| Grant number: | 23/06121-6 |
| Support Opportunities: | Scholarships in Brazil - Doctorate (Direct) |
| Start date: | January 01, 2024 |
| End date: | September 14, 2027 |
| Field of knowledge: | Health Sciences - Physiotherapy and Occupational Therapy |
| Principal Investigator: | Luiz Fernando Approbato Selistre |
| Grantee: | Giovanna Laura Neves Antonio Gaban |
| Host Institution: | Centro de Ciências Biológicas e da Saúde (CCBS). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil |
| Associated scholarship(s): | 24/05479-7 - Can pain processing at baseline predict changes in pain and functional capacity after 8-week of exercise in individuals with low back pain?, BE.EP.DD |
Abstract Individuals with chronic neck pain may have changes in central pain processing. The literature recommends approaches such as therapeutic exercises although the evidence for exercise-induced hypoalgesia (EIH) in this population is limited, inconclusive and of low methodological quality. It is known that EIH can be influenced by the type of exercise and by the involvement of painful (specific exercises) or non-painful (non-specific exercises) muscles. Furthermore, there is no evidence whether an intervention protocol of these exercises can modulate EIH andpain processing over the time. For these reasons it is critical to compare the acute and long-term effects of specific and non-specific exercise protocols on pain processing. This information will help the development of strategies that optimize therapeutic exercise prescriptions with the objective of pain relief and decrease of pain exacerbation after an exercise session, thus increasing adherence to long-term rehabilitation programs. Objectives: To compare the acute and long-term effect of two exercise protocols (specific and non-specific) on pain processing in subjects with chronic non-specific neck pain. Methodology: Single-blind randomized controlled clinical trial. Ninety-four participants between 18 and 65 years of age who have had non-specific neck pain for more than 3 months will be recruited. They will be randomized and allocated into two groups (specific exercises (SE) and non-specific exercises (NSE)) and will receive interventions acutely (a single session) and long-term, at home twice a week for 8 weeks . Both protocols are divided into 2 progressive and individualized phases. The primary outcomes will be: pain intensity at rest and during movement using the numerical pain rating scale, pressure pain threshold and exercise-induced hypoalgesia. Secondary outcomes will be: temporal summation, conditioned pain modulation, Neck Disability Index, Global Perception of Change Scale and adherence to exercises. Assessments will be performed at baseline, after 8 weeks of intervention and at 6-month follow-up. Statistical analysis: Analysis of treatment effects will follow the principles of intention-to-treat analysis. In order to compare the acute and long-term effects of the interventions, mixed models of analysis of variance (ANOVA) will be used, with interaction between groups (SE and NSE) and time (pre, post intervention of 8 weeks and follow-up of 6 months ). | |
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