CV Lattes
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Universidade Cruzeiro do Sul (UNICSUL). Centro de Ciências Biológicas e da Saúde (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduate in Biology at Universidade Federal do Paraná (1996-2000), PhD in Science (Human Physiology) at University of São Paulo (2001-2005), Post-doc at the University of Sao Paulo (2005-2007) and University of Geneva (2007), Visiting Scholar Scientist at Yale University (2018-2019), and Visiting Researcher at Butantan Institute (2020-actual). He has experience in Physiology, with emphasis on Endocrine Physiology, Metabolism, and Exercise Physiology. He has expertise in the following subareas: fatty acids, insulin resistance, skeletal muscle metabolism, cell signaling, mitochondrial function and physical exercise. He also works with the COVID-19 pancemic, in the following area: epidemilogy, awareness and scientific information, impact, and treatments. He is a scientific adviser of FAPESP, CNPq, and CAPES; editor and reviewer of important international journals. Nowadays, he acts as Titular Professor of the Interdisciplinary Post-Graduate Program in Health Sciences, Institute of Physical Activity Sciences and Sports (ICAFE), Cruzeiro do Sul University. (Source: Lattes Curriculum)
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Peripheral Insulin Resistance (IR) and inflammation follow the development of Type 2 Diabetes Mellitus (DM2), with a high prevalence in obese patients. However, a significant percentage of non-obese individuals present DM2, especially in specific regions. For example, in Brazil, this percentage reaches 10 to 20%, while, in Japan, about 60% of type 2 diabetic patients have no Obesity. The …
The Prof. Dr. Philip Newsholme's visit will be important to discuss, direct, and strengthen actions for promoting collaborative academic-scientific activities among the research institutions of this proposal, as well as for contributing to the learning and establishment of new methodologies between Curtin University (Perth, Australia) and Brazilin research institutions from the Sao Paulo …
MicroRNAs (miRNAs) are involved in the control of energy metabolism and development of chronic diseases, such as obesity, T2DM, and metabolic syndrome. The identification of miRNAs associated with T2DM development is essential to understand the syndrome etiology and direct futher therapeutic studies. This project aims to characterize the expression profile of circulating exosomal miRNAs i…
Inflammation and insulin resistance are common in several chronic diseases, such as obesity, type 2 diabetes mellitus, metabolic syndrome, cancer, and cardiovascular diseases. Various studies show a relationship between these two factors, although the mechanisms involved are not completely understood yet. Here, we discuss the molecular basis of insulin resistance and inflammation and the …
(Only some records are available in English at this moment)
Peripheral insulin resistance and inflammation accompany the development of type 2 diabetes mellitus (DM2), with a high prevalence in obese patients. However, a high percentage of lean individuals have DM2, especially in certain regions. For example, in Brazil, the percentage reaches 10% to 20%, while in Japan, around 60% of patients with DM2 are non-obese. The causes associated with the …
Overweight and obesity are related to several disorders, such as insulin resistance, chronic inflammation, Type 2 Diabetes Mellitus, cardiovascular diseases, dyslipidemia, metabolic syndrome, and cancer. Brown Adipose Tissue (BAT) has been proposed as a potential intervention for obesity because its high metabolic capacity to dissipate energy as heat without ATP synthesis, enhancing energ…
(Only some records are available in English at this moment)
Energy balance is defined by two components: energy intake and energy expenditure. Even minor but chronic perturbations in either of these two components can lead to an increase (obesity) or decrease in body weight. Obesity is not only a significant problem in itself but is also a major inducer of type 2 diabetes, cardiovascular disease and certain forms of cancer. At present there is no …
Epigenetic modifications are one of the most important means for control of gene activity; in essence to store, retain, and recall past experiences in a way to shape present and future behaviour. Over the last decade we have characterised the key epigenetic changes imprinted following exposure to high glucose levels. In addition, we have shown that this epigenetic programming directly con…
Insulin resistance (IR) is observed in several conditions, including obesity, type 2 diabetes mellitus and metabolic syndrome. Under these conditions an increase in pro-inflammatory factors and oxidative stress has been observed, which may play an important role in activation of pathways related to skeletal muscle (ME) wasting (atrophy) and a shift toward fast twitch, glycolytic fibers, w…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 9 / 7 | Completed research grants |
| 12 / 10 | Completed scholarships in Brazil |
| 5 / 5 | Completed scholarships abroad |
| 27 / 23 | All research grants and scholarships |
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