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METHOD FOR SELECTING TICK ANTIGENS AND ANTIGENIC COMPOSITIONS AGAINST TICKS
Isabel Kinney Ferreira de Miranda Santos; José Marcos Chaves Ribeiro; Beatriz Rossetti Ferreira; Cecília José Veríssimo; Lucinda Giampietro Brandao; Sandra Regina Costa Maruyama; Elen Anatriello; Gustavo Rocha Garcia; Daniela Dantas Moré; Jesus Gilberto Valenzuela
The present invention relates to a method for selecting tick antigens, comprising the following steps: producing a tick transcriptome; synthetising the proteins; selecting the antigenic proteins; assessing the biological importance of the selected proteins; cloning and subcloning the DNA sequences relating to the selected proteins; synthetising antigens against ticks; and also, to antigenic compositions against ticks useful for mammals.