CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduation at Ciências Biológicas from Universidade São Judas Tadeu (1994), master's at Pharmacology from Universidade de São Paulo (2000) and doctorate at Pharmacology from Universidade de São Paulo (2004). Has experience in Pharmacology, acting on the following subjects: hiperalgesia, fosfolipases a2, veneno de bothrops jararaca, alodynia and bothropa asper venom. (Source: Lattes Curriculum)
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The technique of photobiostimulation, use of light as therapy, is a non-invasive method that has been shown both in basic and in clinical research to be effective in reducing pain sensitivity and consequently improving the quality of life of patients with neuropathic pain. The present study aims to examine the effects of low level laser (LLLT) on pain sensitivity and sciatic nerve repair …
Trigeminal neuralgia (NT) is a common cause of facial pain. It has a significant impact on quality of life and socioeconomic functioning of the patient. The International Association for the Study of Pain (IASP) defines NT as a painful unilateral disorder characterized by episodes of pain like an electric shock that begin and end by abrupt way. Among several models of neuropathy using ner…
(Only some records are available in English at this moment)
Primary cell damage from Schwann cells in hyperglycemia is largely neglected in terms of Diabetic Peripheral Neuropathy. This situation results from the historical attention given to micro and macrovascular diseases from Diabetes. In contrast, the mechanisms by which low level laser therapy generates its promising effects is still the field of extensive research. It is proposed here, thro…
About 425 million people around the world are Diabetic, and approximately 60 % develop Peripheral Diabetic Neuropathy (PDN), which is characterized by moderate to severe pain involving the upper and lower limbs. The painful symptoms appear after metabolic alterations in the Dorsal Root Ganglia (DRG) afferent neurons and in the Schwann cells from the peripheral nerves, causing it progressi…
Parkinson's disease (PD) is the second most common neurodegenerative disease among elderly people, causing a large socioeconomic impact with increasing life expectancy of worldwide. In addition to motor symptoms, there is a high prevalence of pain symptoms which can be responsible for worsening patient's quality of life. Physical exercise, in turn, has already been described for its benef…
Musculoskeletal pain is a high occurrence in the world population and is a public health problem. Among musculoskeletal pain, there is the subgroup of muscular pain, which affects a large part of society. For this reason, our project focuses on the study of muscular pain in different periods of development, before its installation, in acute and chronic form. The overall objective of this …
(Only some records are available in English at this moment)
Major depressive disorder (MDD) is a severe disorder affecting 21 million Americans (~10 %) per year and is the third leading cause of global disability. There is evidence that the prevalence of MDD is moderately increased in prediabetic patients and in undiagnosed diabetic patients, and markedly increased in the previously diagnosed diabetic patients compared to normal glucose metabolism…
Chronic pain disorders are a public health problem due to its high prevalence, high economic cost, and negative impact on patient quality of life. Animal models of chronic inflammatory and neuropathic pain represent an unprecedented opportunity to identify novel mechanisms underlying both their production and their effective management. Recent development of genetic tools for high spatial…
For a long time, much attention has been given to the detrimental effects of diabetes in the peripheral nervous system. Chronic hyperglycemia has also deleterious effects in the central nervous system (CNS) in the long term and when left untreated. Microglia, the resident macrophages in the CNS play a key role in maintaining homeostasis and in driving a variety of CNS diseases, including …
Parkinson's disease (PD) is the second most common neurodegenerative disease among elderly people, causing a large socioeconomic impact with increasing life expectancy of worldwide. In addition to motor symptoms, there is a high prevalence of pain symptoms which can be responsible for worsening patient's quality of life. Physical exercise, in turn, has already been described for its benef…
Vitamin D (VD) exerts a fundamental role in several biological processes. Its effects on bone and calcium metabolism are vastly known. Recently, some findings linked the VD to neuroinflammatory processes and, more recently, to pain and nociception. Those findings suggest that VD may play a pivotal role on intracellular mechanisms, influencing intracellular calcium concentrations. Calcium …
Inflammations are the cause of several diseases found in the population and are involved in various psychiatric disorders. When an inflammatory process is started, immune cells and immunoactive agents are released in the tissue. Astrocytes and microglia are two different types of glial cells that are activated in the central and peripheral nervous system and play important roles in the de…
(Only some records are available in English at this moment)
| 5 / 4 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 29 / 21 | Completed scholarships in Brazil |
| 3 / 3 | Ongoing scholarships abroad |
| 7 / 6 | Completed scholarships abroad |
| 45 / 35 | All research grants and scholarships |
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