Preparation of guanidine derivatives for sar studies against parasitic diseases

• Grant number: 22/12360-0
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• Start date: October 01, 2022
• End date: February 28, 2027
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Igor Dias Jurberg
• Grantee: Ronei Messias Silva Souza
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 19/17721-9 - The role of Chemistry in holobiont adaptation, AP.TEM

Abstract

In this work, we will be interested in the synthesis of several guanidine derivatives containing 1, 2 or 3 fused cycles, whose structures are inspired in the structures of batzelladine alkaloids. These molecules will be tested against parasitic diseases. (AU)