CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Biological Sciences from Federal University of São Carlos (UFSCar), master and doctorate degree in Cell and Molecular Biology from Medicine School of Ribeirão Preto - University of São Paulo (FMRP-USP). With experience in cell and molecular biology, microbiology and innate immunity. Works in projects involvingIt infectious diseases, pathogen-host interaction and activation of inflammatory pathways. (Source: Lattes Curriculum)
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Recently, it has been discovered that Ninj1 plays a crucial role in plasma membrane rupture during various types of programmed cell death, including apoptosis, pyroptosis, and necroptosis. This finding opens new perspectives for better understanding the mechanisms involved in the regulation of cell death, especially in the context of neutrophils, where such mechanisms are still poorly und…
Bacteria of the genus Legionella are intracellular, Gram-negative organisms that cause a severe form of pneumonia known as Legionnaires' Disease. Among the best-known species, we have Legionella pneumophila, well described in the literature, and Legionella longbeachae, still little studied, but responsible for most outbreaks of this disease. The transmission of these pathogens occurs thro…
Legionella pneumophila is a facultative intracellular bacterium responsible for causing atypical pneumonia known as "legionnaires' disease". Studies with genetically altered mice showed that innate immune receptors present in the cytoplasm of infected macrophages, such NAIP5 and NLRC 4, participate in the control infection by a process dependent on caspase-1. Data from literature have dem…
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