Development of paper-based electrochemical systems aiming flow analysis of forensic samples

• Grant number: 19/15065-7
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• Start date: October 01, 2019
• End date: May 09, 2024
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Thiago Regis Longo Cesar da Paixão
• Grantee: Iana Vitória Spadini Arantes
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated research grant: 18/08782-1 - Miniaturized and integrated chemical sensors: new fabrication platforms for biological, clinical and environmental applications, AP.TEM
• Associated scholarship(s): 22/07552-8 - Development of complete and miniaturized 3D-printed flow electrochemical systems for analytical applications, BE.EP.DD

Abstract

Paper is a low-cost, affordable and disposable platform that has been used as a substrate for chemical sensors in recent years and its use represents an alternative for carrying out chemical analysis in regions with limited resources. The manufacture of flow injection analysis systems using paper as a substrate instead of conventional FIA apparatus is still under-explored, requiring refinement for field application. Therefore, this project aims the study of microfluidic paper devices and its fabrication methods, as well as the integration of the electrochemical sensors directly on the substrate surface, through printing, laser scribing techniques and other techniques. The developed sensors will be characterized by different surface and characterization techniques. In addition, based on the paper properties, it will also be studied the possibility to propose the sensor manufacture as a paper swab to collect samples directly on contaminated surfaces aiming at forensic applications. (AU)

Scientific publications

(16)

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

ARANTES, IANA V. S.; CRAPNELL, ROBERT D.; BERNALTE, ELENA; WHITTINGHAM, MATTHEW J.; PAIXAO, THIAGO R. L. C.; BANKS, CRAIG E.. Mixed Graphite/Carbon Black Recycled PLA Conductive Additive Manufacturing Filament for the Electrochemical Detection of Oxalate. Analytical Chemistry, v. 95, n. 40, p. 8-pg., 2023-09-28. (22/07552-8, 19/15065-7)

CRAPNELL, ROBERT D.; ARANTES, IANA V. S.; WHITTINGHAM, MATTHEW J.; SIGLEY, EVELYN; KALINKE, CRISTIANE; JANEGITZ, BRUNO C.; BONACIN, JULIANO A.; PAIXAO, THIAGO R. L. C.; BANKS, CRAIG E.. Utilising bio-based plasticiser castor oil and recycled PLA for the production of conductive additive manufacturing feedstock and detection of bisphenol A. GREEN CHEMISTRY, v. 25, n. 14, p. 10-pg., 2023-06-22. (19/00473-2, 22/07552-8, 17/21097-3, 18/08782-1, 21/07989-4, 19/15065-7, 13/22127-2)

GONGONI, JULIANA L. M.; FILHO, LAURO A. P.; DE FARIAS, DAVI M.; ARANTES, IANA V. S.; PAIXAO, THIAGO R. L. C.. Modulating the Electrochemical Response of Eco-Friendly Laser-Pyrolyzed Paper Sensors Applied to Nitrite Determination. CHEMELECTROCHEM, v. 10, n. 1, p. 8-pg., 2022-12-21. (19/15065-7, 21/00205-8, 19/00811-5)

CRAPNELL, ROBERT D.; ARANTES, IANA V. S.; CAMARGO, JESSICA R.; BERNALTE, ELENA; WHITTINGHAM, MATTHEW J.; JANEGITZ, BRUNO C.; PAIXAO, THIAGO R. L. C.; BANKS, CRAIG E.. Multi-walled carbon nanotubes/carbon black/rPLA for high-performance conductive additive manufacturing filament and the simultaneous detection of acetaminophen and phenylephrine. Microchimica Acta, v. 191, n. 2, p. 12-pg., 2024-02-01. (23/00321-3, 17/21097-3, 19/15065-7, 19/23177-0, 22/07552-8, 18/08782-1)

FERREIRA, BRUNO; ARANTES, IANA V. S.; SARAIVA, DOUGLAS P. M.; PRADELA-FILHO, LAURO A.; BERTOTTI, MAURO; PAIXAO, THIAGO R. L. C.. Commercial ink-coated PVC: No longer abrading conventional PVC surfaces for electrode fabrication using pencil drawing. Microchemical Journal, v. 198, p. 7-pg., 2024-02-15. (23/02572-3, 21/00205-8, 19/15065-7, 18/08782-1, 22/11346-4)

FERREIRA, BRUNO; ARANTES, IANA V. S.; GONGONI, JULIANA L. M.; PRADELA-FILHO, LAURO A.; PAIXAO, THIAGO R. L. C.. Stencil-printed graphene electrodes for affordable electrochemical sensing of capsaicin. Microchemical Journal, v. 207, p. 7-pg., 2024-12-01. (19/15065-7, 18/08782-1, 23/00246-1, 21/00205-8)

ATAIDE, VANESSA N.; ARANTES, IANA V. S.; MENDES, LETICIA F.; ROCHA, DANIELLY S.; BALDO, THAISA A.; COLTRO, WENDELL K. T.; PAIXAO, THIAGO R. L. C.. Review-A Pencil Drawing Overview: From Graphite to Electrochemical Sensors/Biosensors Applications. Journal of the Electrochemical Society, v. 169, n. 4, p. 15-pg., 2022-04-01. (18/14462-0, 18/08782-1, 18/16250-0, 19/15065-7)

PRADELA-FILHO, LAURO A.; VELOSO, WILLIAM B.; ARANTES, IANA V. S.; GONGONI, JULIANA L. M.; DE FARIAS, DAVI M.; ARAUJO, DIELE A. G.; PAIXAO, THIAGO R. L. C.. Paper-based analytical devices for point-of-need applications. Microchimica Acta, v. 190, n. 5, p. 23-pg., 2023-05-01. (21/00205-8, 19/15065-7, 22/11346-4)

PRADELA-FILHO, LAURO A.; GONGONI, JULIANA L. M.; ARANTES, IANA V. S.; DE FARIAS, DAVI M.; PAIXAO, THIAGO R. L. C.. Controlling the Inkjet Printing Process for Electrochemical (Bio)Sensors. ADVANCED MATERIALS TECHNOLOGIES, v. N/A, p. 9-pg., 2023-01-29. (19/15065-7, 21/00205-8, 19/00811-5, 18/08782-1)

ARANTES, IANA V. S.; PAIXAO, THIAGO R. L. C.. ouple batch-injection analysis and microfluidic paper-based analytical device: A simple and disposable alternative to conventional BIA apparatu. Talanta, v. 240, APR 1 2022. (17/10522-5, 19/15065-7, 18/08782-1)

SILVA-NETO, HABDIAS A.; ARANTES, IANA V. S.; FERREIRA, ANDRE L.; DO NASCIMENTO, GUIDA H. M.; MELONI, GABRIEL N.; DE ARAUJO, WILLIAM R.; PAIXA, THIAGO R. L. C.; COLTRO, WENDELL K. T.. Recent advances on paper-based microfluidic devices for bioanalysis. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 158, p. 25-pg., 2022-12-27. (19/15065-7, 22/03382-0, 18/08782-1)

ARANTES, IANA V. S.; CRAPNELL, ROBERT D.; WHITTINGHAM, MATTHEW J.; SIGLEY, EVELYN; PAIXAO, THIAGO R. L. C.; BANKS, CRAIG E.. Additive Manufacturing of a Portable Electrochemical Sensor with a Recycled Conductive Filament for the Detection of Atropine in Spiked Drink Samples. ACS APPLIED ENGINEERING MATERIALS, v. 1, n. 9, p. 10-pg., 2023-09-07. (22/07552-8, 18/08782-1, 19/15065-7)

ARANTES, IANA V. S.; ATAIDE, VANESSA N.; AMEKU, WILSON A.; GONGONI, JULIANA L. M.; SELVA, JESSICA S. G.; NOGUEIRA, HELTON P.; BERTOTTI, MAURO; PAIXAO, THIAGO R. L. C.. Laser-induced fabrication of gold nanoparticles onto paper substrates and their application on paper-based electroanalytical devices. SENSORS & DIAGNOSTICS, v. 2, n. 1, p. 12-pg., 2023-01-19. (17/10522-5, 19/16491-0, 19/15065-7, 18/08782-1, 18/14462-0)

DE FARIAS, DAVI M.; PRADELA-FILHO, LAURO A.; ARANTES, IANA V. S.; GONGONI, JULIANA L. M.; VELOSO, WILLIAM B.; MELONI, GABRIEL N.; PAIXAO, THIAGO R. L. C.. Sulfanilamide Electrochemical Sensor Using Phenolic Substrates and CO₂ Laser Pyrolysis. ACS APPLIED MATERIALS & INTERFACES, v. 15, n. 48, p. 9-pg., 2023-11-20. (19/15065-7, 18/08782-1, 21/00205-8)

VELOSO, WILLIAM B.; MELONI, GABRIEL N.; ARANTES, IANA V. S.; PRADELA-FILHO, LAURO A.; MUNOZ, RODRIGO A. A.; PAIXAO, THIAGO R. L. C.. Gold film deposition by infrared laser photothermal treatment on 3D-printed electrodes: electrochemical performance enhancement and application. ANALYST, v. 149, n. 15, p. 11-pg., 2024-06-17. (21/00205-8, 22/03382-0, 21/00800-3, 19/15065-7, 23/00246-1, 22/11346-4)

FERREIRA, BRUNO; ARANTES, IANA V. S.; CRAPNELL, ROBERT D.; BERNALTE, ELENA; BANKS, CRAIG E.; PAIXAO, THIAGO R. L. C.. 3D printing pen for patterning electrochemical sensors on a paper platform for capsaicin detection. ANALYST, v. N/A, p. 8-pg., 2025-01-16. (19/15065-7, 23/00246-1)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

ARANTES, Iana Vitória Spadini. Development of integrated electroanalytical systems using alternative platforms aiming at flow analytical applications. 2024. Doctoral Thesis - Universidade de São Paulo (USP). Conjunto das Químicas (IQ e FCF) (CQ/DBDCQ) São Paulo.