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Encapsulation of Bacillus thuringiensis (Bacillales: Bacillaceae) in polymeric microparticles and association with nanoencapsulated chemical agent: evaluation of biological activity and mechanisms of action

Grant number: 18/21142-1
Support type:Scholarships in Brazil - Post-Doctorate
Effective date (Start): November 01, 2019
Effective date (End): October 31, 2021
Field of knowledge:Agronomical Sciences - Agronomy
Principal Investigator:Ricardo Antonio Polanczyk
Grantee:Jhones Luiz de Oliveira
Home Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil
Associated research grant:17/21004-5 - Agriculture, micro/nanotechnology and environment: from evaluation of the mechanisms of action to studies of transport and toxicity, AP.TEM


New technologies must be adopted with the objective of optimizing productivity and adding development to Brazilian agribusiness. However, this development must be based on environmentally sustainable strategies. Microencapsulation has been shown to be an excellent alternative to protect biological control agents from external factors, increasing their effectiveness. In the case of chemical control agents, the use of nanostructured systems has important characteristics such as the modified release, reduction of the amount of active and reduction of the toxicity to non-target organisms. In this context, this proposal intends to produce a hybrid system composed of the mixture of different Bacillus thuringiensis strains encapsulated in polymeric microparticles in association with a nanoparticle release system for chemical control agents. As steps, compatibility tests will be carried out between chemical and biological control agents. Subsequently, the nanocarriers for the chemical ingredients will be prepared and characterized. The hybrid systems will be produced and characterized, being evaluated the biological activity as well as studies of mechanism of action. In this way, the development of products that associate micro and nanotechnology with the encapsulation of control agents can be achieved through the integration between basic and applied science, providing alternatives to integrated pest management in Agriculture. (AU)

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DE ALBUQUERQUE, FELICIA PEREIRA; DE OLIVEIRA, JHONES LUIZ; MOSCHINI-CARLOS, VIVIANE; FRACETO, LEONARDO FERNANDES. An overview of the potential impacts of atrazine in aquatic environments: Perspectives for tailored solutions based on nanotechnology. Science of The Total Environment, v. 700, JAN 15 2020. Web of Science Citations: 0.

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