Abstract
Actinic keratosis (AK) is a preneoplastic skin lesion caused mainly by solar radiation on chronic photo exposed areas. It is characterized by the atypical proliferation of the skin's keratinocyte and has a significant risk of progression to squamous cell carcinoma (SCC). Nowadays it is known that about 60% of SCCs are originated from actinic keratosis. Chronically photo exposed skin prese…