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Healthy lifestyle promotion in patients with Systemic Lupus Erythematosus: effects on life quality and psychological aspects

Grant number: 19/14820-6
Support type:Scholarships in Brazil - Doctorate (Direct)
Effective date (Start): March 01, 2020
Effective date (End): February 29, 2024
Field of knowledge:Health Sciences - Medicine - Medical Clinics
Principal Investigator:Bruno Gualano
Grantee:Bruna Caruso Mazzolani
Home Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Systemic Lupus Erythematosus patients have a lower health-related quality of life when compared to the general population and also to other rheumatic and severe chronic diseases. Disease activity, pain, fatigue, treatment, comorbidities, demographic, social and emotional factors are predictors of a lower life quality in these patients. In theory, interventions to promote physical activity and health food consumption could improve life quality of Systemic Lupus Erythematous patients. This large randomized controlled trial ("Living Well with Lupus") aims to evaluate the effects of a new "real world" clinic intervention, that promotes structured and unstructured physical activity and health food consumption (based on Dietary Guideline for the Brazilian population), on cardiovascular risk, life quality, sleep quality and psychological aspects in Systemic Lupus Erythematous patients. In this thesis, specifically, the outcomes of interest are the ones associated with life quality, sleep quality and psychological aspects. Quantitative and qualitative methods will be used. Before and after intervention, will be evaluated: 1) physical activity level and sedentary behavior; 2) food consumption; 3) clinical parameters; 4) life quality; 5) psychological aspects (anxiety, depression); 6) sleep quality. Focus groups will be performed at the end of the follow-up to qualitatively evaluate intervention impacts. The findings of this project can fit as base for new prescriptions based in evidence with the aim to modify Systemic Lupus Erythematous patients life style. (AU)

News published in Agência FAPESP Newsletter about the scholarship:
Social distancing has changed Brazilian women’s eating habits, study shows 
Articles published in other media outlets (17 total):
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UOL: Isolamento social modifica a alimentação das brasileiras, aponta pesquisa (20/Nov/2020)
Folha.com: Isolamento social modificou comportamento alimentar das mulheres brasileiras, revela estudo (19/Nov/2020)
A Tribuna (Santos, SP) online: Comportamento alimentar das mulheres mudou na quarentena (24/Nov/2020)
Portal São José dos Campos: Isolamento social modifica o comportamento alimentar das mulheres brasileiras, revela estudo da USP (24/Nov/2020)
O Sul: O isolamento social muda o comportamento alimentar de brasileiras (23/Nov/2020)
O Sul online: O isolamento social muda o comportamento alimentar de brasileiras (22/Nov/2020)
Nuttrisaude: Isolamento social muda comportamento alimentar de brasileiras (22/Nov/2020)
ABCD Real: Isolamento social muda comportamento alimentar das mulheres brasileiras, mostra estudo (22/Nov/2020)
Plantão News (MT): Isolamento social modifica o comportamento alimentar das mulheres brasileiras, revela estudo (21/Nov/2020)
Dom Total: Comportamento alimentar de mulheres brasileiras mudou com o isolamento social (21/Nov/2020)
MSN: Isolamento social muda comportamento alimentar de brasileiras (20/Nov/2020)
MSN: Isolamento social modifica o comportamento alimentar das mulheres brasileiras, revela estudo (20/Nov/2020)
Planeta online: Isolamento social muda comportamento alimentar de brasileiras (20/Nov/2020)
Revista Pará: Isolamento social modifica o comportamento alimentar das mulheres brasileiras (20/Nov/2020)
Portal da Enfermagem: Isolamento social modifica o comportamento alimentar das mulheres brasileiras (20/Nov/2020)