Two-dimensional materials and their derivatives in photonic biosensoring of pathogens

• Grant number: 20/13288-6
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: April 01, 2021
• End date: October 31, 2024
• Field of knowledge: Physical Sciences and Mathematics - Physics - Condensed Matter Physics
• Principal Investigator: Christiano José Santiago de Matos
• Grantee: Jéssica Eliza Silva Fonsaca
• Host Institution: Instituto Mackenzie de Pesquisas em Grafeno e Nanotecnologias (Mackgraphe). Universidade Presbiteriana Mackenzie (UPM). São Paulo , SP, Brazil
• Associated scholarship(s): 23/04830-0 - Biofunctionalization of photonic waveguide biosensors for sepsis diagnosis, BE.EP.PD

Abstract

The class of two-dimensional (2D) materials and their nanostructured derivatives (e.g. heterostructures and nanocomposites) are considered promising for photonic devices for sensing devices, mainly because they present, in general, fast charge transfer kinetics, high surface area, easy functionalization and wide range of optical properties. In the face of the COVID-19 pandemic we are experiencing, these materials become deeply attractive for the development of nanobiosensors, potentially capable of detecting the most diverse pathogens - such as SARS-CoV-2 - in a simple, fast and sensitive way. With this application in mind, the present project aims at the synthesis of different materials based on graphene derivatives, graphitic carbon nitride, transition metal dichalcogenides and monochalcogenides of IV-VI groups, in their lamellar and 2D form, and heterostructures and nanocomposites based on these materials. The samples will be produced with controlled architecture (i.e. morphology, number of layers, layer size) and evaluated for their optical properties. The sensitivity of the materials that prove to be promising will be investigated based on a complex model (Biotin-Streptavidin), aiming at the optimization of the system for biosensing by optical phenomena: surface enhanced Raman spectroscopy and luminescence. Finally, we expect to contribute to the rational development of materials suitable for ultra-sensitive sensing, capable of reaching future practical applications. (AU)

Scientific publications

(10)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FONSACA, JESSICA E. S.; HOSTERT, LEANDRO; ZARBIN, ALDO J. G.; ORTH, ELISA S.. Chemical safety using functionalized carbon nanomaterials: neutralization and detection of organophosphorus compounds. JOURNAL OF MATERIALS CHEMISTRY A, v. 12, n. 14, p. 25-pg., 2024-02-26. (20/13288-6)

NAGAOKA, DANILO A.; GRASSESCHI, DANIEL; CADORE, ALISSON R.; FONSACA, JESSICA E. S.; JAWAID, ALI M.; VAIA, RICHARD A.; DE MATOS, CHRISTIANO J. S.. Redox exfoliated NbS2: characterization, stability, and oxidation. Physical Chemistry Chemical Physics, v. 25, n. 13, p. 10-pg., 2023-03-09. (20/04374-6, 18/25339-4, 20/13288-6)

DE AQUINO, CAROLINE BRAMBILLA; FONSACA, JESSICA ELIZA SILVA; DOMINGUES, SERGIO HUMBERTO. RuO2-WO3/PAni: combining the best of two classes of materials for a new energy storage device. Journal of Materials Science, v. 58, n. 15, p. 16-pg., 2023-04-07. (17/21988-5, 20/13288-6)

FONSACA, JESSICAE. S.; SILVA, EDERSON E.; TIEPPO, KAMILA; DOMINGUES, SERGIO H.; DE MATOS, CHRISTIANO J. S.. Nanostructured Co₃O₄ Semiconductors for Plasmon-Free SERS Sensing Platforms. ACS APPLIED NANO MATERIALS, v. 8, n. 15, p. 11-pg., 2025-04-08. (18/25339-4, 20/13288-6)

NETO, ANTONIO GOMES DOS SANTOS; SANTOS, ANA CAROLINE FERREIRA; JUNIOR, JOSE ANTONIO DE OLIVEIRA; JOST, CRISTIANE LUISA; SOUSA, CAMILA SILVA DE; GOULART, MARILIA OLIVEIRA FONSECA; SANTANA, ANTONIO EUZEBIO GOULART; GONZALEZ, SERGIO YESID GOMEZ; SILVA, EDERSON ESTEVES DA; FONSACA, JESSICA ELIZA SILVA; et al. Exploiting synergistic effects: Cheap ultra-sensitive electrochemical rutin detection using WO3/rGO nanocomposite in combination with multiwalled carbon nanotubes. Microchemical Journal, v. 193, p. 10-pg., 2023-10-01. (20/13288-6)

DE OLIVEIRA JR, JOSE ANTONIO; DOS SANTOS NETO, ANTONIO GOMES; DE SOUSA, CAMILA SILVA; RODRIGUES, THENNER SILVA; GARCIA, MARCO AURELIO SULLER; JOST, CRISTIANE LUISA; GONZALEZ, SERGIO YESID GOMEZ. Enhanced Isoproturon detection using AgPt nanotubes-based electrochemical sensor for water quality monitoring. Microchemical Journal, v. 205, p. 12-pg., 2024-08-06. (20/13288-6)

DOS SANTOS, CARLOS EDUARDO LIMA; FONSACA, JESSICA ELIZA SILVA; VELLO, TATIANA PARRA; OLIVEIRA, MARCELA MOHALLEM; DOMINGUES, SERGIO HUMBERTO. Tackling two different energy issues with one unique WS₂-WO₃/rGO nanocomposite: Energy storage and electrochemical hydrogen generation. Synthetic Metals, v. 311, p. 10-pg., 2025-04-01. (20/13288-6, 17/21988-5)

FONSACA, JESSICA E. S.; LIMA, CARLOS EDUARDO; MARTINS, KEVIN STEFAN BOSZKO; DOMINGUES, SERGIO H.; DE MATOS, CHRISTIANO J. S.. Covalently Linked 2D-Co₃O₄/GO Heterostructures: Catalytic and Electrochemical Properties. Langmuir, v. 40, n. 41, p. 11-pg., 2024-10-03. (23/04830-0, 18/25339-4, 20/13288-6)

FONSACA, JESSICA E. S.; TEIXEIRA, WANDERSON S. R.; TIEPPO, BIANCA; RAITZ, CESAR; REHAN, MOHD; GEROSA, RODRIGO M.; MEGID, JANE; APPOLINARIO, CAMILA M.; SALLES, MAIARA O.; SAITO, LUCIA A. M.; et al. Machine-learning-assisted waveguide scattering microscopy for the immunological detection of bovine brucellosis: A proof concept. SENSORS AND ACTUATORS B-CHEMICAL, v. 432, p. 10-pg., 2025-06-01. (23/04830-0, 22/07892-3, 18/25339-4, 20/13288-6)

FERREIRA, RAYSE MACHADO; DE LIMA, SCARLLETT LALESCA SANTOS; PEREIRA, FELLIPE DOS SANTOS; MOUCHREK, CHARBEL NAGIB; TAKANA, AURO ATSUSHI; DOMINGUES, SERGIO HUMBERTO; FONSACA, JESSICA ELIZA SILVA; LIU, LIYING; YATSUZUKA, REBECA; DA SILVA, ANDERSON GABRIEL MARQUES; et al. Nanowires-based MnO2-Ru/rGO: An efficient oxygen reduction reaction electrocatalyst. Applied Surface Science, v. 651, p. 11-pg., 2024-01-03. (20/13288-6)