Effect of incorporation of zinc oxide nanoparticles and sodium trimetaphosphate microparticles on the physical-mechanical properties of a resin modified glass ionomer cement: in vitro study

• Grant number: 21/10742-0
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: March 01, 2022
• End date: February 28, 2023
• Field of knowledge: Health Sciences - Dentistry - Pediatric Dentistry
• Principal Investigator: Marcelle Danelon
• Grantee: Beatriz Aiub Trajano Silveira
• Host Institution: Universidade de Ribeirão Preto (UNAERP). Campus Ribeirão Preto. Ribeirão Preto , SP, Brazil

Abstract

Dental caries is conceptualized as a multifactorial, biofilm-sugar-dependent disease. The use of phosphate releasing agents and nanoparticles has raised great interest in the optimization of restorative materials aiming to potentiate their effects in caries control, as well as to improve their mechanical and bioactive properties, thus returning oral health to the individual. This study aims to evaluate the effect of incorporation of zinc oxide nanoparticles (ZnONPs) and sodium trimetaphosphate microparticles (TMP) in resin-modified glass ionomer cement (RGIC) on the physical-mechanical properties. Specimens will be made of each material (n=6): 1) RGIC without ZnONPs/TMP (Control); 2) RGIC with 1.0 % ZnONPs; 3) RGIC with 2.0% ZnONPs; 4) RGIC with 14.0% TMP; 5) RGIC with 1.0% ZnONPs and 14.0% TMP and 6) RGIC with 2.0% ZnONPs and 14.0% TMP (% m/m). The physical-mechanical properties of the RGIC will be determined: Diametric tensile strength, Compressive strength, Material hardness and Surface roughness. For statistical analysis, the values of the physical-mechanical tests will be considered as variables (tensile strength - MPa, compressive strength - MPa, material hardness - KHN and surface roughness - RS). The data will be submitted to normality and homoscedasticity tests to apply the statistical analysis best suited to the data distribution. The statistical program Sigmaplot® for Windows version 12.0 will be used, with significance at the 5% level.

Scientific publications

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

MENEZES, LETICIA GONCALVES OLIVEIRA; SILVEIRA, BEATRIZ AIUB TRAJANO; RAUCCI, LARISSA MOREIRA SPINOLA DE CASTRO; MARTORANO, ANTONIO SECCO; DE OLIVEIRA, PAULO TAMBASCO; ARAI, MARYLYN SETSUKO; DE CAMARGO, ANDREA SIMONE STUCCHI; HANNIG, CHRISTIAN; STERZENBACH, TORSTEN; BRIGHENTII, FERNANDA LOURENCAO; et al. Functional glass ionomer cement modified with phosphate and zinc oxide nanoparticles: in vitro insights into physicomechanical behavior, cytotoxicity and antimicrobial activity. Journal of Dentistry, v. 165, p. 10-pg., 2025-12-23. (21/10742-0, 22/08068-2)