Assessment of infants and young children exposure to dietary mycotoxins in Ribeirão Preto/SP

• Grant number: 22/03952-1
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: May 01, 2022
• End date: April 30, 2026
• Field of knowledge: Agronomical Sciences - Food Science and Technology
• Principal Investigator: Carlos Augusto Fernandes de Oliveira
• Grantee: Sher Ali
• Host Institution: Faculdade de Zootecnia e Engenharia de Alimentos (FZEA). Universidade de São Paulo (USP). Pirassununga , SP, Brazil
• Associated research grant: 19/21603-1 - Biomarker approaches for assessing the early life exposure to multiple mycotoxins in the diet, AP.TEM

Abstract

The aim of the project is to assess the exposure of infants (e 1 year and < 2 years old), preschoolers (e2 and < 6 years old), schoolchildren (e 6 years and < 10 years old) and adolescents (e 10 years and < 19 years old) from Ribeirão Preto/SP to multiple mycotoxins in the diet using food data and biomarkers in urine, and characterize the associated risk. The research protocol was approved by the Research Ethical Committee of Ribeirão Preto Medical School of the University of São Paulo (Review no. 4.690.995). Multiple mycotoxin determination in the different food types consumed by children and in children's urine will be performed by liquid chromatography coupled to tandem mas spectrometry, using validated analytical methods. The data obtained in foods and urine will be used in the exposure assessment based on estimated intake through food (indirect approach) and through urine biomarkers (direct approach), aiming at the risk characterization associated to dietary mycotoxins. (AU)

Scientific publications

(21)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

NAEEM, IQRA; ISMAIL, AMIR; RIAZ, MUHAMMAD; AZIZ, MUBASHIR; AKRAM, KASHIF; SHAHZAD, MUHAMMAD A.; AMEEN, MAVRA; ALI, SHER; OLIVEIRA, CARLOS A. F.. Aflatoxins in the rice production chain: A review on prevalence, detection, and decontamination strategies. Food Research International, v. 188, p. 20-pg., 2024-05-09. (22/03952-1)

SAFAVIZADEH, VAHID; SHER, ALI; DE OLIVEIRA, CARLOS AUGUSTO FERNANDES; MOORE, MATTHEW; GHASEMLOU, MEHRAN; NADERI-MANESH, HOSSEIN; NEMATI, MAHBOOB; NOKHODCHI, ALI; ROSTAMI, MOHAMMADREZA; TAHERGORABI, REZA. The occurrence of tenuazonic acid in food products: a systematic review. Toxin Reviews, v. 43, n. 4, p. 10-pg., 2024-08-16. (22/03952-1)

NASIR, USAMA; ISMAIL, AMIR; RIAZ, MUHAMMAD; RAZZAQ, KASHIF; MAHMOOD, ASIF; AL MASRY, WAHEED; LATIF, MUHAMMAD; ASLAM, FARWA; ALI, SHER; OLIVEIRA, CARLOS A. F.. Artificial Ripening of Mangoes Marketed in Pakistan: Impact on Physicochemical Properties and Occurrence of Potentially Toxic Elements. JOURNAL OF FOOD SAFETY, v. 45, n. 3, p. 9-pg., 2025-06-01. (22/03952-1)

FREIRE, LUCAS GABRIEL DIONISIO; ALI, SHER; DE OLIVEIRA, CARLOS AUGUSTO FERNANDES. Evaluation of Adsorbent's Efficiency by Using Biomarker Approaches in Farm Animals: A Systematic Review. APPLIED SCIENCES-BASEL, v. 12, n. 24, p. 13-pg., 2022-12-01. (19/21603-1, 22/05066-9, 22/03952-1)

PIRES, ROGERIO CURY; CALUMBY, JULIA DA COSTA; ROSIM, ROICE ELIANA; PIRES, ROGERIO D'ANTONIO; BOROWSKY, ALINE MOREIRA; ALI, SHER; DE PAIVA, ESTHER LIMA; SILVA, RAMON; PIMENTEL, TATIANA COLOMBO; DA CRUZ, ADRIANO GOMES; et al. Evaluation of Ability of Inactivated Biomasses of Lacticaseibacillus rhamnosus and Saccharomyces cerevisiae to Adsorb Aflatoxin B₁ In Vitro. FOODS, v. 13, n. 20, p. 12-pg., 2024-10-01. (22/03952-1, 19/21603-1, 22/15367-6, 22/07439-7)

DE PAIVA, ESTHER LIMA; ALI, SHER; VASCO, ELSA REIS; ALVITO, PAULA CRISTINA; OLIVEIRA, CARLOS AUGUSTO FERNANDES. Bioaccessibility data of potentially toxic elements in complementary foods for infants: A review. Food Research International, v. 174, p. 11-pg., 2023-10-17. (22/03952-1, 22/15367-6)

NAEEM, IQRA; ISMAIL, AMIR; GONG, YUN YUN; RIAZ, MUHAMMAD; HAMEED, ANEELA; AZIZ, MUBASHIR; MAHMOOD, ASIF; AL MASRY, WAHEED; LATIF, MUHAMMAD; ALI, SHER; et al. Aspergillus spp and aflatoxins in Pakistani rice: A case study on the decontamination effect of accelerated aging and improved storage practices. Toxicon, v. 266, p. 8-pg., 2025-08-08. (22/03952-1)

ALI, SHER; FRANCO, BRUNA BATTAGLINI; REZENDE, VANESSA THEODORO; ULLAH, SANA; WAHAB, NIDA; FREIRE, LUCAS GABRIEL DIONISIO; ROSIM, ROICE ELIANA; TONIN, FERNANDO GUSTAVO; CORASSIN, CARLOS HUMBERTO; DEL CIAMPO, LUIZ ANTONIO; et al. Children's exposure to mycotoxins and risk characterization using urinary biomarkers in Sao Paulo, Brazil. Environmental Pollution, v. 385, p. 12-pg., 2025-09-26. (23/05989-2, 22/01920-5, 22/05066-9, 22/03952-1, 19/21603-1)

BASSO, AMANDA BEZERRA GONCALVES; ALI, SHER; CORASSIN, CARLOS HUMBERTO; ROSIM, ROICE ELIANA; DE OLIVERIA, CARLOS AUGUSTO FERNANDES. Individual and combined decontamination effect of fermentation and ultrasound on aflatoxin B1 in wheat-based doughs: a preliminary study. QUALITY ASSURANCE AND SAFETY OF CROPS & FOODS, v. 15, n. 3, p. 8-pg., 2023-01-01. (22/03952-1)

SADIGHARA, PARISA; SALAR-AMOLI, JAMILEH; BARIN, ABBAS; ALI, SHER; OLIVEIRA, CARLOS AUGUSTO FERNANDES. Thiamine Mitigates the Toxicity of Methylmercury in Cultured Fetal Fibroblast Cell Lines. Cell Biochemistry and Biophysics, v. N/A, p. 7-pg., 2025-07-21. (22/03952-1)

ULLAH, SANA; ALI, SHER; ATIF, MUHAMMAD; ULLAH, MUHIB; NABI, GHULAM; FREIRE, LUCAS GABRIEL DIONISIO; KAMIMURA, ELIANA SETSUKO; NEJAD, AMIR SASAN MOZAFFARI; DE OLIVEIRA, CARLOS AUGUSTO FERNANDES. The potential influence of food additives and contaminants on the gut microbiota: A comprehensive review. Food and Chemical Toxicology, v. 206, p. 22-pg., 2025-09-30. (22/05066-9, 22/03952-1, 19/21603-1, 23/05989-2)

FREIRE, LUCAS GABRIEL DIONISIO; ALI, SHER; DE OLIVEIRA, CARLOS AUGUSTO FERNANDES. Effectiveness of biological decontamination methods to reduce the toxic effects of mycotoxins in animal models: a review. Toxin Reviews, v. 43, n. 4, p. 19-pg., 2024-06-25. (22/03952-1, 19/21603-1, 22/05066-9)

SILVA, ISABELA MARIA DE MOURA; DA CRUZ, ADRIANO GOMES; ALI, SHER; FREIRE, LUCAS GABRIEL DIONISIO; FONSECA, LUZIANNA MACEDO; ROSIM, ROICE ELIANA; CORASSIN, CARLOS HUMBERTO; DE OLIVEIRA, RODRIGO BARBOSA ACIOLI; DE OLIVEIRA, CARLOS AUGUSTO FERNANDES. Incidence and Levels of Aflatoxin M-1 in Artisanal and Manufactured Cheese in Pernambuco State, Brazil. TOXINS, v. 15, n. 3, p. 10-pg., 2023-03-01. (22/03952-1, 19/21603-1)

ALI, SHER; BADSHAH, GUL; ALI, UMAR; AFRIDI, MUHAMMAD SIDDIQUE; SHAMIM, ANWAR; KHAN, AJMIR; FELIPE SOARES, FREDERICO LUIZ; ALENCAR MENEZES, LEOCILEY ROCHA; REZENDE, VANESSA THEODORO; BARISON, ANDERSSON; et al. Leaf tissue metabolomics fingerprinting of Citronella gongonha Mart. by H-1 HR-MAS NMR. SCIENTIFIC REPORTS, v. 12, n. 1, p. 13-pg., 2022-10-21. (22/03952-1)

REZENDE, VANESSA THEODORO; NACIMENTO, RAFAEL ARAUJO; ALI, SHER; RODRIGUES, GUSTAVO ROBERTO DIAS; ROMANELLI, THIAGO LIBORIO; CYRILLO, JOSLAINE NOELY DOS SANTOS GONSALVES; BONAUDO, THIERRY; LESCOAT, PHILIPPE; GAMEIRO, AUGUSTO HAUBER. Understanding nitrogen dynamics in the Brazilian beef industry: A comprehensive decadal analysis. Science of The Total Environment, v. 921, p. 12-pg., 2024-02-26. (22/03952-1)

ALI, SHER; REZENDE, VANESSA THEODORO; ULLAH, SANA; DE PAIVA, ESTHER LIMA; TONIN, FERNANDO GUSTAVO; ABDULLAH; CORASSIN, CARLOS HUMBERTO; DE OLIVEIRA, CARLOS AUGUSTO FERNANDES. Food processing and challenges in the food production and quality: The foodomics approach. FOOD BIOSCIENCE, v. 56, p. 13-pg., 2023-10-09. (22/03952-1, 19/21603-1, 22/15367-6, 23/05989-2)

ALI, SHER; FREIRE, LUCAS GABRIEL DIONISIO; REZENDE, VANESSA THEODORO; NOMAN, MUHAMMAD; ULLAH, SANA; ABDULLAH; BADSHAH, GUL; AFRIDI, MUHAMMAD SIDDIQUE; TONIN, FERNANDO GUSTAVO; DE OLIVEIRA, CARLOS AUGUSTO FERNANDES. Occurrence of Mycotoxins in Foods: Unraveling the Knowledge Gaps on Their Persistence in Food Production Systems. FOODS, v. 12, n. 23, p. 17-pg., 2023-12-01. (22/03952-1, 22/05066-9, 23/05989-2)

ALI, SHER; FRANCO, BRUNA BATTAGLINI; REZENDE, VANESSA THEODORO; FREIRE, LUCAS GABRIEL DIONISIO; DE PAIVA, ESTHER LIMA; HAIKAL, MARIA CLARA FOGACIO; GUERRA, ELOIZA LEME; ROSIM, ROICE ELIANA; TONIN, FERNANDO GUSTAVO; FERRAZ, IVAN SAVIOLI; et al. Exposure assessment of children to dietary mycotoxins: A pilot study conducted in Ribeirao Preto, Sao Paulo, Brazil. Food Research International, v. 180, p. 9-pg., 2024-02-09. (22/03952-1, 22/05066-9)

AFRIDI, MUHAMMAD SIDDIQUE; SALAM, ABDUL; ALI, SHER; SUMAIRA; TERRA, WILLIAN CESAR; ALI, BABER; MUNEER, MUHAMMAD ATIF; SANTOYO, GUSTAVO. Harmonizing traditional and biotechnological approaches to engineer crop microbiomes: Enhancing resilience optimization. BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY, v. 62, p. 25-pg., 2024-12-01. (22/03952-1)

DE OLIVEIRA, AMANDA CRISTINA DIAS; ALI, SHER; CORASSIN, CARLOS HUMBERTO; ULLAH, SANA; PEREIRA, KARINA NASCIMENTO; WALSH, JAMES LEON; HOJNIK, NATASA; DE OLIVEIRA, CARLOS AUGUSTO FERNANDES. Application of cold atmospheric plasma for decontamination of toxigenic fungi and mycotoxins: a systematic review. FRONTIERS IN MICROBIOLOGY, v. 15, p. 20-pg., 2025-01-03. (24/00896-9, 23/05989-2, 22/03952-1)

ULLAH, SANA; ALI, SHER; REZENDE, VANESSA THEODORO; NABI, GHULAM; TONIN, FERNANDO GUSTAVO; DE OLIVEIRA, CARLOS AUGUSTO FERNANDES. Global occurrence and levels of mycotoxins in infant foods: A systematic review (2013-2024). FOOD CONTROL, v. 171, p. 17-pg., 2025-01-07. (23/05989-2, 19/21603-1, 22/03952-1)