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Pontifícia Universidade Católica de São Paulo (PUC-SP). Faculdade de Ciências Médicas e da Saúde (FCMS) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Eliana Aparecida de Rezende Duek in research grants and scholarships supported by FAPESP.
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Currently, 3D bio-printing stands as a pivotal technique in the realm of fabricating skeletal frameworks, furnishing a noteworthy advancement to the field of bone tissue engineering. Aiming to confer upon these printed scaffolds properties that faithfully mimic natural structures, considerable endeavors have been dedicated to the quest for materials that not only exhibit osteogenic charac…
In the last few decades, Bone Tissue Engineering (BTE) has been developed as an effective and alternative approach for treating large bone defects. Three-dimensional (3D) bioprinting is an emerging technology expected to revolutionize the field of tissue engineering and regenerative medicine. Several efforts have been made to stimulate bone regeneration by the release of osteogenic small …
Currently there are several dermal substitutes, but these are also associated with a range of problems such as reduced vascularization, formation of excessive fibrosis, lack of flexibility, inability to maintain hydration of the wound, among others. This study proposes to develop a skin equivalent that meets any of the above requirements. The device bilayer developed is composed of polyvi…
Hydrogels have been widely studied, especially as injectable materials for applications as biomaterials. These hydrogels may possess thermosensitive features near body temperature (LCST - Lower Critical Solution Temperature - around 37ºC), in addition to rapid gelation, which allows it use as carrier drugs, cells or cell growth factors as injections. The current challenge is to make these…
(Only some records are available in English at this moment)
Myocardial infarction (MI) is widely recognized as the leading cause of mortality associated with cardiovascular diseases globally. Projections indicate that by 2030, more than 23.6 million deaths will be attributed to this condition. MI results in significant cardiomyocyte death, triggering the formation of fibrous tissue in the myocardial wall. This process leads to an interruption of i…
The use of bandages made of hydrogel modified with anti-inflammatory and regenerative drugs to assist cutaneous regeneration, as well as benefit inflammatory processes, has a high relevance in medical and tissue engineering fields. In this context, Pluronic®, an biologically inert, synthetic and thermo-responsive hydrogel that may be applied as bioink or bandages, is capable of being modi…
The bioluminescent reporter genes that encode luciferases are among the most sensitive and frequently used to monitor non-invasively cellular processes, in real time. Unlike fluorescent reporter genes such as GFP, which have disadvantages such as autoabsorption of irradiated light, autofluorescence and phototoxicity, bioluminescent reporter genes have the advantage of producing their own …
Hydrogels have been widely studied, especially as injectable materials for applications as biomaterials. These hydrogels may possess thermosensitive features near body temperature (LCST - Lower Critical Solution Temperature - around 37oC), in addition to rapid gelation, which allows it use as carrier drugs, cells or cell growth factors as injections. The current challenge is to make these…
In the treatment of a skin wound is necessary to know all the physiological process of wound healing, because there are situations when is necessary to take actions to optimize it. In complex wounds is necessary skin autograft, but, sometimes, there is not the appropriate amount of donor area, or the receptor area is not in conditions to receive the graft. Thus, one alternative is the use…
The biofunctionalization of bioresorbable polymeric scaffolds by chemical immobilization of natural molecules with bioactive and osteoinductive properties, capable of being naturally recognized by the native bone tissue, stimulating osteogenesis process and tissue repair, from the cultivation of human mesenchymal stem cells (hCTMs ) on these materials, is a promising strategy in Bone Tis…
(Only some records are available in English at this moment)
Myocardial infarction (MI) is the leading cause of global mortality associated with cardiovascular diseases. MI leads to the death of cardiomyocytes and the formation of fibrous tissue, impairing the electrical signaling of the myocardium and resulting in cardiac dysfunction. Current therapies do not effectively promote the regeneration of the affected area. Injectable bioactive hydrogels…
The firefly luciferin-luciferase system has been used in an enormous variety of bioanalytical applications. Firefly luciferase genes have been widely used as reporters in gene expression studies and for cell tracking in biological and pathological processes, including cell proliferation studies, cytotoxicity assays, and metastasis in model animals, emerging as a novel technology replacing…
The use of bandages made of hydrogel modified with anti-inflammatory and regenerative drugs to step up cutaneous regeneration and control the inflammatory processes has high relevance in medical and tissue engineering fields. In this context, Pluronic, a biologically inert, synthetic, and thermo-responsive hydrogel that may be applied as bioink or bandages, is chemically modifiable, and t…
The class of hydrogels has been developed since past years, mainly the injectable materials. These types of materials showed thermoresponsive temperatures near human body conditions (37ºC) named LCST - Low Critical Solution Temperature. The primary challenge of this hydrogels is tunable mechanical properties and biodegradability of these materials in vitro for posterior use in vivo. The p…
| 1 / 1 | Ongoing grants |
| 15 / 9 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 29 / 9 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 3 / 3 | Completed scholarships abroad |
| 52 / 26 | All research grants and scholarships |
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