Evaluation of physical-chemical properties of experimental infiltrants chlorhexidine-added

Author(s)

Luciana Tiemi Inagaki

• Document type: Doctoral Thesis
• Press: Piracicaba, SP.
• Institution: Universidade Estadual de Campinas (UNICAMP). Faculdade de Odontologia de Piracicaba
• Defense date: 2016-01-15

Examining board members

Fernanda Miori Pascon; Cássia Cilene Dezan Garbelini; Ana Flavia Sanches Borges; Américo Bortolazzo Correr; Marinês Nobre dos Santos

• Advisor: Fernanda Miori Pascon

Abstract

This study evaluated the chlorhexidine (CHX) and monomeric base effects in physical-chemical properties of experimental resin materials. This thesis was divided in two chapters. Monomeric blends with two concentrations of CHX were prepared: TEGDMA, TEGDMA/0.1%CHX, TEGDMA/0.2%CHX, TEGDMA/UDMA, TEGDMA/UDMA/0.1%CHX, TEGDMA/UDMA/0.2%CHX, TEGDMA/BisEMA, TEGDMA/BisEMA/0.1%CHX e TEGDMA/BisEMA/0.2%CHX. Icon® infiltrant was used as commercial control group. The Chapter 1 evaluated sorption/solubility (SS), softening, elastic modulus (EM) and flexural strength (FS) of nine experimental blends. The SS was accomplished according to ISO 4049, using disks with 7 mm of diameter x 1 mm of thick (n=5); for softening, disks with 5 mm of diameter x 1 mm of thick were used (n=10); for EM and FS bars with 7 mm x 2 mm x 1 mm were used (n=10). The data were submitted to ANOVA and Tukey test (?=5%). The CHX presence, regardless concentration, did not interfere in SS, EM and FS. For sorption, the TEGDMA blends showed the highest averages and they were different than control (p<0.01). The TEGDMA/BisEMA blends presented the lowest averages and they were not different than control (p>0.05). TEGDMA/UDMA based blends showed intermediate values and they were different than control (p<0.01). Concerning solubility, Icon® was the most soluble when it was compared with experimental blends (p<0.01). UDMA and BisEMA based blends were less soluble and they did not differ statistically between each other (p>0.05). About EM, all blends were different than control (p<0.01), which show the lowest average. UDMA blends showed the highest average, and they did not differ between each other and from TEGDMA/BisEMA (p>0.05). For FS, the blends with UDMA and BisEMA were different than control (p<0.01), showing the highest average. TEGDMA blends and Icon® were not different between each other (p>0.05), with the lowest values of FS. For softening, TEGDMA/UDMA/0.1%CHX showed the highest average and it was different than experimental blends (p<0.05), but it was not different than control (p>0.05). The Chapter 2 evaluated using non-contact profilometer the surface roughness in 2D (Ra) and in 3D (Sa), and the material loss after mechanical wear by three-body (n=8). For this, the blends evaluated were: TEGDMA/0.2%CHX; TEGDMA/UDMA/0.2%CHX; TEGDMA/BISEMA/0.2%CHX and the commercial control (Icon®). The data were submitted to ANOVA for repeated measures, one-way ANOVA and Tukey and simple linear regression (?=5%). After mechanical wear, the TEGDMA/UDMA/0.2%CHX blend showed the lowest values for roughness (Ra and Sa) and for material loss, and it was different than control (p<0.01). The blend TEGDMA/BisEMA/0.2%CHX showed the highest mechanical wear and it was different than control (p<0.01). There was significant association (p<0.01) between Ra and Sa roughness (R2=74.56%). In front of the results it could be concluded that the CHX did not affect negatively the SS, EM and FS properties. The presence of 0.1% of CHX affected UDMA blend softening. The blends monomeric base influenced the properties evaluated in Chapter 1 and 2. The TEGDMA/UDMA based blends showed the better results for properties evaluated, except for softening. Superficial roughness in Ra and Sa showed association (AU)

• FAPESP's process: 11/22149-0 - ASSESSMENT OF RESISTANCE TO CHEMICAL, MECHANICAL AND BIOLOGICAL DEGRADATION OF EXPERIMENTAL INFILTRANTS FOLLOWED SOLUBILITY AND CYTOTOXICITY TESTS
• Grantee: Luciana Tiemi Inagaki
• Support Opportunities: Scholarships in Brazil - Doctorate