CV Lattes
ResearcherID
ORCID
Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas (FCF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Biomedical Sciences from the Federal University of São Paulo (1993), master's degree in Microbiology and Immunology from the Federal University of São Paulo (1996) and Ph.D. in Microbiology and Immunology from the Federal University of São Paulo (1999). Postdoctoral fellow at the Washington University School of Medicine-USA (1999). He is currently an associate professor at the Faculty of Pharmaceutical Sciences - University of São Paulo. Editor of journals: Journal of Fungi, Brazilian Journal of Microbiology and Frontiers in Microbiology. He has published 88 scientific papers with h-index = 25 and has a licensed patent. He participates in several collegiate bodies at FCF-USP. He coordinated two FAPESP thematic projects, supervised 17 master's dissertations, 15 doctoral theses and supervised 8 post-docs. He was deputy coordinator (2012-2016) and coordinator (2016-2020) of the Graduate course in Pharmacy: Pathophysiology and Toxicology at FCF-USP, grade 7 CAPES, he was deputy head of the Department of Clinical and Toxicological Analysis at FCF-USP (2019-2021). He coordinates projects in the area of immune response against pathogenic fungi. (Source: Lattes Curriculum)
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Flow cytometry is a technology that has increasingly stood out in research and is responsible for several advances in science. Its application is not limited to a single area of knowledge, and can be used in the areas of immunology, hematology, genetics, cell biology, microbiology, parasitology, oceanography, in studies of new drugs and stem cell therapies, among many others. Its ability …
Chromoblastomycosis and sporotrichosis are the two main implantation mycoses that are now recognized as neglected tropical fungal diseases. Its laboratory diagnosis is based mainly on direct microscopy, histopathology and identification of the fungus by culture. Subcutaneous or implantation mycoses, such as sporotrichosis and chromoblastomycosis, result from the inoculation of the pathoge…
Chromoblastomycosis is a chronic and progressive subcutaneous mycosis caused mainly by the fungus Fonsecae pedrosoi. During the infections, exudatives lesions and granuloma (composed mainly by macrophages and neutrophils) are often observed in skin biopsies. Studies from the 90s suggested that conidia could survive inside macrophages. After stimulation with IFN-³, those macrophages would …
The present proposal of USP Visiting Researcher, for Dr. Leila Lopes Bezerra, coordinator of INCT Infecções Emergún Emergentes, approved in 2016, which involves two USP faculty / researchers who support this proposal, aims to develop, at least in part, the Projects of the nuclei Sporotrichosis and Paracoccidioidomycosis of this INCT. It should be noted that fungal infections, the focus of…
(Only some records are available in English at this moment)
The proposed postdoctoral project aims to investigate the immune response to sporotrichosis, a deep mycosis with increasing incidence and clinical relevance, particularly in Brazil. The focus of the study is the development and immunological evaluation of the recombinant GP70 protein, a vaccine candidate derived from the S. brasiliensis strain. The research will use C57BL/6J mice, includi…
Since 1998, the incidence of sporotrichosis in our country has grown exponentially, with alarming numbers. Human cases of the disease linked to zoonotic transmission by felines have been described in Rio de Janeiro, and have spread to other regions of the country, such as São Paulo, Espírito Santo and Rio Grande do Sul, characterizing an epidemic. This outbreak is directly related to the …
Chromoblastomycosis is a chronic and progressive subcutaneous mycosis caused mainly by the fungus Fonsecae pedrosoi. The fungus can be found in its natural habitat (soil and plants) in conidia and mycelia forms. During the infections, exudatives lesions and granuloma (composed by macrophages, neutrophils, eosinophils and lymphocytes) are often observed in skin biopsies. Currently, little …
Chromoblastomycosis (CBM) is a chronic fungal disease that occurs in a variety of forms. It attacks the epidermis, dermis, subcutaneous, and may also present secondary infection, leading to lymphedema and occasionally squamous cell carcinoma. The infection is acquired in most cases by traumatic implantation, through the entrance of conidia, fragments of hyphae of the pathogen through the …
Chromoblastomycosis is a chronic subcutaneous fungal infection acquired by traumatic means, through the penetration of conidia and fragments of hyphae of the fungus by the solution of the skin continuity. Most of the reported cases of chromoblastomycosis have as etiological agent F. pedrosoi and mainly affect the countries of tropical and subtropical regions. In Brazil, the disease has be…
(Only some records are available in English at this moment)
Neutrophil extracellular trap (NET) formation (NETosis) is the newest effector function ascribed to neutrophils, during the last decade. Neutrophils generate NETs with their own DNA fibers that are coated with intracellular cytotoxic compounds. NETs have the capacity to trap and kill pathogens, extracellularly. NETosis is a programmed cell death that is different from apoptosis and necros…
Sporotrichosis is a subcutaneous mycosis caused by dimorphic fungi Sporothrix. Sporotrichosis is a reemerging disease at the moment it is a zoonosis, it affects cats and humans. Initially Sporothrix schenckii is single specie responsible for sporotrichosis. Subsequent genotypic and phenotypic studies the species was found high variability between isolates and established the existence of …
| 2 / 2 | Ongoing grants |
| 30 / 10 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 26 / 15 | Completed scholarships in Brazil |
| 3 / 2 | Completed scholarships abroad |
| 63 / 31 | All research grants and scholarships |
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