approximately 6% of patients with epilepsy (PWE) present concurrent psychiatric disorder, mainly depression and anxiety. Several studies were designed to determine the prevalence of anxiety and depression in this subpopulation; however, a few investigated factors related to the higher frequency and severity of such comorbidities. Thus, we aim to investigate the prevalence and severity of such disorders in PWE, comparing different syndromes and also the occurrence of these symptoms in caregivers. We will perform a multivariate analysis of clinical and epidemiological predictors through the application of validated screening tools. In addition, we intend to investigate the impact of anxiety/depression on brain connectivity by analyzing the resting state in patients with focal epilepsy. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

JOAO, RAFAEL BATISTA; NOGUEIRA, MATEUS HENRIQUE; MORITA-SHERMAN, MARCIA ELISABETE; ALVIM, MARINA KOUTSODONTIS MACHADO; JOHNNY, STEVEN; PEREIRA, HARYTON; PINHEIRO, HILDETE PRISCO; CENDES, FERNANDO; YASUDA, CLARISSA LIN. The Relationship Between Depression and Anxiety Symptoms of Adult PWE and Caregivers in a Tertiary Center. FRONTIERS IN NEUROLOGY, v. 13, p. 9-pg., 2022-03-09. (19/11457-8, 13/07559-3)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

JOÃO, Rafael Batista. Multifactorial evaluation of depressive symptoms, suicidal ideation and anxiety symptoms in people with Epilepsy and caregivers. 2021. Master's Dissertation - Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Médicas Campinas, SP.