Development of mesoporous silica nanoparticles functionalized with bioactive compounds for application in soybean crops

• Grant number: 25/15564-4
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• Start date: January 12, 2026
• End date: January 11, 2027
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Marco Aurelio Zezzi Arruda
• Grantee: Cristiane Renata Schmitt
• Supervisor: Carlos Lodeiro-Espino
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Institution abroad: Universidade Nova de Lisboa, Portugal
• Associated to the scholarship: 24/08113-3 - Biosynthesis of Cu and bimetallic Cu and Ag nanoparticles and their uses in the cultivation of embryogenic soybean callus, BP.PD

Abstract

Contemporary agriculture demands innovative solutions that combine productivity, sustainability, and reduced agrochemical use. In this context, the use of nanomaterials applied to the controlled release of bioactive substances has emerged as a promising strategy for increasing the physiological efficiency of crops, especially under conditions of biotic and abiotic stress. Mesoporous silica nanoparticles (MSNs) have ideal structural properties for this purpose, such as high surface area, ordered porosity, and ease of functionalization. This project proposes the synthesis and characterization of MSNs functionalized with five compounds of agronomic interest: chitosan, glycine, melatonin, proline, and salicylic acid. These agents are recognized for their antioxidant, osmoprotective, and plant defense-inducing properties, and are especially relevant for soybean (Glycine max) cultivation. The nanoparticles will be obtained using the modified Stöber method and characterized by FTIR, TGA, XRD, BET, DLS, zeta potential, and electron microscopy (TEM/SEM). The project will be developed in partnership with an international research group with extensive experience in the synthesis and application of functional nanomaterials. The proposal aims to lay the foundation for future agronomic applications of the developed formulations, contributing to safer and more technologically advanced alternatives for the physiological management of agricultural crops.