bachelor's at Ciências Biológicas from Universidade Estadual Paulista Júlio de Mesquita Filho, UNESP, SJ Rio Preto (1990), master's at Ciências Biológicas from Universidade Estadual Paulista Júlio de Mesquita Filho, UNESP, SJ Rio Preto (1993) and doctorate at Ciências Biológicas from Universidade Estadual Paulista Júlio de Mesquita Filho, UNESP, SJ Rio Preto (1998). Has experience in Genetics, focusing on Human and Medical Genetics, acting on the following subjects: Down syndrome, head and neck cancer, poimorphisms, molecualr biology and neurofibromatosis. (Source: Lattes Curriculum)
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The intrinsically deficient immune system in Down syndrome (DS) may contribute to the increased susceptibility to infections related to the main causes of hospitalization and death of these individuals and also seems to favor neurodegenerative processes like Alzheimer's Disease. Chromosome 21 trisomy can cause global changes in gene expression, including those not located on chromosome 21…
The phenotype of Down syndrome (DS), more frequent human chromosomal disorder, is complex and variable among individuals, and may include multiple dysmorphic features, immunologic abnormalities, congenital heart defects, learning disabilities, neurological disorders, among others. Studies show that some genes involved in the immune system have altered expression in individuals with DS, ho…
Inconclusive results of the association between genetic polymorphisms involved in folate metabolism and maternal risk for Down syndrome (DS) have been reported. Therefore, this meta-analysis was conducted. We searched electronic databases through May, 2014 for eligible studies. Pooled odds ratios with 95% confidence intervals were used to assess the strength of the association, which was …
(Only some records are available in English at this moment)
The latest catalog of gene annotation and microRNAs (miRNAs), non-coding RNAs molecules involved in post-transcriptional gene regulation of chromosome 21, includes more than 223 coding genes and 30 miRNAs (HGNC, 2019). The contribution of these miRNAs to the Down syndrome (DS) phenotype is poorly investigated, but there is evidence some change in their expression could be related to manif…
The intrinsically deficient immune system in Down's Syndrome (SD) possibly contributes to the increased susceptibility of infections, which are related to the main causes of hospitalization and death of these individuals and also seems to be involved in neurodegenerative processes such as the early manifestation of Alzheimer's disease. Chromosome 21 trisomy can cause global changes in gen…
(Only some records are available in English at this moment)
| 17 / 9 | Completed research grants |
| 16 / 8 | Completed scholarships in Brazil |
| 33 / 17 | All research grants and scholarships |
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CV Lattes
ORCID