- Research Grants
Has experience in Genetics, focusing on Human and Medical Genetics (Source: Lattes Curriculum)
Persistent infection by Helicobacter pylori causes chronic inflammation and consequent development of gastric lesions that may progress to intestinal type gastric cancer. The inflammatory response triggered by this pathogen is characterized by the induction of inflammatory cytokines expression, highlighting the tumor necrosis factor (TNF)-± as presenting tumor promoting function. TNF-± ...
Chronic inflammation provides a favorable microenvironment for neoplastic transformation, often due to persistent infection by pathogens. In this model, fits in gastric cancer as a result of infection by the bacterium Helicobacter pylori. Persistent infection by this bacterium promotes chronic inflammation, the main etiological factor for stomach cancer progression from atrophic gastrit...
Gastric cancer remains the second leading cause of cancer-related death worldwide, despite the reduction in its incidence. The main risk factors consist of premalignant lesions of the gastric mucosa, such as chronic gastritis, metaplasia and dysplasia, often initiated by chronic inflammation caused by the bacterium Helicobacter pylori. Gastric ulcer, a chronic injury of the gastric muco...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|
(References retrieved automatically from State of São Paulo Research Institutions)
FREIRE, Ana Flávia Teixeira Rossi. Efeito do tratamento da H. pylori na expressão de citocinas e microRNAs associados ao processo inflamatório. 105 f. Dissertação (Mestrado) - Universidade Estadual Paulista "Júlio de Mesquita Filho" Instituto de Biociências, Letras e Ciências Exatas. (13/03625-1)
FREIRE, Ana Flávia Teixeira Rossi. Avaliação de mediadores da via de sinalização do fator de necrose tumoral alfa e de microRNAs em câncer gástrico e efeito do silenciamento de seus receptores. 123 f. Tese (Doutorado) - Universidade Estadual Paulista "Júlio de Mesquita Filho" Instituto de Biociências, Letras e Ciências Exatas. (15/23392-7)