Encapsulation of Bacillus thuringiensis (Bacillales: Bacillaceae) in polymeric microparticles and association with nanoencapsulated chemical agent: evaluation of biological activity and mechanisms of action

• Grant number: 18/21142-1
• Support type: Scholarships in Brazil - Post-Doctorate
• Effective date (Start): November 01, 2019
• Effective date (End): November 01, 2022
• Field of knowledge: Agronomical Sciences - Agronomy - Plant Health
• Principal researcher: Ricardo Antonio Polanczyk
• Grantee: Jhones Luiz de Oliveira
• Home Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil
• Associated research grant: 17/21004-5 - Agriculture, micro/nanotechnology and environment: from evaluation of the mechanisms of action to studies of transport and toxicity, AP.TEM
• Associated scholarship(s): 20/12779-6 - Evaluation of the mechanisms of action of Bacillus thuringiensis (Bacillales: Bacillaceae) encapsulated in polymeric microparticles, BE.EP.PD

Abstract

New technologies must be adopted with the objective of optimizing productivity and adding development to Brazilian agribusiness. However, this development must be based on environmentally sustainable strategies. Microencapsulation has been shown to be an excellent alternative to protect biological control agents from external factors, increasing their effectiveness. In the case of chemical control agents, the use of nanostructured systems has important characteristics such as the modified release, reduction of the amount of active and reduction of the toxicity to non-target organisms. In this context, this proposal intends to produce a hybrid system composed of the mixture of different Bacillus thuringiensis strains encapsulated in polymeric microparticles in association with a nanoparticle release system for chemical control agents. As steps, compatibility tests will be carried out between chemical and biological control agents. Subsequently, the nanocarriers for the chemical ingredients will be prepared and characterized. The hybrid systems will be produced and characterized, being evaluated the biological activity as well as studies of mechanism of action. In this way, the development of products that associate micro and nanotechnology with the encapsulation of control agents can be achieved through the integration between basic and applied science, providing alternatives to integrated pest management in Agriculture. (AU)

Scientific publications

(7)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MONTEIRO, RENATA APARECIDA; CAMARA, MARCELA CANDIDO; DE OLIVEIRA, JHONES LUIZ; RAMOS CAMPOS, ESTEFANIA VANGELIE; CARVALHO, LUCAS BRAGANCA; DE FREITAS PROENCA, PATRICIA LUIZA; GUILGER-CASAGRANDE, MARIANA; LIMA, RENATA; DO NASCIMENTO, JOACIR; GONCALVES, KELLY CRISTINA; POLANCZYK, RICARDO ANTONIO; FRACETO, LEONARDO FERNANDES. Zein based-nanoparticles loaded botanical pesticides in pest control: An enzyme stimuli-responsive approach aiming sustainable agriculture. JOURNAL OF HAZARDOUS MATERIALS, v. 417, SEP 5 2021. Web of Science Citations: 2.

LUIS, ANGELICA I. S.; CAMPOS, ESTEFANIA V. R.; OLIVEIRA, JHONES L.; VALLIM, JOSE HENRIQUE; PROENCA, PATRICIA L. F.; CASTANHA, RODRIGO F.; DE CASTRO, VERA L. S. S.; FRACETO, LEONARDO F. Ecotoxicity evaluation of polymeric nanoparticles loaded with ascorbic acid for fish nutrition in aquaculture. JOURNAL OF NANOBIOTECHNOLOGY, v. 19, n. 1 MAY 31 2021. Web of Science Citations: 0.

DE ALBUQUERQUE, FELICIA PEREIRA; DE OLIVEIRA, JHONES LUIZ; DOS SANTOS MACHADO, LEILA; RICHARDI, VINICIUS SOBRINHO; DA SILVA, MARIO ANTONIO NAVARRO; POMPEO, MARCELO LUIZ MARTINS; FRACETO, LEONARDO FERNANDES; CARLOS, VIVIANE MOSCHINI. Use of nontarget organism Chironomus sancticaroli to study the toxic effects of nanoatrazine. ECOTOXICOLOGY, v. 30, n. 4, p. 733-750, MAY 2021. Web of Science Citations: 0.

DE OLIVEIRA, JHONES L.; FRACETO, LEONARDO FERNANDES; BRAVO, ALEJANDRA; POLANCZYK, RICARDO ANTONIO. Encapsulation Strategies for Bacillus thuringiensis: From Now to the Future. Journal of Agricultural and Food Chemistry, v. 69, n. 16, p. 4564-4577, APR 28 2021. Web of Science Citations: 0.

CAMARA, MARCELA CANDIDO; MONTEIRO, RENATA APARECIDA; CARVALHO, LUCAS BRAGANCA; OLIVEIRA, JHONES LUIZ; FRACETO, LEONARDO F. Enzyme Stimuli-Responsive Nanoparticles for Bioinsecticides: An Emerging Approach for Uses in Crop Protection. ACS SUSTAINABLE CHEMISTRY & ENGINEERING, v. 9, n. 1, p. 106-112, JAN 11 2021. Web of Science Citations: 1.

CAMPOS, ESTEFANIA V. R.; PEREIRA, ANDERSON E. S.; DE OLIVEIRA, JHONES LUIZ; CARVALHO, LUCAS BRAGANCA; GUILGER-CASAGRANDE, MARIANA; DE LIMA, RENATA; FRACETO, LEONARDO FERNANDES. How can nanotechnology help to combat COVID-19? Opportunities and urgent need. JOURNAL OF NANOBIOTECHNOLOGY, v. 18, n. 1 SEP 5 2020. Web of Science Citations: 39.

DE ALBUQUERQUE, FELICIA PEREIRA; DE OLIVEIRA, JHONES LUIZ; MOSCHINI-CARLOS, VIVIANE; FRACETO, LEONARDO FERNANDES. An overview of the potential impacts of atrazine in aquatic environments: Perspectives for tailored solutions based on nanotechnology. Science of The Total Environment, v. 700, JAN 15 2020. Web of Science Citations: 0.