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Influence of zinc on innate and acquired immune response in Haemonchus contortus infected lambs

Grant number: 21/03479-1
Support Opportunities:Scholarships in Brazil - Post-Doctoral
Start date: July 01, 2021
End date: February 28, 2023
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine
Principal Investigator:Alessandro Francisco Talamini Do Amarante
Grantee:Ana Claudia Alexandre de Albuquerque
Host Institution: Instituto de Biociências (IBB). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil
Associated research grant:19/26042-8 - Nanoparticle of zinc oxide as a functional feed, AP.TEM

Abstract

The studies will aim to establish the relationship between different dietary zinc levels and the efficiency of immune response against Haemonchus contortus infection in lambs. The postdoctoral will be involved in all activities of the experiment related to artificial infection of animals, determination of parasitic worm burden and immunological analyzes. Every two weeks, blood samples will be taken to determine antibody levels against Haemonchus contortus antigens. At the end of the study, the animals will be euthanized to determine the worm burden and to collect abomasum tissue and mucus samples, which will be subjected to immunological analysis. (AU)

News published in Agência FAPESP Newsletter about the scholarship:
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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
BELLO, HORNBLENDA JOAQUINA SILVA; LINS, JOSE GABRIEL GONCALVES; DE ALBUQUERQUE, ANA CLAUDIA ALEXANDRE; FERREIRA, GABRIEL BADIAL; AMARANTE, MONICA REGINA VENDRAME; DO AMARANTE, ALESSANDRO FRANCISCO TALAMINI. rophylactic Effects of Ivermectin and Closantel Treatment in the Control of Oestrus ovis Infestation in Shee. FRONTIERS IN VETERINARY SCIENCE, v. 8, . (21/03479-1, 19/25185-0)
LINS, JOSE GABRIEL G.; ALMEIDA, FABIANA A.; ALBUQUERQUE, ANA CLAUDIA A.; BRITTON, COLLETTE; AMARANTE, ALESSANDRO F. T.. Early-onset immune response to Haemonchus contortus infection in resistant Santa Ines suckling lambs compared with susceptible Ile de France. Veterinary Parasitology, v. 307-308, p. 10-pg., . (21/03479-1, 15/25718-7)