graduation at Ciência da Computação from Universidade de São Paulo (2003) and doctorate at Bioinformática from Universidade de São Paulo (2007). Has experience in Biochemistry, acting on the following subjects: astrocytomas, sage, access, normalization and bioinformatica. (Source: Lattes Curriculum)
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Trypanosoma is a genus, which contains two pathogenic species to human beings: Trypanosoma brucei and Trypanosoma cruzi. These two species are relevant in terms of economy, welfare, and health. The metabolism of the different stages of both pathogenic trypanosomatids has been a matter of study not only because of their relevance for the economy and human health, but also because of their …
From the earliest single-neuron recording experiments through the multivariate functional magnetic resonance imaging (fMRI), one of the predominant themes in neuroscience has been the development of brain reading approaches and human-machine interfaces (HMI). Although decades of research, in both fields, advances are unsatisfactory, far from being useful in real-life tasks. Researchers of…
The CAPOEIRA project will cover theoretical computer science (essentially graph theory), mathematics (combinatorics, statistics, and probability), and the development of algorithms to address various biological questions, in particular, the intra and cross-species interactions, which have implications in all aspects of life sciences, including health, ecology, and environment. Two main ge…
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Recently it has been demonstrated that the structure of functional brain and gene regulatory networks are more adequate to characterize biological organisms states than the individual analysis of their parts. Besides, it is known that such networks are not exactly equal (isomorphic) even by comparing individuals belonging to the same group due to intrinsic variability. Thus, approaches ba…
The understanding of the biological mechanisms underlying human diseases is one of the main challenges in biological sciences. Although several efforts, the large number of heterogeneous factors that influence the genesis of a disease makes it a very hard task. One of the challenges consists in understanding diseases by developing methods to statistically analyze and computationally manip…
Wiener (1956) and Granger (1969) have introduced an intuitive concept of causality (Granger causality) between two variables, which is based on the idea that an effect never occurs before its cause. Although Granger causality is not "effective causality" in the Aristothelic sense, this concept is useful to infer directionality and information flow in data sets. Later, Geweke (1984) genera…
Evidence suggests that emotions/brain states involve patterns of behavior, physiological, and neural activation. Some emotions have been successfully classified from peripheral physiological responses, bodily activation patterns (Kragel and Labar, 2015; Kreibig et al., 2007; Nummenmaa et al., 2014; Hietanen et al. 2016; Siegel et al., 2018), and subjective feelings (Saarimäki et al., 2018…
One of the bottlenecks of the methods for network statistics is the high computational cost to compute the spectral distribution (methods for parameter estimation, model selection, and comparison tests, for instance, are based on the spectral distribution of the graph) (Fujita et al., 2016; Takahashi et al., 2012). Currently, to estimate the spectral distribution of the graph, we compute …
Over the last years, several real-world data have been modeled as graphs. Consequently, both the number of graphs and also their sizes have been increasing. Nowadays, it is possible to find very big graphs (millions of vertices). In this context, the development of efficient computational methods to analyze big graphs and the training of personnel able to use these computational tools bec…
The high number of deaths due to breast cancer shows the importance of the studies carried out in the area. Among the molecular subtypes of breast cancer, the World Health Organization associates triple-negative with the more aggressive form and, since it does not have specific treatments, presents the worst prognoses. Given the importance of cancer studies, multi-omic databases provide a…
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There are at least three main reasons to the lack of reduction of the number of people with alcohol abuse, major depression, and attention deficit hyperactivity disorders (ADHD), namely: (i) the late diagnosis at a time when psychopathology is already well advanced, (ii) a classification based on patient self-report and behavioral observation, which do not reflect the underlying biologica…
Graph theory has applications in several domains. For example, in molecular biology graphs may represent protein-protein interaction networks or gene regulatory networks; and in neuroscience they are used to study brain functional networks. As real world networks usually present intrinsic fluctuations (for example, brain functional networks vary across time and individuals under the same …
| 4 / 4 | Ongoing research grants |
| 5 / 3 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 8 / 8 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 20 / 18 | All research grants and scholarships |
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CV Lattes
ORCID