Validation of two methods of detection and clinical measurement of erosive tooth wear: A prospective Coort study

• Grant number: 24/01944-7
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: January 01, 2025
• End date: December 31, 2028
• Field of knowledge: Health Sciences - Dentistry - Dental Clinics
• Principal Investigator: Taís Scaramucci Forlin
• Grantee: Claudia Allegrini Kairalla
• Host Institution: Faculdade de Odontologia (FO). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

This study will be an observational, longitudinal and prospective clinical trial. The aim of this study is to evaluate the predictive and construct validity of two methods, Basic Erosive Wear Examination index (BEWE index) and 3D intraoral scanner for clinically detect, measure and monitor the progression of erosive tooth wear (ETW) lesions in patients with high risk for the condition compared to patients who are not part of any risk group over time, seeking early clinical identification of the existence of a high rate of progression of ETW, distinguishing between physiological and pathological EDD rates. The recruitment of volunteer patients will be carried out, and after that the volunteer will answer a questionnaire regarding their eating habits, behaviors, general and oral health status, as well as their self-perception of ETW and impacts on their quality of life. Volunteers who present risk conditions for ETW, such as gastric disorders (gastroesophageal reflux, recurrent vomiting and heartburn), excessive consumption of acid foods and beverages, and presence of dental lesions characterizing erosive dental wear. Volunteers who present high risk ETW conditions will be allocated into the group of patients of high risk, and volunteers that do not present these conditions will be allocated into the group without risk. The monitoring of ETW will be carried out in the first visit, after 3 and 6 months, 1 and 2 years, visually accessed through the BEWE index. They will be also volumetric accessed, through the superimposition of 3D images of the patient's study model, which will be performed with VIRTUO Vivo intraoral 3D scanner (Straumman Digital Solutions) and with WearCompare alignment software (School of Dentistry, University of Leeds, Leeds, UK) (www.leedsdigitaldentistry.com/WearCompare). The predetermined premise is that over the monitored time more wear will be detected and measured in patients in the risk group than in patients who are not in the risk group. The data will be evaluated with the appropriate statistical tests, considering (=0.05).