Physicist (UNESP, 2002), Master/Doctor in Medical Physics (USP, 2005 and 2009, respectively), Post-Doctor (USP, 2010) and Associate Professor in Biomaterials Engineering (UNESP, 2017). Professor at UNESP since 2010 researching in the areas of Biomaterials, Bioengineering, Biomedical Engineering, Biotechnology. Has experience with FTIR, mechanical resistance, SEM, AFM, spectrophotometry, spectrofluorimetry, EPR, etc. techniques. It acts mainly in the controlled release of bioactive compounds by polymer matrices, especially by natural latex membranes. The Bioengineering and Biomaterials Group, without any coordination, applies latex membranes in cell culture (in vitro), animals (pre-clinical) and humans (clinical). In addition, he has experience in microfluidics, organs-on-a-chip, spheroids, organoids, microfabrication and 3D bioprinting (encapsulation of cells in hydrogels). (Source: Lattes Curriculum)
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Natural rubber latex membranes of Hevea brasiliensis has been used as a dressing for cutaneous ulcers. Moreover, latex membrane also has been broadly used in controlled drug release systems development. Barbatimam have several medically useful properties, such as anti-inflammatory, antimicrobial, antioxidant and healing properties, associated to high tannin contents. Its organic fraction …
Multi-User Equipment approved in grant 2014/17526-8: Electron Paramagnetic Resonance (EPR) spectrometer - X Band is the most straightforward-to-use technique for studying free radicals and other paramagnetic species and has therefore established itself in biomedical research and for clinical applications. In additional, this technique also have been extensively employed in many areas in p…
Natural Rubber Latex (NRL) has been proven excellent for its biocompatibility and ability to stimulate angiogenesis, cellular adhesion and the formation of extracellular matrix, promoting the replacement and regeneration of tissue. The aim of this project is to incorporate the extracts of Stryphnodendron sp, Casearia sylvestris Swartz and Cordia verbenacea in latex biomembranes and to stu…
(Only some records are available in English at this moment)
A new and constantly growing technological segment is the development of coatings for fresh fruits with conservation and protection properties and capable of increasing their shelf life. Biodegradable polymers are promising to this appliance, considering the current urge in sustainability and environmental preservation. The main goal of this project is to develop a coating for fresh fruit…
Magnetic nanoparticle mediated intracellular hyperthermia is promising in therapies against cancers, both for generating heat only in tumors, with the ability to accumulate itself at the desired local, and for healthy cells to sit heat out more than tumors, wherein at a temperature about 42ºC, cancer cells lysis occurs while healthy cells remain viable. Thus, it promotes the possible cure…
The natural rubber latex (NRL) extracted from Hevea brasiliensis is widely used in industry and has shown good results in biomedical applications. Due its biocompatibility and ability to induce angiogenesis and bone regeneration, NRL can be used as medical prosthesis and grafts. Therefore NRL can be applied as a matrix of a controlled release system, allowing drugs to reach their target a…
(Only some records are available in English at this moment)
Evaluation of cytotoxicity of new drugs, compounds and biomaterials using two-dimensional cell culture is an interesting alternative to reduce the use of animals. However, growing cells in flat layers on plastic surfaces does not accurately model the in vivo state. So, organs-on-chips present an ideal microenvironment to mimic a tissue/organ human-specific. The objective of this work is t…
Sialorrhea is a disorder which can promote an increased saliva production and usually occurs along with severe neurological disorders. This disorder can be treated through administration of scopolamine, an anticholinergic agent commonly used for nausea and seasickness treatment. The best route of administration for scopolamine is the transdermal application since it minimizes the occurren…
Natural Rubber Latex (NRL), extracted from the Hevea brasiliensis, has been of great importance due to latex ability to stimulate angiogenesis, cell adhesion and the formation of extracellular matrix. However, the biodegradability of latex is not significant when compared to other polymers used for the development of materials with biomedical applications, which is a major factor for its …
(Only some records are available in English at this moment)
| 4 / 4 | Completed research grants |
| 17 / 17 | Completed scholarships in Brazil |
| 4 / 4 | Completed scholarships abroad |
| 25 / 25 | All research grants and scholarships |
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CV Lattes
ORCID