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Comparative evaluation of an experimental dentifrice with bioactive micron-size particles (biosilicate) on remineralization of bovine enamel

Grant number: 09/00514-9
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): April 01, 2009
Effective date (End): March 31, 2010
Field of knowledge:Health Sciences - Dentistry
Principal Investigator:Camila Tirapelli
Grantee:Ivan Lobo Gava
Home Institution: Faculdade de Odontologia de Ribeirão Preto (FORP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
Associated research grant:07/08179-9 - Kinetic processes in glasses and glass ceramics, AP.TEM


Objective: to evaluate comparatively the remineralizing and abrasive effect of an experimental dentifrice containing micron-size bioactive particles of Biosilicate®, one fully crystallized bioactive glass-ceramic. Materials and Methods: the factors under study are the dentifrices: Groups: G1- control (distilled water); G2- experimental dentifrice containing 7,5% of micron-size particles of Biosilicate®; G3- experimental dentifrice without the micron-size particles of Biosilicate®; G4- market dentifrice Sorriso® (1500 ppm of MFP) G5- market dentifrice Colgate Baby® (500 ppm of NAF). Dental bovine enamel blocks (4x4x3mm) will be the specimens (n=10 per group). The variables analyzed to evaluate the remineralization performance are Fourrier transformed infra-red spectroscopy (FTIR), scanning electron microscopy (SEM) and microhardness test before and after remineralization and demineralization cicles, which will occur three times per day, during 10 days, in order to simulate the dynamic process of change of pH along the hole day. To test the abrasivity, the specimens will be evaluated regarding wear resistance when brushed with the dentifrices tested (International Organization for Standardization- ISO:14569-1/1999). Analyses of the results: obtained data from the microhardness and abrasivity testes will be analyzed under properly statistics tests.