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Geraldo Aleixo da Silva Passos Júnior

CV Lattes GoogleMyCitations


Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

bachelor's at Ciências Biológicas from Universidade Estadual Paulista Júlio de Mesquita Filho (1983), master's at Biochemistry from Universidade de São Paulo (1986) and doctorate at Biochemistry from Universidade de São Paulo (1988). Has experience in Immunology, focusing on Imunogenetics, acting on the following subjects: microarrays, transcriptoma, cluster and tree view, timo and rna. (Source: Lattes Curriculum)

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Study advances understanding of how autoimmune diseases develop  
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Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (37)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications20
Citations252
Cit./Article12.6
Data from Web of Science

CARMINATI, PATRICIA OLIVEIRA; MELLO, STEPHANO SPANO; FACHIN, ANA LUCIA; JUNTA, CRISTINA MORAES; SANDRIN-GARCIA, PAULA; CARLOTTI, CARLOS GILBERTO; DONADI, EDUARDO ANTONIO; SILVA PASSOS, GERALDO ALEIXO; SAKAMOTO-HOJO, ELZA TIEMI. Alterations in gene expression profiles correlated with cisplatin cytotoxicity in the glioma U343 cell line. GENETICS AND MOLECULAR BIOLOGY, v. 33, n. 1, p. 159-168, . Web of Science Citations: 6. (99/12135-9)

FACHIN, ANA LUCIA; MELLO, STEPHANO SPANO; SANDRIN-GARCIA, PAULA; JUNTA, CRISTINA MORAES; GHILARDI-NETTO, THOMAZ; DONADI, EDUARDO ANTONIO; DA SILVA PASSOS, GERALDO ALEIXO; SAKAMOTO-HOJO, ELZA TIEMI. Gene Expression Profiles in Radiation Workers Occupationally Exposed to Ionizing Radiation. JOURNAL OF RADIATION RESEARCH, v. 50, n. 1, p. 61-71, . Web of Science Citations: 44. (99/12135-9)

DONATE, PAULA B.; FORNARI, THAIS A.; MACEDO, CLAUDIA; CUNHA, THIAGO M.; NASCIMENTO, DANIELE C. B.; SAKAMOTO-HOJO, ELZA T.; DONADI, EDUARDO A.; CUNHA, FERNANDO Q.; PASSOS, GERALDO A.. T Cell Post-Transcriptional miRNA-mRNA Interaction Networks Identify Targets Associated with Susceptibility/Resistance to Collagen-induced Arthritis. PLoS One, v. 8, n. 1, . Web of Science Citations: 14. (08/56594-8)

MANOEL-CAETANO, FERNANDA S.; XAVIER, DANILO J.; EVANGELISTA, ADRIANE F.; TAKAHASHI, PAULA; COLLARES, CRISTHIANNA V.; PUTHIER, DENIS; FOSS-FREITAS, MARIA C.; FOSS, MILTON C.; DONADI, EDUARDO A.; PASSOS, GERALDO A.; et al. Gene expression profiles displayed by peripheral blood mononuclear cells from patients with type 2 diabetes mellitus focusing on biological processes implicated on the pathogenesis of the disease. Gene, v. 511, n. 2, p. 151-160, . Web of Science Citations: 26. (10/12069-7, 08/56594-8)

SANDRIN-GARCIA‚ P.; MACEDO‚ C.; MARTELLI‚ LR; RAMOS‚ ES; GUION-ALMEIDA‚ ML; RICHIERI-COSTA‚ A.; PASSOS‚ GAS. Recurrent 22q11. 2 deletion in a sibship suggestive of parental germline mosaicism in velocardiofacial syndrome. Clinical Genetics, v. 61, n. 5, p. 380-383, .

MACEDO‚ C.; MORAES JUNTA‚ C.; PASSOS‚ G.A.S.. Onset of T-cell receptor V [beta] 8.1 and D [beta] 2.1 V (D) J recombination during thymus development of inbred mouse strains. Immunology Letters, v. 69, n. 3, p. 371-373, .

DA SILVA‚ M.I.; PASSOS‚ G.A.S.. The human immunoglobulin variable lambda locus IGLV9 gene is a monomorphic marker in the urban Brazilian population. Immunology Letters, v. 69, n. 3, p. 369-370, .

MORAES JUNTA‚ C.; PASSOS‚ G.A.S.. Genomic EcoRI polymorphism and cosmid sequencing reveal an insertion/deletion and a new IGLV5 allele in the human immunoglobulin lambda variable locus (22q11. 2/IGLV). IMMUNOGENETICS, v. 55, n. 1, p. 10-15, .

TREVISAN‚ G.L.; RASSI‚ D.M.; BAIÃO‚ A.M.T.; SANDRIN-GARCIA‚ P.; MELLO‚ S.S.; TAMIA-FERREIRA‚ M.C.; JUNTA‚ C.M.; FACHIN‚ A.L.; MARQUES‚ M.; SAKAMOTO-HOJO‚ E.T.; et al. Using cDNA microarrays to identify human CD19+ B cell gene products (ESTs) originated from systemic lupus erythematosus susceptibility loci. AUTOIMMUNITY REVIEWS, v. 5, n. 5, p. 319-323, . (99/12135-9)

RASSI‚ D.M.; JUNTA‚ C.M.; FACHIN‚ A.N.A.L.; SANDRIN-GARCIA‚ P.; MELLO‚ S.S.; FERNANDES‚ A.N.A.P.M.; DEGHAIDE‚ N.N.H.S.; FOSS-FREITAS‚ M.C.; FOSS‚ M.C.; SAKAMOTO-HOJO‚ E.T.; et al. Is HLA Class II Profile Relevant for the Study of Large-Scale Differentially Expressed Genes in Type 1 Diabetes Mellitus Patients?. Annals of the New York Academy of Sciences, v. 1079, n. 1, p. 305-309, . (99/12135-9)

RASSI‚ D.M.; JUNTA‚ C.M.; FACHIN‚ A.N.A.L.; SANDRIN-GARCIA‚ P.; MELLO‚ S.; MARQUES‚ M.; FERNANDES‚ A.N.A.P.M.; FOSS-FREITAS‚ M.C.; FOSS‚ M.C.; SAKAMOTO-HOJO‚ E.T.; et al. Metabolism genes are among the differentially expressed ones observed in lymphomononuclear cells of recently diagnosed type 1 diabetes mellitus patients. Annals of the New York Academy of Sciences, v. 1079, n. 1, p. 171-176, . (99/12135-9)

PEREIRA‚ E.; TAMIA-FERREIRA‚ M.C.; CARDOSO‚ R.S.; MELLO‚ S.S.; SAKAMOTO-HOJO‚ E.T.; PASSOS‚ G.A.S.; DONADI‚ E.A.. Immunosuppressive therapy modulates T lymphocyte gene expression in patients with systemic lupus erythematosus. Immunology, v. 113, n. 1, p. 99-105, . (99/12135-9)

SILVA‚ G.L.; JUNTA‚ C.M.; MELLO‚ S.S.; GARCIA‚ P.S.; RASSI‚ D.M.; SAKAMOTO-HOJO‚ E.T.; DONADI‚ E.A.; PASSOS‚ G.A.S.. Profiling Meta-Analysis Reveals Primarily Gene Coexpression Concordance between Systemic Lupus Erythematosus and Rheumatoid Arthritis. Annals of the New York Academy of Sciences, v. 1110, n. 1, p. 33-46, . (99/12135-9)

CARDOSO‚ R.S.; JUNTA‚ C.M.; MACEDO‚ C.; MAGALHÃES‚ D.A.R.; SILVEIRA‚ E.L.V.; PAULA‚ M.O.; MARQUES‚ M.; MELLO‚ S.S.; ZÁRATE-BLADÉS‚ C.R.; NGUYEN‚ C.; et al. Hybridization signatures of gamma-irradiated murine fetal thymus organ culture (FTOC) reveal modulation of genes associated with T-cell receptor V (D) J recombination and DNA repair. Molecular Immunology, v. 43, n. 5, p. 464-472, . (99/12135-9)

SOUSA CARDOSO‚ R.; MAGALHÃES‚ D.A.R.; BAIÃO‚ A.M.T.; JUNTA‚ C.M.; MACEDO‚ C.; MARQUES‚ M.; SAKAMOTO-HOJO‚ E.T.; DONADI‚ E.A.; PASSOS‚ G.A.S.. Onset of promiscuous gene expression in murine fetal thymus organ culture. Immunology, v. 119, n. 3, p. 369-375, . (99/12135-9)

FACHIN‚ A.L.; MELLO‚ S.S.; SANDRIN-GARCIA‚ P.; JUNTA‚ C.M.; DONADI‚ E.A.; PASSOS‚ G.A.S.; SAKAMOTO-HOJO‚ E.T.. Gene expression profiles in human lymphocytes irradiated in vitro with low doses of gamma rays. RADIATION RESEARCH, v. 168, n. 6, p. 650-665, . (99/12135-9)

BASSI, C. L.; MELLO, S. S.; CARDOSO, R. S.; GODOY, P. D. V.; FACHIN, A. L.; JUNTA, C. M.; SANDRIN-GARCIA, P.; CARLOTTI, C. G.; FALCAO, R. P.; DONADI, E. A.; et al. Transcriptional changes in U343 MG-a glioblastoma cell line exposed to ionizing radiation. HUMAN & EXPERIMENTAL TOXICOLOGY, v. 27, n. 12, p. 919-929, . Web of Science Citations: 14. (99/12135-9)

PEZZI, NICOLE; ASSIS, AMANDA FREIRE; COTRIM-SOUSA, LARISSA COTRIM; LOPES, GABRIEL SARTI; MOSELLA, MARITZA SALAS; LIMA, DJALMA SOUSA; BOMBONATO-PRADO, KARINA F.; PASSOS, GERALDO ALEIXO. Aire knockdown in medullary thymic epithelial cells affects Aire protein, deregulates cell adhesion genes and decreases thymocyte interaction. Molecular Immunology, v. 77, p. 157-173, . Web of Science Citations: 5. (13/17481-1)

PASSOS, GERALDO A.; SPECK-HERNANDEZ, CESAR A.; ASSIS, AMANDA F.; MENDES-DA-CRUZ, DANIELLA A.. Update on Aire and thymic negative selection. IMMUNOLOGY, v. 153, n. 1, p. 10-20, . Web of Science Citations: 8. (13/17481-1)

XAVIER, DANILO J.; TAKAHASHI, PAULA; EVANGELISTA, ADRIANE F.; FOSS-FREITAS, MARIA C.; FOSS, MILTON C.; DONADI, EDUARDO A.; PASSOS, GERALDO A.; SAKAMOTO-HOJO, ELZA T.. Assessment of DNA damage and mRNA/miRNA transcriptional expression profiles in hyperglycemic versus non-hyperglycemic patients with type 2 diabetes mellitus. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, v. 776, n. SI, p. 98-110, . Web of Science Citations: 12. (10/12069-7, 08/56594-8)

MACEDO, CLAUDIA; OLIVEIRA, ERNNA H.; ALMEIDA, RENATA S.; DONATE, PAULA B.; FORNARI, THAIS A.; PEZZI, NICOLE; SAKAMOTO-HOJO, ELZA T.; DONADI, EDUARDO A.; PASSOS, GERALDO A.. Aire-dependent peripheral tissue antigen mRNAs in mTEC cells feature networking refractoriness to microRNA interaction. Immunobiology, v. 220, n. 1, p. 93-102, . Web of Science Citations: 10. (13/17481-1, 13/08216-2, 08/56594-8)

XAVIER, DANILO J.; TAKAHASHI, PAULA; MANOEL-CAETANO, FERNANDA S.; FOSS-FREITAS, MARIA C.; FOSS, MILTON C.; DONADI, EDUARDO A.; PASSOS, GERALDO A.; SAKAMOTO-HOJO, ELZA T.. One-week intervention period led to improvements in glycemic control and reduction in DNA damage levels in patients with type 2 diabetes mellitus. Diabetes Research and Clinical Practice, v. 105, n. 3, p. 356-363, . Web of Science Citations: 6. (10/12069-7, 08/56594-8)

TAKAHASHI, PAULA; XAVIER, DANILO J.; EVANGELISTA, ADRIANE F.; MANOEL-CAETANO, FERNANDA S.; MACEDO, CLAUDIA; COLLARES, CRISTHIANNA V. A.; FOSS-FREITAS, MARIA C.; FOSS, MILTON C.; RASSI, DIANE M.; DONADI, EDUARDO A.; et al. MicroRNA expression profiling and functional annotation analysis of their targets in patients with type 1 diabetes mellitus. Gene, v. 539, n. 2, p. 213-223, . Web of Science Citations: 33. (10/12069-7, 08/56594-8)

FORNARI, THAIS A.; DONATE, PAULA B.; ASSIS, AMANDA F.; MACEDO, CLAUDIA; SAKAMOTO-HOJO, ELZA T.; DONADI, EDUARDO A.; PASSOS, GERALDO A.. Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice. PLoS One, v. 10, n. 11, . Web of Science Citations: 12. (13/08216-2, 08/56594-8)

PASSOS, GERALDO ALEIXO; MENDES-DA-CRUZ, DANIELLE AREAS; OLIVEIRA, ERNNA HERIDA. The thymic orchestration involving Aire, miRNAs, and cell-cell interactions during the induction of central tolerance. FRONTIERS IN IMMUNOLOGY, v. 6, . Web of Science Citations: 13. (13/17481-1, 13/08216-2)

COLLARES, C. V. A.; EVANGELISTA, A. F.; XAVIER, D. J.; TAKAHASHI, P.; ALMEIDA, R.; MACEDO, C.; MANOEL-CAETANO, F.; FOSS, M. C.; FOSS-FREITAS, M. C.; RASSI, D. M.; et al. Transcriptome meta-analysis of peripheral lymphomononuclear cells indicates that gestational diabetes is closer to type 1 diabetes than to type 2 diabetes mellitus. MOLECULAR BIOLOGY REPORTS, v. 40, n. 9, p. 5351-5358, . Web of Science Citations: 11. (10/12069-7, 08/56594-8)

DERNOWSEK, JANAINA A.; PEREIRA, MILENA C.; FORNARI, THAIS A.; MACEDO, CLAUDIA; ASSIS, AMANDA F.; DONATE, PAULA B.; BOMBONATO-PRADO, KARINA F.; PASSOS-BUENO, MARIA RITA; PASSOS, GERALDO A.. Posttranscriptional Interaction Between miR-450a-5p and miR-28-5p and STAT1 mRNA Triggers Osteoblastic Differentiation of Human Mesenchymal Stem Cells. Journal of Cellular Biochemistry, v. 118, n. 11, p. 4045-4062, . Web of Science Citations: 8.

SPECK-HERNANDEZ, CESAR A.; ASSIS, AMANDA F.; FELICIO, RAFAELA F.; COTRIM-SOUSA, LARISSA; PEZZI, NICOLE; LOPES, GABRIEL S.; BOMBONATO-PRADO, KARINA F.; GIULIATTI, SILVANA; PASSOS, GERALDO A.. Aire Disruption Influences the Medullary Thymic Epithelial Cell Transcriptome and Interaction With Thymocytes. FRONTIERS IN IMMUNOLOGY, v. 9, . Web of Science Citations: 0. (13/17481-1)

EVANGELISTA, ADRIANE F.; COLLARES, CRISTHIANNA V. A.; XAVIER, DANILO J.; MACEDO, CLAUDIA; MANOEL-CAETANO, FERNANDA S.; RASSI, DIANE M.; FOSS-FREITAS, MARIA C.; FOSS, MILTON C.; SAKAMOTO-HOJO, ELZA T.; NGUYEN, CATHERINE; et al. Integrative analysis of the transcriptome profiles observed in type 1, type 2 and gestational diabetes mellitus reveals the role of inflammation. BMC MEDICAL GENOMICS, v. 7, . Web of Science Citations: 17. (10/12069-7, 08/56594-8)

OLIVEIRA, ERNNA H.; MACEDO, CLAUDIA; COLLARES, CRISTHIANNA V.; FREITAS, ANA CAROLINA; DONATE, PAULA BARBIM; SAKAMOTO-HOJO, ELZA T.; DONADI, EDUARDO A.; PASSOS, GERALDO A.. Aire Downregulation Is Associated with Changes in the Posttranscriptional Control of Peripheral Tissue Antigens in Medullary Thymic Epithelial Cells. FRONTIERS IN IMMUNOLOGY, v. 7, . Web of Science Citations: 4. (13/17481-1, 08/56594-8)

MENDES-DA-CRUZ, DANIELLA A.; LEMOS, JULIA P.; PASSOS, GERALDO A.; SAVINO, WILSON. Abnormal T-Cell Development in the Thymus of Non-obese Diabetic Mice: Possible Relationship With the Pathogenesis of Type 1 Autoimmune Diabetes. FRONTIERS IN ENDOCRINOLOGY, v. 9, . Web of Science Citations: 1. (13/17481-1)

MELLO, STEPHANO S.; FACHIN, ANA L.; JUNTA, CRISTINA M.; SANDRIN-GARCIA, PAULA; DONADI, EDUARDO A.; PASSOS, GERALDO A. S.; SAKAMOTO-HOJO, ELZA T.. Delayed Effects of Exposure to a Moderate Radiation Dose on Transcription Profiles in Human Primary Fibroblasts. Environmental and Molecular Mutagenesis, v. 52, n. 2, p. 117-129, . Web of Science Citations: 8. (99/12135-9)

PASSOS‚ G.A.S.; PROENÇA PICANÇO‚ V.. Frequency of the δ< i> ccr 5 deletion allele in the urban Brazilian population. Immunology Letters, v. 61, n. 2, p. 205-207, .

SAKAMOTO-HOJO, E. T.; PEREIRA, E.; FACHIN, A. L.; CARDOSO, R. S.; DONADI, E. A.; PASSOS, G. A. S.; MELLO, S. S.; JUNTA, C. M.. Gene expression profiles in human cells submitted to genotoxic stress. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH, v. 544, n. 2-3, p. 403-413, . (99/12135-9)

TREVISAN, G. L.; TAMIA-FERREIRA, M. C.; PASSOS, G. A. S.; JUNTA, C. M.. Immunoglobulin V-lambda transcription profiling of systemic lupus erythematosus patients reveals biased usage of genes located near the J lambda-C lambda segments. Scandinavian Journal of Immunology, v. 59, n. 4, p. 395-399, . (99/12135-9)

MAGALHÃES, DANIELLE A. R.; MACEDO, CLAUDIA; JUNTA, CRISTINA M.; MELLO, STEPHANO S.; MARQUES, MÁRCIA M. C.; CARDOSO, RENATO S.; SAKAMOTO-HOJO, ELZA T.; DONADI, EDUARDO A.; PASSOS, GERALDO A. S.. Hybridization signatures during thymus ontogeny reveals modulation of genes coding for T-cell signaling proteins. Molecular Immunology, v. 42, n. 9, p. 1043-1048, . (99/12135-9)

R.G.P. QUEIROZ; M.C. TAMIA-FERREIRA; I.F. CARVALHO; F.C. PETEAN; G.A.S. PASSOS. Association between EcoRI fragment-length polymorphism of the immunoglobulin lambda variable 8 (IGLV8) gene family with rheumatoid arthritis and systemic lupus erythematosus. Brazilian Journal of Medical and Biological Research, v. 34, n. 4, p. 525-528, .

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

ESPANHOL, Aline Renata. Cinética da expressão gênica diferencial durante a ontogenia do timo. 2002. 73f. Dissertação (Mestrado) - Centro de Ciências Biológicas e da Saúde. Universidade Federal de São Carlos (UFSCAR). São Carlos. (00/01705-8)

MAGALHÃES, Danielle Aparecida Rosa de. Análise do transcriptoma durante a ontogenia do timo.. 2007. Tese (Doutorado) – Faculdade de Medicina de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto. (03/00982-6)

TAVARES, Thais Arouca Fornari. Análise da expressão gênica promíscua no timo de camundongos NOD (non obese diabetic) durante a emergência do Diabetes melitus tipo 1. 2008. Dissertação (Mestrado) - Faculdade de Medicina de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto. (05/57231-8)

CARDOSO, Renato Sousa. Avaliação dos efeitos da radiação gama na expressão de genes reguladores da recombinação V(D)J de receptores de células T. 2004. 172f. Tese (Doutorado) – Faculdade de Medicina de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto. (00/09994-9)

OLIVEIRA, Ernna Hérida Domingues de. Vias de regulação da expressão gênica promíscua no timo envolve Aire e microRNAs. 2013. Tese (Doutorado) – Faculdade de Medicina de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto. (09/54694-8)

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