Assessment of SARS-CoV-2 infection and coronavirus vaccine response in transplant recipients, dialysis patients and healthcare workers

• Grant number: 23/13854-0
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: November 01, 2023
• End date: October 31, 2025
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Principal Investigator: Jose Osmar Medina de Abreu Pestana
• Grantee: Roberto Matias Souza
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil
• Associated research grant: 21/13680-6 - Evaluation of SARS-CoV-2 infection and Coronavirus vaccine response in transplant recipients, dialysis patients, and health workers, AP.TEM

Abstract

It is known that the acute disease caused by the new coronavirus, SARS-CoV-2, is characterized by multisystemic involvement. Post-COVID syndrome, which affects around 10% of patients with COVID-19 in the general population, and defined as the persistence of symptoms three months after infection. Recipients of solid organ transplants make chronic use of immunosuppressive medication, which alters the immune response to infections in general. There are no specific studies regarding post-COVID syndrome in this population.