Marucia Chacur
CV Lattes
ResearcherID
ORCID
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduation at Ciências Biológicas from Universidade São Judas Tadeu (1994), master's at Pharmacology from Universidade de São Paulo (2000) and doctorate at Pharmacology from Universidade de São Paulo (2004). Has experience in Pharmacology, acting on the following subjects: hiperalgesia, fosfolipases a2, veneno de bothrops jararaca, alodynia and bothropa asper venom. (Source: Lattes Curriculum)
- Effect of photobiostimulation on different peripheral neuropathies in rats, AP.R
Abstract
The technique of photobiostimulation, use of light as therapy, is a non-invasive method that has been shown both in basic and in clinical research to be effective in reducing pain sensitivity and consequently improving the quality of life of patients with neuropathic pain. The present study aims to examine the effects of low level laser (LLLT) on pain sensitivity and sciatic nerve repai...
- Photodynamic therapy in trigeminal neuralgia, AP.R
Abstract
Trigeminal neuralgia (NT) is a common cause of facial pain. It has a significant impact on quality of life and socioeconomic functioning of the patient. The International Association for the Study of Pain (IASP) defines NT as a painful unilateral disorder characterized by episodes of pain like an electric shock that begin and end by abrupt way. Among several models of neuropathy using n...
- 7th world Congress world institute of pain, AR.EXT
(Only some records are available in English at this moment)
- Effect of physical exercise on induced nociception in the Parkinson's Disease model in rats, BP.MS
Abstract
Parkinson's disease (PD) is the second most common neurodegenerative disease among elderly people, causing a large socioeconomic impact with increasing life expectancy of worldwide. In addition to motor symptoms, there is a high prevalence of pain symptoms which can be responsible for worsening patient's quality of life. Physical exercise, in turn, has already been described for its ben...
- Study of the effects of the photobiostimulation on the Schwann cell mitochondrial metabolism in Type 1 Diabetes Mellitus, BP.DR
Abstract
Primary cell damage from Schwann cells in hyperglycemia is largely neglected in terms of Diabetic Peripheral Neuropathy. This situation results from the historical attention given to micro and macrovascular diseases from Diabetes. In contrast, the mechanisms by which low level laser therapy generates its promising effects is still the field of extensive research. It is proposed here, th...
- Evaluation of photobiostimulation in myositis, BP.IC
Abstract
Musculoskeletal pain is a high occurrence in the world population and is a public health problem. Among musculoskeletal pain, there is the subgroup of muscular pain, which affects a large part of society. For this reason, our project focuses on the study of muscular pain in different periods of development, before its installation, in acute and chronic form. The overall objective of thi...
- Analysis of postural changes in patients with low back pain treated with neural mobilization, BP.IC
Abstract
Low back pain is the most frequent clinical condition that affects a worldwide population. This type of disorder causes a major impact socio-economically, psychologically and quality of life, with inconclusive diagnosis and treatments and low efficacy. The neuropathic pain leads the individual to adopt antalgic posture unconsciously, that could causes changes in the musculoskeletal arra...
(Only some records are available in English at this moment)
- Role of opioids, cannabinoids, dopamine and neuroinflammation systems on pain threshold modulated by physical exercise in a rat Parkinson Disease model using a radioactive labeled substances, BE.EP.MS
Abstract
Parkinson's disease (PD) is the second most common neurodegenerative disease among elderly people, causing a large socioeconomic impact with increasing life expectancy of worldwide. In addition to motor symptoms, there is a high prevalence of pain symptoms which can be responsible for worsening patient's quality of life. Physical exercise, in turn, has already been described for its ben...
- Effects of vitamin D on intracellular calcium of primary neuronal cultures, BE.EP.IC
Abstract
Vitamin D (VD) exerts a fundamental role in several biological processes. Its effects on bone and calcium metabolism are vastly known. Recently, some findings linked the VD to neuroinflammatory processes and, more recently, to pain and nociception. Those findings suggest that VD may play a pivotal role on intracellular mechanisms, influencing intracellular calcium concentrations. Calciu...
- Involvement of microglia in circadian system, BE.EP.IC
Abstract
Inflammations are the cause of several diseases found in the population and are involved in various psychiatric disorders. When an inflammatory process is started, immune cells and immunoactive agents are released in the tissue. Astrocytes and microglia are two different types of glial cells that are activated in the central and peripheral nervous system and play important roles in the ...
(Only some records are available in English at this moment)
| 5 / 4 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 28 / 20 | Completed scholarships in Brazil |
| 7 / 6 | Completed scholarships abroad |
| 41 / 31 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 15 |
| Citations | 83 |
| Cit./Article | 5.5 |
| Data from Web of Science | |
MARTINS, DANIEL DE OLIVEIRA; DOS SANTOS, FABIO MARTINEZ; DE OLIVEIRA, MARA EVANY; DE BRITTO, LUIZ R. G.; DIAS LEMOS, JOSE BENEDITO; CHACUR, MARUCIA. Laser Therapy and Pain-Related Behavior after Injury of the Inferior Alveolar Nerve: Possible Involvement of Neurotrophins. JOURNAL OF NEUROTRAUMA, v. 30, n. 6, p. 480-486, MAR 2013. Web of Science Citations: 5. (11/22268-0, 10/20026-6)
RODRIGUES, ALEX DE FREITAS; MARTINS, DANIEL DE OLIVEIRA; CHACUR, MARUCIA; LUZ, JOAO GUALBERTO C.. The effectiveness of photobiomodulation in the management of temporomandibular pain sensitivity in rats: behavioral and neurochemical effects. Lasers in Medical Science, v. 35, n. 2, p. 447-453, MAR 2020. Web of Science Citations: 0. (17/05218-5)
BINDA, K. H.; REAL, C. C.; FERREIRA, A. F. F.; BRITTO, L. R.; CHACUR, M.. Antinociceptive effects of treadmill exercise in a rat model of Parkinson's disease: The role of cannabinoid and opioid receptors. Brain Research, v. 1727, JAN 15 2020. Web of Science Citations: 0. (17/05218-5, 17/26821-1)
MARTINS, DANIEL OLIVEIRA; DOS SANTOS, FABIO MARTINEZ; CIENA, ADRIANO POLICAN; WATANABE, II-SEI; DE BRITTO, LUIZ ROBERTO G.; DIAS LEMOS, JOSE BENEDITO; CHACUR, MARUCIA. Neuropeptide expression and morphometric differences in crushed alveolar inferior nerve of rats: Effects of photobiomodulation. Lasers in Medical Science, v. 32, n. 4, p. 833-840, MAY 2017. Web of Science Citations: 4. (14/24533-0, 10/20026-6, 12/05840-4)
HUBBARD, CATHERINE S.; KARPOWICZ, JANE M.; FURMAN, ANDREW J.; DA SILVA, JOYCE TEIXEIRA; SEMINOWICZ, DAVID A.; TRAUB, RICHARD J.. Estrogen-dependent visceral hypersensitivity following stress in rats: An fMRI study. MOLECULAR PAIN, v. 12, JUN 17 2016. Web of Science Citations: 4. (14/20983-1)
ROSA, A. S.; FREITAS, M. F.; ROCHA, I. R. C.; CHACUR, M.. Gabapentin decreases microglial cells and reverses bilateral hyperalgesia and allodynia in rats with chronic myositis. European Journal of Pharmacology, v. 799, p. 111-117, MAR 15 2017. Web of Science Citations: 5. (14/24533-0)
SANTOS, FABIO MARTINEZ; GRECCO, LEANDRO HENRIQUE; PEREIRA, MARCELO GOMES; OLIVEIRA, MARA EVANY; ROCHA, PRISCILA ABREU; SILVA, JOYCE TEIXEIRA; MARTINS, DANIEL OLIVEIRA; MIYABARA, ELEN HARUKA; CHACUR, MARUCIA. The neural mobilization technique modulates the expression of endogenous opioids in the periaqueductal gray and improves muscle strength and mobility in rats with neuropathic pain. Behavioral and Brain Functions, v. 10, MAY 13 2014. Web of Science Citations: 10. (12/24408-6, 10/20026-6, 12/05840-4)
CHACUR‚ M.; PICOLO‚ G.; TEIXEIRA‚ CFP; CURY‚ Y.. Bradykinin is involved in hyperalgesia induced by Bothrops jararaca venom. Toxicon, v. 40, n. 7, p. 1047-1051, 2002.
CHACUR‚ M.; GUTIÉRREZ‚ J. M.; MILLIGAN‚ E. D.; WIESELER-FRANK‚ J.; BRITTO‚ L. R. G.; MAIER‚ S. F.; WATKINS‚ L. R.; CURY‚ Y.. Snake venom components enhance pain upon subcutaneous injection: an initial examination of spinal cord mediators. Pain, v. 111, n. 1-2, p. 65-76, Sept. 2004.
OLIVEIRA, M. E.; SANTOS, F. M.; BONIFACIO, R. P.; FREITAS, M. F.; MARTINS, D. O.; CHACUR, M.. Low level laser therapy alters satellite glial cell expression and reverses nociceptive behavior in rats with neuropathic pain. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, v. 16, n. 4, p. 547-554, APR 1 2017. Web of Science Citations: 6. (10/20026-6, 12/05840-4, 13/01274-7)
TEIXEIRA, C. F. P.; LANDUCCI, E. C. T.; ANTUNES, E.; CHACUR, M.; CURY, Y.. Inflammatory effects of snake venom myotoxic phospholipases A(2). Toxicon, v. 42, n. 8, p. 947-962, Dec. 2003.
CHACUR‚ M.; PICOLO‚ G.; GUTIÉRREZ‚ JM; TEIXEIRA‚ CFP; CURY‚ Y.. Pharmacological modulation of hyperalgesia induced by Bothrops asper (terciopelo) snake venom. Toxicon, v. 39, n. 8, p. 1173-1181, 2001.
CHACUR, MARUCIA; LAMBERTZ, DANIELA; HOHEISEL, ULRICH; MENSE, SIEGFRIED. Role of spinal microglia in myositis-induced central sensitisation: An immunohistochemical and behavioural study in rats. EUROPEAN JOURNAL OF PAIN, v. 13, n. 9, p. 915-923, OCT 2009. Web of Science Citations: 27.
CORREIA ROCHA, IGOR RAFAEL; CIENA, ADRIANO POLICAN; ROSA, ALYNE SANTANA; MARTINS, DANIEL OLIVEIRA; CHACUR, MARUCIA. Photobiostimulation reverses allodynia and peripheral nerve damage in streptozotocin-induced type 1 diabetes. Lasers in Medical Science, v. 32, n. 3, p. 495-501, APR 2017. Web of Science Citations: 1. (14/24533-0)
G. PICOLO; M. CHACUR; J.M. GUTIÉRREZ; C.F.P. TEIXEIRA; Y. CURY. Evaluation of antivenoms in the neutralization of hyperalgesia and edema induced by Bothrops jararaca and Bothrops asper snake venoms. Brazilian Journal of Medical and Biological Research, v. 35, n. 10, p. 1221-1228, Out. 2002.
DA SILVA, JOYCE TEIXEIRA; DOS SANTOS, FABIO MARTINEZ; GIARDINI, ALINE CAROLINE; MARTINS, DANIEL DE OLIVEIRA; DE OLIVEIRA, MARA EVANY; CIENA, ADRIANO POLICAN; GUTIERREZ, VANESSA PACCIARI; WATANABE, II-SEI; DE BRITTO, LUIZ ROBERTO G.; CHACUR, MARUCIA. Neural mobilization promotes nerve regeneration by nerve growth factor and myelin protein zero increased after sciatic nerve injury. GROWTH FACTORS, v. 33, n. 1, p. 8-13, FEB 2015. Web of Science Citations: 14. (11/22268-0)
DA SILVA, JOYCE T.; EVANGELISTA, BIANCA G.; VENEGA, RAFAEL A. G.; SEMINOWICZ, DAVID A.; CHACUR, MARUCIA. Anti-NGF treatment can reduce chronic neuropathic pain by changing peripheral mediators and brain activity in rats. Behavioural Pharmacology, v. 30, n. 1, p. 79-88, FEB 2019. Web of Science Citations: 0. (12/24408-6)
GIARDINI, ALINE CAROLINA; DOS SANTOS, FABIO MARTINEZ; DA SILVA, JOYCE TEIXEIRA; DE OLIVEIRA, MARA EVANY; MARTINS, DANIEL OLIVEIRA; CHACUR, MARUCIA. Neural Mobilization Treatment Decreases Glial Cells and Brain-Derived Neurotrophic Factor Expression in the Central Nervous System in Rats with Neuropathic Pain Induced by CCI in Rats. PAIN RESEARCH & MANAGEMENT, 2017. Web of Science Citations: 3. (12/24408-6, 11/22268-0, 10/20026-6, 14/24533-0, 12/05840-4)
DA SILVA, J. T.; EVANGELISTA, B. G.; VENEGA, R. A. G.; OLIVEIRA, M. E.; CHACUR, M.. EARLY AND LATE BEHAVIORAL CHANGES IN SCIATIC NERVE INJURY MAY BE MODULATED BY NERVE GROWTH FACTOR AND SUBSTANCE P IN RATS: A CHRONIC CONSTRICTION INJURY LONG-TERM EVALUATION. JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS, v. 31, n. 2, p. 309-319, APR-JUN 2017. Web of Science Citations: 4. (12/24408-6, 14/24533-0, 16/14675-8)
HOHEISEL, ULRICH; CHACUR, MARUCIA; TREEDE, ROLF-DETLEF; MENSE, SIEGFRIED. Action potentials and subthreshold potentials of dorsal horn neurons in a rat model of myositis: a study employing intracellular recordings in vivo. Journal of Neurophysiology, v. 122, n. 2, p. 632-643, AUG 2019. Web of Science Citations: 0.
(References retrieved automatically from State of São Paulo Research Institutions)
MARTINS, Daniel de Oliveira. Uso do laser de baixa intensidade e os mecanismos celulares e moleculares no processo de reparação no sistema nervoso periférico.. Tese (Doutorado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (10/20026-6)
CHACUR, Marucia. Efeito nociceptivo induzido por fosfolipases A2 (FLA2 variantes Lys49 e Asp49) isoladas do veneno de serpentes Bothrops asper: caracterização dos mecanismos centrais e determinantes moleculares. 195 f. Tese (Doutorado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (00/12303-8)
ROSA, Alyne Santana. Avaliação do efeito da gabapentina em modelo de dor muscular crônica em ratos.. Dissertação (Mestrado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (15/26038-0)
SANTOS, Fabio Martinez dos. Mobilização neural: avaliação molecular e comportamental em ratos Wistar após indução de dor neuropática.. Tese (Doutorado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (12/05840-4)
SILVA, Joyce Teixeira da. Ressonância magnética e ativação neuronal supraespinal em modelo de dor neuropática crônica em ratos.. Tese (Doutorado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (12/24408-6)
SILVA, Mara Evany de Oliveira. Avaliação da radiação LASER AsGa 904nm sobre o processo álgico no modelo de dor neuropática em ratos.. Dissertação (Mestrado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (13/01274-7)
ROCHA, Igor Rafael Correia. Efeito da fotobioestimulação na neuropatia periférica de ratos com diabetes mellitus tipo 1 induzido por estreptozotocina.. Dissertação (Mestrado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (16/00038-6)
FREITAS, Milena Fernandes de. Mecanismos centrais da dor músculo-esquelética induzida por carregenina em ratos.. Dissertação (Mestrado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (09/12244-6)