CV Lattes
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Sociedade Beneficente de Senhoras (SBSHSL). Hospital Sírio-Libanês (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Faculdade de Ciências Exatas e Experimentais from Universidade Presbiteriana Mackenzie (1998), master's at Patologia Experimental e Comparada from Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (2001) and ph.d. at Patologia Experimental e Comparada from Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (2005). 2006-2009 Post Doc at Departamento de Fisiologia e Biofísica do Instituto de Ciências Biomédicas da USP. Today is Scientific Researcher of Group of Neuromodulation and Experimental Pain at Instituto de Ensino e Pesquisa do Hosptital Sírio-Libanês. Has experience in Patophysiology of Pain and of Inflammation , acting on the following subjects: antinociception, neuropathic pain, inflammation response, neurophysiology, pain suppressor system, cortical electrical stimulation and nociceptive plasticity. (Source: Lattes Curriculum)
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Chemotherapy-induced neuropathic pain (CINP) has a very high prevalence (between 50 and 80% of cases) negatively impacting the quality of life of patients and may lead to treatment discontinuation. Preventive or symptomatic treatments for CINP are generally ineffective, making it necessary to investigate new therapeutic approaches that prevent or improve these symptoms. In this sense, per…
Parkinson's Disease (PD) is a complex neurodegenerative disease that causes progressive dysfunction of dopaminergic and non-dopaminergic neurons, associated with chronic inflammatory response in the central nervous system. PD includes motor and non-motor symptoms, and its treatment is eminently symptomatic, starting with an effective pharmacological approach that loses its effect over tim…
Neuropathic pain (NP), resulting from injury or dysfunction of the nervous system somatosensory, generates a complex disease which treatment is difficult, resulting in a serious public health problem. New therapeutic approaches are needed as an alternative for patients refractory to pharmacological and surgical interventions. Accordingly, the transcranial direct-current stimulation (tDCS)…
Parkinson's disease (PD) is a neurodegenerative disorder characterized by progressive loss of nigrostriatal dopamine neurons, resulting in extrapiramidal motor control alterations. Most part of DP patients relates pain, sometimes previously to motor and cognitives disorders, typical symptoms of disease. Experimentally, the reduction of nociceptive threshold in parkinsonian rats in differe…
(Only some records are available in English at this moment)
Chemotherapy-induced neuropathic pain (CINP) has a very high prevalence (between 50% and 80% of cases), negatively impacting patients' quality of life and potentially leading to treatment discontinuation. Preventive or symptomatic treatments for CINP are generally ineffective, making it necessary to investigate new therapeutic approaches that can prevent or improve these symptoms. In this…
Type 2 diabetes mellitus (DM2) is one of the most prevalent non-communicating diseases today, characterized by acquired insulin resistance. On the other hand, Parkinson's disease (PD) is the third most prevalent neurodegenerative disease in the world, being characterized by the progressive death of dopaminergic neurons in the nigrostriatal pathway, compromising the motor circuitry. Despit…
Chemotherapy-induced neuropathic pain (CINP) pain, such as oxaliplatin, has a very high prevalence (between 50 and 80% of cases) negatively impacting the quality of life of patients and may lead to treatment discontinuation. CINP preventive or symptomatic treatments are generally ineffective, making it necessary to investigate new therapeutic approaches to prevent or improve these symptom…
Neuropathic pain (ND) is a complex disorder, induced by injury or disease of the somatosensory system, which significantly compromises the quality of life of the individual. Conventional pharmacological treatments induce pain relief in about one third of patients, making it necessary to search or improve more effective treatments. Low frequency dense and dispersed electroacupuncture (EA) …
Diffuse intrinsic pontine glioma (DIPG) is a highly aggressive, lethal pediatric tumor with few treatment options, most of which are ineffective regarding patient survival. Considering that DIPG cannot be removed surgically due to the anatomical complexity and eloquence of the tumor area and that this brain area has a restrictive nature of the blood-brain barrier, thus preventing the arri…
(Only some records are available in English at this moment)
Despite its widespread use, the underlying mechanisms of high frequency stimulation (HFS), as used in deep brain stimulation (DBS) therapy, remain unknown. HFS has been shown to directly modulate astrocyte activation, contributing to HFS beneficial effects. In this context, astrocytes may be considered key players in promoting the wide range of observed HFS therapeutic effects. Reactive a…
| 1 / 1 | Ongoing grants |
| 4 / 4 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 21 / 11 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 29 / 19 | All research grants and scholarships |
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