- Research Grants
graduation at Farmácia-Bioquímica from Universidade de São Paulo (2010) and master's at Pharmacy from Universidade de São Paulo (2013). Has experience in Pharmacy, acting on the following subjects: cetuximab, terapia fotodinâmica, liquid crystal, clorina and photodynamic therapy. (Source: Lattes Curriculum)
Topical treatment has been studied as a promising alternative for skin cancer therapy. Our research group has evaluated ways to increase the skin penetration of chemotherapeutic drugs so that they are able to reach deeper layers of the skin. It is known that techniques such as iontophoresis and ultrasound promote the skin penetration of both small and macromolecules. However, both techn...
Among skin cancers, the squamous cell carcinoma (SCC) helds the second position in frequency and is biologically more aggressive than the basocelular skin cancer. The topical chemotherapy of these tumors is a promising strategy for the reduction of the side effects associated to this kind of therapy. The cell pathway interruption using monoclonal antibodies, such as Cetuximab, is also a...
The process of RNA interference refers to the silencing of genes post transcriptional sequence-specific in animals and plants that can be promoted by dsRNA that is homologous to the sequence of the silenced gene. This type of therapy has the advantages of specificity for the targets chosen, the possibility of treating a wide range of genetic diseases, besides being very potent and effec...
Among skin cancers, the squamous cell carcinoma (SCC) holds the second position in frequency and is biologically more aggressive than the basocelular skin cancer. SCC over-expresses the epidermal growth factor receptor (EGFR), which is responsible for communicating extracellular signals to the nucleus and is commonly associated with bad prognosis. The interruption of the signaling cell ...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|
(References retrieved automatically from State of São Paulo Research Institutions)
PETRILLI, Raquel. Aplicação tópica de lipossomas contendo cetuximabe: efeito do uso de métodos físicos de penetração cutânea no carcinoma celular escamoso de pele. Tese (Doutorado) - Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto. (12/23764-3)
PETRILLI, Raquel. Nanopartículas de fase líquido cristalina hexagonal funcionalizadas com peptídeos de transdução para veiculação de siRNA na terapia de doenças tópicas. Dissertação (Mestrado) - Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto. (11/02630-6)