CV Lattes
ResearcherID
ORCID
Fundação Pio XII (FP). Hospital do Câncer de Barretos (Institutional affiliation for the last research proposal) Birthplace: Portugal
Dean of Graduate Studies; Executive and Scientific Director of the Teaching and Research Institute (IEP); Coordinator of the Molecular Oncology Research Center (CPOM); and Scientific Director of the Molecular Diagnostic Laboratory at the Barretos Cancer Hospital, Barretos, SP. Brazil. Invited Associate Professor at the University of Minho School of Medicine (Braga, Portugal). Extraordinary Professor, Pan African Cancer Research Institute, University of Pretoria, South Africa. Graduation in biology, University of Porto (Portuga) l; doctorate in neuro-oncology, IARC (Lyon, France); postdoctoral fellow in cancer genomics, Free University Medical Center (Amsterdam, Netherlands) and IPATIMUP (Porto, Portugal). CNPq researcher productivity 1C. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| Rare brain tumor described for first time in Brazil |
| New biomarkers help brain tumor assessment |
Gliobastomas are the most frequent and malignant brain neoplasia among the central nervous system tumors. These are incurable neoplasias, with mean survival of 13 months, and less than 2% of the patients reach 5 years post treatment. The low success in the treatment of these tumors are, in part, due to the little understanding of their molecular bases. Moreover, several in vitro studies a…
Cancer is responsible for a significant and growing number of patients worldwide, and represents the second leading cause of death in many countries. In the search for new therapies, research with natural products has emerged as an alternative and successful source in the development of potential drugs. The species Euphorbia tirucalli, popularly known as ''aveloz'' is used in folk medicin…
The Epidermal Growth Factor Receptor (EGFR) is an important protein which activation leads to the signaling of intracellular pathways that act directly on cell proliferation, migration and survival. Cetuximab (CTX), is an anti-EGFR monoclonal antibody that has been approved for the treatment of Head and Neck Squamous Cell Carcinoma (HNSCC) patients and metastatic Colorectal Cancer (mCRC).…
Glioblastoma (GBM) is a highly aggressive and invasive tumor that confers high mortality rates and low survival. The standard treatment consists of surgical resection of the tumor, accompanied by radiotherapy and chemotherapy associated with the use of temozolomide (TMZ), a DNA alkylating agent that, administered to the patient, promotes a slight increase in survival. However, GBM present…
The autophagic process is a recycling and degradation system, suggested as an important pathway of cell death in tumor cells. The autophagic pathway is connected with the endocytic pathways from the same final destination, lysosomal. Lysosomes in turn are crucial regulators of cell homeostasis, responsible for downregulate the signaling receptors and their turnover, contributing to tumor …
(Only some records are available in English at this moment)
The gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract whose prognosis of the patients is based on criteria including tumor size, mitotic index and localization. Despite of this classification, GIST progression is often inaccurate. The aim of this study is to elucidate the biological role and therapeutic potential biomarker TERT in…
Gliomas are the most frequent and malignant tumors within the Central System Nervous (CNS) tumors. They are an incurable neoplasia, with a survival average of approximately 13 months, and less than 2% of the patients survive 5 years after the treatment. The low success in the treatment of these tumors is, in part, due to the low understanding of their molecular bases. The present project …
| 1 / 1 | Ongoing research grants |
| 6 / 2 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 12 / 11 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 22 / 17 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 29 |
| Citations | 248 |
| Cit./Article | 8.6 |
| Data from Web of Science | |
BIDINOTTO, LUCAS TADEU; VEO, CARLOS A. R.; LOAIZA, EDGAR ALEMAN; RIBEIRO, GUILHERME G.; LORENZI, ADRIANA T.; REIS ROSA, LUCIANA ALBINA; DE OLIVEIRA, CRISTINA MENDES; LEVI, JOSE EDUARDO; SCAPULATEMPO-NETO, CRISTOVAM; LONGATTO-FILHO, ADHEMAR; et al. Loss of Raf kinase inhibitor protein expression is associated with human papillomavirus 16 infection in anal tumors. Oncology Letters, v. 16, n. 2, p. 1785-1790, AUG 2018. Web of Science Citations: 0. (10/16795-4, 11/08523-7)
MACKAY, ALAN; BURFORD, ANNA; CARVALHO, DIANA; IZQUIERDO, ELISA; FAZAL-SALOM, JANAT; TAYLOR, KATHRYN R.; BJERKE, LYNN; CLARKE, MATTHEW; VINCI, MARA; NANDHABALAN, MEERA; et al. Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma. CANCER CELL, v. 32, n. 4, p. 520+, OCT 9 2017. Web of Science Citations: 115. (11/08523-7, 12/08287-4)
BIDINOTTO, LUCAS TADEU; TORRIERI, RAUL; MACKAY, ALAN; ALMEIDA, GISELE CARAVINA; VIANA-PEREIRA, MARTA; CRUVINEL-CARLONI, ADRIANA; SPINA, MARIA LUISA; CAMPANELLA, NATHALIA CRISTINA; DE MENEZES, WEDER PEREIRA; CLARA, CARLOS AFONSO; et al. Copy Number Profiling of Brazilian Astrocytomas. G3-GENES, GENOMES, GENETICS, v. 6, n. 7, p. 1867-1878, JUL 1 2016. Web of Science Citations: 2. (13/25787-3, 12/19590-0, 11/08523-7, 12/08287-4)
BIDINOTTO, LUCAS TADEU; VEO, CARLOS A. R.; LOAIZA, EDGAR ALEMAN; SANTOS DE FRANCA, ALESSANDRA PAULINO; LORENZI, ADRIANA TARLA; REIS ROSA, LUCIANA ALBINA; DE OLIVEIRA, CRISTINA MENDES; LEVI, JOSE EDUARDO; SCAPULATEMPO-NETO, CRISTOVAM; LONGATTO-FILHO, ADHEMAR; et al. Low mutation percentage of KRAS and BRAF genes in Brazilian anal tumors. MOLECULAR MEDICINE REPORTS, v. 14, n. 4, p. 3791-3797, OCT 2016. Web of Science Citations: 1. (10/16795-4, 11/08523-7)
CAMPANELLA, NATHALIA C.; BERARDINELLI, GUSTAVO N.; SCAPULATEMPO-NETO, CRISTOVAM; VIANA, DANILO; PALMERO, EDENIR I.; PEREIRA, RUI; REIS, RUI M.. Optimization of a pentaplex panel for MSI analysis without control DNA in a Brazilian population: correlation with ancestry markers. European Journal of Human Genetics, v. 22, n. 7, p. 875-880, JUL 2014. Web of Science Citations: 14. (12/01732-2)
CAMPANELLA, NATHALIA C.; PENNA, VALTER; RIBEIRO, GUILHERME; ABRAHAO-MACHADO, LUCAS FARIA; SCAPULATEMPO-NETO, CRISTOVAM; REIS, RUI MANUEL. Absence of Microsatellite Instability In Soft Tissue Sarcomas. PATHOBIOLOGY, v. 82, n. 1, p. 36-42, 2015. Web of Science Citations: 5. (13/25787-3)
GRASSI, TONY F.; DA SILVA, GLENDA N.; BIDINOTTO, LUCAS T.; ROSSI, BRUNA F.; QUINALHA, MARILIA M.; KASS, LAURA; MUNOZ-DE-TORO, MONICA; BARBISAN, LUIS F.. Global gene expression and morphological alterations in the mammary gland after gestational exposure to bisphenol A, genistein and indole-3-carbinol in female Sprague-Dawley offspring. Toxicology and Applied Pharmacology, v. 303, p. 101-109, JUL 15 2016. Web of Science Citations: 1. (09/17894-9, 11/14655-3, 11/06219-9, 11/08523-7, 10/14110-4)
CAMPANELLA, NATHALIA C.; PENNA, VALTER; ABRAHAO-MACHADO, LUCAS FARIA; CRUVINEL-CARLONI, ADRIANA; RIBEIRO, GUILHERME; SOARES, PAULA; SCAPULATEMPO-NETO, CRISTOVAM; REIS, RUI M.. TERT promoter mutations in soft tissue sarcomas. International Journal of Biological Markers, v. 31, n. 1, p. E62-E67, JAN-MAR 2016. Web of Science Citations: 5. (13/25787-3)
CAMPANELLA, NATHALIA C.; PENNA, VALTER; ABRAHAO-MACHADO, LUCAS FARIA; CRUVINEL-CARLONI, ADRIANA; RIBEIRO, GUILHERME; SOARES, PAULA; SCAPULATEMPO-NETO, CRISTOVAM; REIS, RUI M.. TERT Promoter Mutations in Soft Tissue Sarcomas. International Journal of Biological Markers, v. 31, n. 1, p. 62-67, 2016. Web of Science Citations: 0. (13/25787-3)
BRUNHARA, BRUNO B.; BECKER, ALINE P.; NEDER, LUCIANO; GONCALVES, PAOLA G.; DE OLIVEIRA, CRISTIANE; CLARA, CARLOS A.; REIS, RUI M.; BIDINOTTO, LUCAS T.. Evaluation of the prognostic potential of EGFL7 in pilocytic astrocytomas. NEUROPATHOLOGY, NOV 2020. Web of Science Citations: 0. (16/23919-8, 12/19590-0, 17/09749-5, 16/21727-4)
MACKAY, ALAN; BURFORD, ANNA; CARVALHO, DIANA; IZQUIERDO, ELISA; FAZAL-SALOM, JANAT; TAYLOR, KATHRYN R.; BJERKE, LYNN; CLARKE, MATTHEW; VINCI, MARA; NANDHABALAN, MEERA; et al. Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma. CANCER CELL, v. 32, n. 4, p. 520+, OCT 9 2017. Web of Science Citations: 115. (11/08523-7, 12/08287-4)
BIDINOTTO, LUCAS TADEU; TORRIERI, RAUL; MACKAY, ALAN; ALMEIDA, GISELE CARAVINA; VIANA-PEREIRA, MARTA; CRUVINEL-CARLONI, ADRIANA; SPINA, MARIA LUISA; CAMPANELLA, NATHALIA CRISTINA; DE MENEZES, WEDER PEREIRA; CLARA, CARLOS AFONSO; et al. Copy Number Profiling of Brazilian Astrocytomas. G3-GENES, GENOMES, GENETICS, v. 6, n. 7, p. 1867-1878, JUL 1 2016. Web of Science Citations: 2. (12/19590-0, 11/08523-7, 12/08287-4, 13/25787-3)
BIDINOTTO, LUCAS TADEU; VEO, CARLOS A. R.; LOAIZA, EDGAR ALEMAN; SANTOS DE FRANCA, ALESSANDRA PAULINO; LORENZI, ADRIANA TARLA; REIS ROSA, LUCIANA ALBINA; DE OLIVEIRA, CRISTINA MENDES; LEVI, JOSE EDUARDO; SCAPULATEMPO-NETO, CRISTOVAM; LONGATTO-FILHO, ADHEMAR; et al. Low mutation percentage of KRAS and BRAF genes in Brazilian anal tumors. MOLECULAR MEDICINE REPORTS, v. 14, n. 4, p. 3791-3797, OCT 2016. Web of Science Citations: 1. (11/08523-7, 10/16795-4)
PINTO, FILIPE; COSTA, ANGELA M.; ANDRADE, RAQUEL P.; REIS, RUI MANUEL. Brachyury Is Associated with Glioma Differentiation and Response to Temozolomide. NEUROTHERAPEUTICS, v. 17, n. 4, SI, AUG 2020. Web of Science Citations: 0. (12/19590-0)
CAMPANELLA, NATHALIA C.; SCAPULATEMPO-NETO, CRISTOVAM; ABRAHAO-MACHADO, LUCAS FARIA; TORRES DE OLIVEIRA, ANTONIO TALVANE; BERARDINELLI, GUSTAVO N.; GUIMARAES, DENISE PEIXOTO; REIS, RUI M.. Lack of microsatellite instability in gastrointestinal stromal tumors. Oncology Letters, v. 14, n. 5, p. 5221-5228, NOV 2017. Web of Science Citations: 2. (13/25787-3)
ABRAHAO-MACHADO, LUCAS FARIA; ANTUNES, BRUNO; FILIPPI, RENEE ZON; VOLC, SAHLUA; BOLDRINI, ERICA; MENEZES, WEDER P.; REIS, RUI M.; DE CAMARGO, OLAVO PIRES. Loss of MTAP expression is a negative prognostic marker in Ewing sarcoma family of tumors. BIOMARKERS IN MEDICINE, v. 12, n. 1, p. 35-44, JAN 2018. Web of Science Citations: 0. (16/06833-2)
BECKER, ALINE PAIXAO; SCAPULATEMPO-NETO, CRISTOVAM; CARLONI, ADRIANA C.; PAULINO, ALESSANDRA; SHEREN, JAMIE; AISNER, DARA L.; MUSSELWHITE, EVELYN; CLARA, CARLOS; MACHADO, HELIO R.; OLIVEIRA, RICARDO S.; et al. KIAA1549: BRAF Gene Fusion and FGFR1 Hotspot Mutations Are Prognostic Factors in Pilocytic Astrocytomas. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, v. 74, n. 7, p. 743-754, JUL 2015. Web of Science Citations: 30. (12/19590-0)
BECKER, ALINE PAIXAO; SCAPULATEMPO-NETO, CRISTOVAM; MENEZES, WEDER P.; CLARA, CARLOS; MACHADO, HELIO R.; OLIVEIRA, RICARDO S.; NEDER, LUCIANO; REIS, RUI MANUEL. Expression of Methylthioadenosine Phosphorylase (MTAP) in Pilocytic Astrocytomas. PATHOBIOLOGY, v. 82, n. 2, p. 84-89, 2015. Web of Science Citations: 5. (12/19590-0)
VIANA-PEREIRA, MARTA; ALMEIDA, GISELE CARAVINA; STAVALE, JOAO NORBERTO; MALHEIRO, SUSANA; CLARA, CARLOS; LOBO, PATRICIA; PIMENTEL, JOSE; REIS, RUI MANUEL. Study of hTERT and Histone 3 Mutations in Medulloblastoma. PATHOBIOLOGY, v. 84, n. 2, p. 108-113, 2017. Web of Science Citations: 3. (12/19590-0)
DE MENEZES, WEDER PEREIRA; OLIVEIRA SILVA, VIVIANE ALINE; FARIA GOMES, IZABELA NATALIA; ROSA, MARCELA NUNES; CORCOLL SPINA, MARIA LUISA; CARLONI, ADRIANA CRUVINEL; VIEIRA ALVES, ANA LAURA; MELENDEZ, MATIAS; ALMEIDA, GISELE CARAVINA; DA SILVA, LUCIANE SUSSUCHI; et al. Loss of 5 `-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness. CELLS, v. 9, n. 2, FEB 2020. Web of Science Citations: 0. (16/18907-0, 17/22305-9, 16/06833-2)
VIANA-PEREIRA, MARTA; ALMEIDA, GISELE CARAVINA; STAVALE, JOAO NORBERTO; MALHEIRO, SUSANA; CLARA, CARLOS; LOBO, PATRICIA; PIMENTEL, JOSE; REIS, RUI MANUEL. Study of hTERT and Histone 3 Mutations in Medulloblastoma. PATHOBIOLOGY, v. 84, n. 2, p. 108-113, 2017. Web of Science Citations: 3. (12/19590-0)
DE MENEZES, WEDER PEREIRA; OLIVEIRA SILVA, VIVIANE ALINE; FARIA GOMES, IZABELA NATALIA; ROSA, MARCELA NUNES; CORCOLL SPINA, MARIA LUISA; CARLONI, ADRIANA CRUVINEL; VIEIRA ALVES, ANA LAURA; MELENDEZ, MATIAS; ALMEIDA, GISELE CARAVINA; DA SILVA, LUCIANE SUSSUCHI; et al. Loss of 5 `-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness. CELLS, v. 9, n. 2, FEB 2020. Web of Science Citations: 0. (16/18907-0, 17/22305-9, 16/06833-2)
VIEIRA ALVES, ANA LAURA; COSTA, ANGELA MARGARIDA; MARTINHO, OLGA; DA SILVA, VINICIUS DUVAL; JORDAN, PETER; OLIVEIRA SILVA, VIVIANE ALINE; REIS, RUI MANUEL. WNK2 Inhibits Autophagic Flux in Human Glioblastoma Cell Line. CELLS, v. 9, n. 2, FEB 2020. Web of Science Citations: 0. (16/18907-0)
CAMPANELLA, NATHALIA C.; SCAPULATEMPO-NETO, CRISTOVAM; ABRAHAO-MACHADO, LUCAS FARIA; TORRES DE OLIVEIRA, ANTONIO TALVANE; BERARDINELLI, GUSTAVO N.; GUIMARAES, DENISE PEIXOTO; REIS, RUI M.. Lack of microsatellite instability in gastrointestinal stromal tumors. Oncology Letters, v. 14, n. 5, p. 5221-5228, NOV 2017. Web of Science Citations: 2. (13/25787-3)
CRUVINEL-CARLONI, ADRIANA; SILVA-OLIVEIRA, RENATO; TORRIERI, RAUL; BIDINOTTO, LUCAS TADEU; BERARDINELLI, GUSTAVO NORIZ; OLIVEIRA-SILVA, VIVIANE ALINE; CLARA, CARLOS AFONSO; DE ALMEIDA, GISELE CARAVINA; MARTINHO, OLGA; SQUIRE, JEREMY ANDREW; et al. Molecular characterization of short-term primary cultures and comparison with corresponding tumor tissue of Brazilian glioblastoma patients. TRANSLATIONAL CANCER RESEARCH, v. 6, n. 2, p. 332+, APR 2017. Web of Science Citations: 4. (11/08523-7, 12/19590-0, 12/08287-4)
ABRAHAO-MACHADO, LUCAS FARIA; ANTUNES, BRUNO; FILIPPI, RENEE ZON; VOLC, SAHLUA; BOLDRINI, ERICA; MENEZES, WEDER P.; REIS, RUI M.; DE CAMARGO, OLAVO PIRES. Loss of MTAP expression is a negative prognostic marker in Ewing sarcoma family of tumors. BIOMARKERS IN MEDICINE, v. 12, n. 1, p. 35-44, JAN 2018. Web of Science Citations: 0. (16/06833-2)
EVANGELISTA, ADRIANE FEIJO; DE MENEZES, WEDER PEREIRA; BERARDINELLI, GUSTAVO NORIZ; DOS SANTOS, WELLINGTON; SCAPULATEMPO-NETO, CRISTOVAM; GUIMARAES, DENISE PEIXOTO; CALIN, GEORGE A.; REIS, RUI MANUEL. Pyknon-Containing Transcripts Are Downregulated in Colorectal Cancer Tumors, and Loss of PYK44 Is Associated With Worse Patient Outcome. FRONTIERS IN GENETICS, v. 11, NOV 12 2020. Web of Science Citations: 0.
CAMPANELLA, NATHALIA C.; SILVA, EDUARDO CAETANO; DIX, GUSTAVO; VAZQUEZ, FABIANA DE LIMA; DE PAULA, FLAVIA ESCREMIM; BERARDINELLI, GUSTAVO N.; BALANCIN, MARCELO; CHAMMAS, ROGER; MENDOZA LOPEZ, V, ROSSANA; SILVEIRA, HENRIQUE CESAR S.; et al. Mutational Profiling of Driver Tumor Suppressor and Oncogenic Genes in Brazilian Malignant Pleural Mesotheliomas. PATHOBIOLOGY, v. 87, n. 3, p. 208-215, JUN 2020. Web of Science Citations: 0. (16/03634-9)
PINTO, FILIPE; COSTA, ANGELA M.; ANDRADE, RAQUEL P.; REIS, RUI MANUEL. Brachyury Is Associated with Glioma Differentiation and Response to Temozolomide. NEUROTHERAPEUTICS, v. 17, n. 4, SI, AUG 2020. Web of Science Citations: 0. (12/19590-0)