Effect of transcranial magnetic stimulation on non-painful symptoms in Fibromyalgia

• Grant number: 21/03996-6
• Support Opportunities: Scholarships in Brazil - Doctorate
• Effective date (Start): August 01, 2021
• Effective date (End): January 31, 2022
• Field of knowledge: Health Sciences - Medicine
• Principal Investigator: Daniel Ciampi Araujo de Andrade
• Grantee: Valquíria Aparecida da Silva
• Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

This is an adaptive clinical trial with fibromyalgia patients. It aims to assess the effect of long-term repetitive transcranial magnetic stimulation (EMR) on the non-painful symptoms of Fibromyalgia. Patients will be randomly allocated to two parallel arms (high dose of EMTr, sham) using adaptive methodology. The study will be conducted in a sequential methodology, the approximate sample size is 80 patients based on Bayesian analysis. (AU)