CV Lattes
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Fundação Pio XII (FP). Hospital do Câncer de Barretos (Institutional affiliation for the last research proposal) Birthplace: Portugal
Scientific Director of the Teaching and Research Institute (IEP); Coordinator of the Molecular Oncology Research Center (CPOM); and Scientific Director of the Molecular Diagnostic Laboratory at the Barretos Cancer Hospital, Barretos, SP. Brazil. Invited Associate Professor at the University of Minho School of Medicine (Braga, Portugal). Extraordinary Professor, Pan African Cancer Research Institute, University of Pretoria, South Africa. Graduation in biology, University of Porto (Portuga) l; doctorate in neuro-oncology, IARC (Lyon, France); postdoctoral fellow in cancer genomics, Free University Medical Center (Amsterdam, Netherlands) and IPATIMUP (Porto, Portugal). (Source: Lattes Curriculum)
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SUMMARY ANNUAL PLAN 1 - AUDIOVISUAL CONTENT PRODUCTION STUDIO. The Teaching and Research Institute (IEP) of Hospital de Amor, seeks to improve the work carried out by the Distance Education sector (EaD), which started its activities in 2014, through the coordination of the Cancer Education Center. Since then, the sector has provided online courses and training in Health Education with a f…
Gliobastomas are the most frequent and malignant brain neoplasia among the central nervous system tumors. These are incurable neoplasias, with mean survival of 13 months, and less than 2% of the patients reach 5 years post treatment. The low success in the treatment of these tumors are, in part, due to the little understanding of their molecular bases. Moreover, several in vitro studies a…
Glioblastoma (GBM) is one of the most common neoplasia of the central nervous system, is characterized as a highly aggressive and invasive tumor, is related to high mortality rates and a poor prognosis. Currently, the standard treatment of this disease consists of surgical removal of the tumor, followed by chemotherapy associated with the use of temozolomide (TMZ), a DNA alkylating agent.…
Lung cancer is responsible for 1 in 5 cancer deaths worldwide. The high number of deaths is due to the late diagnosis and the low effectiveness of therapeutic strategies. The pulmonary neoplasia can be divided into non-small cells lung cancer (NSCLC), corresponding to 85% of cases, and small cell cancer. Histologically, it can be divided into adenocarcinoma, squamous cell carcinoma, and s…
Cancer is responsible for a significant and growing number of patients worldwide, and represents the second leading cause of death in many countries. In the search for new therapies, research with natural products has emerged as an alternative and successful source in the development of potential drugs. The species Euphorbia tirucalli, popularly known as ''aveloz'' is used in folk medicin…
The Epidermal Growth Factor Receptor (EGFR) is an important protein which activation leads to the signaling of intracellular pathways that act directly on cell proliferation, migration and survival. Cetuximab (CTX), is an anti-EGFR monoclonal antibody that has been approved for the treatment of Head and Neck Squamous Cell Carcinoma (HNSCC) patients and metastatic Colorectal Cancer (mCRC).…
Glioblastoma (GBM) is a highly aggressive and invasive tumor that confers high mortality rates and low survival. The standard treatment consists of surgical resection of the tumor, accompanied by radiotherapy and chemotherapy associated with the use of temozolomide (TMZ), a DNA alkylating agent that, administered to the patient, promotes a slight increase in survival. However, GBM present…
Gliomas are malignant brain tumors and are the most frequent among the central nervous system tumors. The majority of gliomas are untreatable, and when treated with the standard protocol, the mean survival is of approximately 14 months. The irrelevant success in the treatment of these tumors is not only due to the low understanding of their molecular bases, but also due to the use of a st…
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The gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract whose prognosis of the patients is based on criteria including tumor size, mitotic index and localization. Despite of this classification, GIST progression is often inaccurate. The aim of this study is to elucidate the biological role and therapeutic potential biomarker TERT in…
Gliomas are the most frequent and malignant tumors within the Central System Nervous (CNS) tumors. They are an incurable neoplasia, with a survival average of approximately 13 months, and less than 2% of the patients survive 5 years after the treatment. The low success in the treatment of these tumors is, in part, due to the low understanding of their molecular bases. The present project …
| 2 / 2 | Ongoing research grants |
| 6 / 2 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 12 / 11 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 25 / 20 | All research grants and scholarships |
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