Multifactorial analysis of anxiety disorders and depression in patients with epilepsy and caregivers

• Grant number: 19/11457-8
• Support Opportunities: Scholarships in Brazil - Master
• Start date: September 01, 2019
• End date: April 30, 2021
• Field of knowledge: Health Sciences - Medicine
• Principal Investigator: Clarissa Lin Yasuda
• Grantee: Rafael Batista João
• Host Institution: Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 13/07559-3 - BRAINN - The Brazilian Institute of Neuroscience and Neurotechnology., AP.CEPID

Abstract

Epilepsy is one of the most common neurological conditions, affecting 2-3% of the world's population. Such disorder may be related to the impairment of quality of life, mainly in cases associated with psychiatric comorbidities. Approximately 6% of patients with epilepsy (PWE) present concurrent psychiatric disorder, mainly depression and anxiety. Several studies were designed to determine the prevalence of anxiety and depression in this subpopulation; however, a few investigated factors related to the higher frequency and severity of such comorbidities. Thus, we aim to investigate the prevalence and severity of such disorders in PWE, comparing different syndromes and also the occurrence of these symptoms in caregivers. We will perform a multivariate analysis of clinical and epidemiological predictors through the application of validated screening tools. In addition, we intend to investigate the impact of anxiety/depression on brain connectivity by analyzing the resting state in patients with focal epilepsy. (AU)

Scientific publications

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

SCARDUA-SILVA, LUCAS; DA COSTA, BEATRIZ AMORIM; AVENTURATO, ITALO KARMANN; JOAO, RAFAEL BATISTA; DE CAMPOS, BRUNNO MACHADO; DE BRITO, MARIANA RABELO; BECHELLI, JOSE FLAVIO; SILVA, LEILA CAMILA SANTOS; DOS SANTOS, ALAN FERREIRA; ALVIM, MARINA KOUTSODONTIS MACHADO; et al. Microstructural brain abnormalities, fatigue, and cognitive dysfunction after mild COVID-19. SCIENTIFIC REPORTS, v. 14, n. 1, p. 12-pg., 2024-01-19. (19/23316-0, 21/09230-5, 22/11786-4, 20/04032-8, 19/11457-8)

JOAO, RAFAEL BATISTA; NOGUEIRA, MATEUS HENRIQUE; MORITA-SHERMAN, MARCIA ELISABETE; ALVIM, MARINA KOUTSODONTIS MACHADO; JOHNNY, STEVEN; PEREIRA, HARYTON; PINHEIRO, HILDETE PRISCO; CENDES, FERNANDO; YASUDA, CLARISSA LIN. The Relationship Between Depression and Anxiety Symptoms of Adult PWE and Caregivers in a Tertiary Center. FRONTIERS IN NEUROLOGY, v. 13, p. 9-pg., 2022-03-09. (19/11457-8, 13/07559-3)

CARREGARI, VICTOR C.; REIS-DE-OLIVEIRA, GUILHERME; CRUNFLI, FERNANDA; SMITH, BRADLEY J.; DE SOUZA, GABRIELA FABIANO; MURARO, STEFANIE PRIMON; SAIA-CEREDA, VERONICA M.; VENDRAMINI, PEDRO H.; BALDASSO, PAULO A.; SILVA-COSTA, LICIA C.; et al. Diving into the proteomic atlas of SARS-CoV-2 infected cells. SCIENTIFIC REPORTS, v. 14, n. 1, p. 14-pg., 2024-03-28. (13/07607-8, 13/07559-3, 20/05601-6, 14/10068-4, 17/25588-1, 13/08216-2, 19/11457-8, 19/00098-7, 20/04919-2, 20/04860-8, 20/04746-0)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

JOÃO, Rafael Batista. Multifactorial evaluation of depressive symptoms, suicidal ideation and anxiety symptoms in people with Epilepsy and caregivers. 2021. Master's Dissertation - Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Médicas Campinas, SP.