Phytochemical Study and Evaluation of Mutagenic, Antimutagenic and Acetylcholinesterase Enzyme Inhibitory Potential of Roupala montana.

• Grant number: 09/15218-6
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: December 01, 2009
• End date: November 30, 2011
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Ana Helena Januário
• Grantee: Nayanne Larissa Cunha
• Host Institution: Pró-Reitoria Adjunta de Pesquisa e Pós-Graduação. Universidade de Franca (UNIFRAN). Franca , SP, Brazil

Abstract

Roupala montana Aubl. belongs to Proteaceae family, being one of the vegetal native species from "cerrado", which constitutes the flora of the ecological Station of Jataí -SP. This " cerrado" region has been selected for study in the Research Project "Phytochemical Study and Evaluation of the Antimalarial, Antimicrobial and Acetylcholinesterase Inhibition Activities from The São Paulo State Cerrado Native Species" (Fapesp Process n. 2008/01268-9). However for the R. montana species the chemical study as well the evaluation of its biological potential are unpublished. Thus, the aim of this Cientific Iniciation Project is to carry out phytochemical studies of the aerial parts of R. montana, and the evaluation of its mutagenic, antimutagenic and acetylcholinesterase enzyme inhibitory potential seeking to pin-point the chemical constituents present in R. montana responsible for these activities.