CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Degree in Medicine from Universidade Federal de São Paulo (1982), Master's in Molecular Biology from Universidade Federal de São Paulo (1985) and Ph.D. in Neuroscience from Universidade Federal de São Paulo (1988). Has experience in physiology, focusing on systems physiology, acting on the following topics: pilocarpine, epileptogenesis, epilepsy, R&D management. (Source: Lattes Curriculum)
Epilepsy is characterized by spontaneous recurrent seizures and is commonly associated with previous episode of traumatic brain injury or an episode of status epilepticus. Following the initial precipitating injury there is a silent period when plastic alterations occur on the nervous tissue culminating on recurrent seizures. Recently the neuroinflammation and glial role on epileptogeni...
Stress is a process associated to neuropsychophysiological reactions in the face of internal or external stimuli. Depending on its intensity, duration and frequency those stimuli might contribute for the development of several medical conditions such as hypertension, cardiovascular diseases and psychiatric problems to name a few. K12 teachers in Brazil have one of the most stressful jo...
It is known that often intense neuronal firing triggers the synthesis of proteins that require specific activation of expression of immediate early genes, the best known of these being c-Fos. This gene is related to neuronal activation and is expressed when the animal is exposed to new situations. Several studies with mice and rats showed expression of c-fos in various regions of the ce...
(Only some records are available in English at this moment)
Epilepsy is characterized by spontaneous recurrent seizures and is commonly associated with previous episode of traumatic brain injury or an episode of status epilepticus. Following the initial precipitating injury there is a silent period when plastic alterations occur on the nervous tissue culminating on recurrent seizures. Recently the neuroinflammation and glial role on epileptogeni...
The search for understanding the human nervous system and differences between us and other animals date back many centuries ago. Nowadays, it is already well established in the literature the most obvious anatomical differences between primates nonhuman and humans brain's, and those with other orders such as rodents. An important work of Novaes (2014) showed that there is not only anato...
Introduction: There is growing evidence that the exposure to untreated pain in the neonatal period could lead to changes to the brain plasticity, which in long-term would be related to an adverse neurodevelopmental outcome in premature newborns. Moreover, the treatment with opioid, considered the strongest analgesic drug used in the neonatal intensive care units is not free of deleterio...
(Only some records are available in English at this moment)
| 29 / 9 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 65 / 10 | Completed scholarships in Brazil |
| 95 / 20 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 8 |
| Citations | 39 |
| Cit./Article | 4.9 |
| Data from Web of Science | |
ENGELKE, DOUGLAS SENNA; FILEV, RENATO; MELLO, LUIZ E.; SANTOS-JUNIOR, JAIR GUILHERME. Evidence of memory generalization in contextual locomotor sensitization induced by amphetamine. Behavioural Brain Research, v. 317, p. 522-527, JAN 15 2017. Web of Science Citations: 1. (09/16307-2, 09/16305-0)
FILEV, RENATO; ENGELKE, DOUGLAS S.; DA SILVEIRA, DARTIU X.; MELLO, LUIZ E.; SANTOS-JUNIOR, JAIR G.. THC inhibits the expression of ethanol-induced locomotor sensitization in mice. ALCOHOL, v. 65, p. 31-35, DEC 2017. Web of Science Citations: 7. (09/16307-2)
MARCOS TEIXEIRA DE QUEIROZ‚ C.; EUGÊNIO MELLO‚ L.. Effects of herbimycin A in the pilocarpine model of temporal lobe epilepsy. Brain Research, v. 1081, n. 1, p. 219-227, 2006.
DOS SANTOS‚ J.G.; LONGO‚ B.M.; BLANCO‚ M.M.; MENEZES DE OLIVEIRA‚ M.G.; MELLO‚ L.E.. Behavioral changes resulting from the administration of cycloheximide in the pilocarpine model of epilepsy. Brain Research, v. 1066, n. 1, p. 37-48, 2005.
TORTORELLI, LUCAS SILVA; ENGELKE, DOUGLAS SENNA; LUNARDI, PAULA; MELLO E SOUZA, TADEU; SANTOS-JUNIOR, JAIR GUILHERME; GONCALVES, CARLOS-ALBERTO. Cocaine counteracts LPS-induced hypolocomotion and triggers locomotor sensitization expression. Behavioural Brain Research, v. 287, p. 226-229, JUL 1 2015. Web of Science Citations: 4. (09/16305-0)
COELHOSO, CASSIA C.; ENGELKE, DOUGLAS S.; FILEV, RENATO; SILVEIRA, DARTIU X.; MELLO, LUIZ E.; SANTOS-JUNIOR, JAIR G.. Temporal and Behavioral Variability in Cannabinoid Receptor Expression in Outbred Mice Submitted to Ethanol-Induced Locomotor Sensitization Paradigm. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, v. 37, n. 9, p. 1516-1526, SEP 2013. Web of Science Citations: 12. (09/16307-2, 09/16305-0, 11/03184-0)
A. TABOSA; Y. YAMAMURA; E.R. FORNO; L.E.A.M. MELLO. Effect of the acupoints ST-36 (Zusanli) and SP-6 (Sanyinjiao) on intestinal myoelectric activity of Wistar rats. Brazilian Journal of Medical and Biological Research, v. 35, n. 6, p. 731-739, Jun. 2002.
DOS SANTOS, JR., JAIR GUILHERME; FILEV, RENATO; COELHO, CAROLINA TESONE; YAMAMURA, YSAO; MELLO, LUIZ E.; TABOSA, ANGELA. Electroacupuncture Inhibits Ethanol-Induced Locomotor Sensitization and Alters homer1A mRNA Expression in Mice. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, v. 33, n. 8, p. 1469-1475, AUG 2009. Web of Science Citations: 7.
SUGAI, GISELE C. M.; FREIRE, ANAFLÁVIA DE O.; TABOSA, ANGELA; YAMAMURA, YSAO; TUFIK, SÉRGIO; MELLO, LUIZ EUGÊNIO A. M.. Serotonin involvement in the electroacupuncture- and moxibustion-induced gastric emptying in rats. Physiology & Behavior, v. 82, n. 5, p. 855-861, Oct. 2004.
FORESTI, MAIRA LICIA; ARISI, GABRIEL MAISONNAVE; CAMPBELL, JAMES J.; MELLO, LUIZ E.. Treatment with CCR2 antagonist is neuroprotective but does not alter epileptogenesis in the pilocarpine rat model of epilepsy. Epilepsy & Behavior, v. 102, JAN 2020. Web of Science Citations: 0. (16/08969-9, 15/11119-4)
DOS SANTOS‚ J.G.; LONGO‚ B.M.; BLANCO‚ M.M.; MENEZES DE OLIVEIRA‚ M.G.; MELLO‚ L.E.. Behavioral changes resulting from the administration of cycloheximide in the pilocarpine model of epilepsy. Brain Research, v. 1066, n. 1, p. 37-48, 2005.
TORTORELLI, LUCAS SILVA; ENGELKE, DOUGLAS SENNA; LUNARDI, PAULA; MELLO E SOUZA, TADEU; SANTOS-JUNIOR, JAIR GUILHERME; GONCALVES, CARLOS-ALBERTO. Cocaine counteracts LPS-induced hypolocomotion and triggers locomotor sensitization expression. Behavioural Brain Research, v. 287, p. 226-229, JUL 1 2015. Web of Science Citations: 4. (09/16305-0)
COELHOSO, CASSIA C.; ENGELKE, DOUGLAS S.; FILEV, RENATO; SILVEIRA, DARTIU X.; MELLO, LUIZ E.; SANTOS-JUNIOR, JAIR G.. Temporal and Behavioral Variability in Cannabinoid Receptor Expression in Outbred Mice Submitted to Ethanol-Induced Locomotor Sensitization Paradigm. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, v. 37, n. 9, p. 1516-1526, SEP 2013. Web of Science Citations: 12. (09/16307-2, 09/16305-0, 11/03184-0)
A. TABOSA; Y. YAMAMURA; E.R. FORNO; L.E.A.M. MELLO. Effect of the acupoints ST-36 (Zusanli) and SP-6 (Sanyinjiao) on intestinal myoelectric activity of Wistar rats. Brazilian Journal of Medical and Biological Research, v. 35, n. 6, p. 731-739, Jun. 2002.
DOS SANTOS, JR., JAIR GUILHERME; FILEV, RENATO; COELHO, CAROLINA TESONE; YAMAMURA, YSAO; MELLO, LUIZ E.; TABOSA, ANGELA. Electroacupuncture Inhibits Ethanol-Induced Locomotor Sensitization and Alters homer1A mRNA Expression in Mice. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, v. 33, n. 8, p. 1469-1475, AUG 2009. Web of Science Citations: 7.
SUGAI, GISELE C. M.; FREIRE, ANAFLÁVIA DE O.; TABOSA, ANGELA; YAMAMURA, YSAO; TUFIK, SÉRGIO; MELLO, LUIZ EUGÊNIO A. M.. Serotonin involvement in the electroacupuncture- and moxibustion-induced gastric emptying in rats. Physiology & Behavior, v. 82, n. 5, p. 855-861, Oct. 2004.
FORESTI, MAIRA LICIA; ARISI, GABRIEL MAISONNAVE; CAMPBELL, JAMES J.; MELLO, LUIZ E.. Treatment with CCR2 antagonist is neuroprotective but does not alter epileptogenesis in the pilocarpine rat model of epilepsy. Epilepsy & Behavior, v. 102, JAN 2020. Web of Science Citations: 0. (16/08969-9, 15/11119-4)
(References retrieved automatically from State of São Paulo Research Institutions)
BENASSI, Simone Kastropil. Plasticidade sináptica e epileptogênese em modelos de epilepsia do lobo temporal em ratos. 168 f. Tese (Doutorado) - Escola Paulista de Medicina. Universidade Federal de São Paulo (UNIFESP). São Paulo. (00/00254-2)
SAITO, Angélica Kiyomi. Efeitos da privação de sono paradoxal e da administração de drogas psicoativas na degeneração neuronal. 120 f. Tese (Doutorado) - Escola Paulista de Medicina. Universidade Federal de São Paulo (UNIFESP). São Paulo. (00/00665-2)
USO DE SAIS DE ESCOPOLAMINA PI9906220-8 - Luiz Eugênio Araújo de Moraes Mello. Luiz Eugênio Araújo de Moraes Mello; Christina Gonçalves Massant; Simone Kastropil Benassi - December 1999, 17
THE USE OF SCOPOLAMINE SALTS CA2395037 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Luiz Eugênio Araújo de Moraes Mello; Christina Gonçalves Massant; Simone Kastropil Benassi - December 2000, 14
USE OF ANTIMUSCARINIC DRUGS FOR PREVENTING THE ONSET OF EPILEPSY CA2516679 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Universidade Federal de São Paulo (UNIFESP). Luiz Eugenio Araujo de Moraes Mello; Simone Kastropil Benassi; Cristiane Gorgati; Cristina Gonçalves Massant - February 2004, 25
THE USE OF SCOPOLAMINE SALTS CN00819772 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Luiz Eugênio Araújo de Moraes Mello; Christina Gonçalves Massant; Simone Kastropil Benassi - December 2000, 14
USE OF ANTIMUSCARINIC DRUGS FOR PREVENTING THE ONSET OF EPILEPSY CN200480004992 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Universidade Federal de São Paulo (UNIFESP). Luiz Eugenio Araujo de Moraes Mello; Simone Kastropil Benassi; Cristiane Gorgati; Cristina Gonçalves Massant - February 2004, 25
THE USE OF SCOPOLAMINE SALTS DE2000629252 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Luiz Eugênio Araújo de Moraes Mello; Christina Gonçalves Massant; Simone Kastropil Benassi - December 2000, 14
USE OF ANTIMUSCARINIC DRUGS FOR PREVENTING THE ONSET OF EPILEPSY DE200460014344 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Universidade Federal de São Paulo (UNIFESP). Luiz Eugenio Araujo de Moraes Mello; Simone Kastropil Benassi; Cristiane Gorgati; Cristina Gonçalves Massant - February 2004, 25
THE USE OF SCOPOLAMINE SALTS EP20000982786 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Luiz Eugênio Araújo de Moraes Mello; Christina Gonçalves Massant; Simone Kastropil Benassi - December 2000, 14
USE OF ANTIMUSCARINIC DRUGS FOR PREVENTING THE ONSET OF EPILEPSY EP20040714246 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Universidade Federal de São Paulo (UNIFESP). Luiz Eugenio Araujo de Moraes Mello; Simone Kastropil Benassi; Cristiane Gorgati; Cristina Gonçalves Massant - February 2004, 25
THE USE OF SCOPOLAMINE SALTS KR1020030034038 - Luiz Eugênio Araújo de Moraes Mello. Luiz Eugênio Araújo de Moraes Mello; Christina Gonçalves Massant; Simone Kastropil Benassi - December 2000, 14
THE USE OF SCOPOLAMINE SALTS PA/a/2002/005727 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Luiz Eugênio Araújo de Moraes Mello; Christina Gonçalves Massant; Simone Kastropil Benassi - December 2000, 14
THE USE OF SCOPOLAMINE SALTS PCT/BR2000/000137 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Luiz Eugênio Araújo de Moraes Mello; Christina Gonçalves Massant; Simone Kastropil Benassi - December 2000, 14
USE OF ANTIMUSCARINIC DRUGS FOR PREVENTING THE ONSET OF EPILEPSY PCT/BR2004/000020 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Universidade Federal de São Paulo (UNIFESP). Luiz Eugenio Araujo de Moraes Mello; Simone Kastropil Benassi; Cristiane Gorgati; Cristina Gonçalves Massant - February 2004, 25
USO DE DROGAS ANTI-MUSCARÍNICAS PI0303123-3 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Universidade Federal de São Paulo (UNIFESP). Luiz Eugenio Araujo de Moraes Mello; Simone Kastropil Benassi; Cristiane Gorgati; Cristina Gonçalves Massant - February 2003, 24
THE USE OF SCOPOLAMINE SALTS US10/149,375 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Luiz Eugênio Araújo de Moraes Mello; Christina Gonçalves Massant; Simone Kastropil Benassi - December 2000, 14